Restrictions

Referee reports in boxes 37, 38, and 39 are restricted until the death of Leslie Orgel.

Abstract

Papers of Leslie Orgel, chemist, molecular biologist and Senior Fellow and Research Professor at the Salk Institute for Biological Studies, where he directs the Chemical Evolution Laboratory. Orgel's research interests include nucleic acid chemistry, molecular evolution, prebiotic chemistry, and problems related to the origin of life. The bulk of the papers dates from 1964 to 1991 and includes correspondence, journal articles, conference and meeting material, contracts and grants, subject files, Salk Institute administrative files, and referee reports. The papers are arranged in eight series: 1) BIOGRAPHICAL MATERIAL, 2) CORRESPONDENCE, 3) WRITINGS, 4) CONTRACTS, GRANTS AND PROPOSALS, 5) CONFERENCES AND MEETINGS, 6) SUBJECT FILES, 7) SALK INSTITUTE, and 8) REFEREE REPORTS.

Biography

Leslie Eleazer Orgel was born in London, England, on January 12, 1927. He received his B.A. in chemistry with first class honors from Oxford university in 1949. In 1950 he was elected a Fellow of Magdalen College and in 1951 was awarded his Ph.D in chemistry at Oxford.

Orgel started his career as a theoretical inorganic chemist and continued his studies in this field at Oxford, the California Institute of Technology and the University of Chicago. In 1955 he joined the chemistry department at Cambridge university.

There he did work in transition metal chemistry, published articles and wrote a textbook entitled TRANSITION METAL CHEMISTRY: LIGAND FIELD THEORY (1960).

In 1964 Orgel was appointed Senior Fellow and Research Professor at the Salk Institute for Biological Studies, where he directs the Chemical Evolution Laboratory. He is also an adjunct professor in the Department of Chemistry and Biochemistry at the University of California, San Diego, and he is one of five principal investigators in the NASA-sponsored NSCORT program in exobiology. Orgel also participated in NASA's Viking Mars Lander Program as a member of the Molecular Analysis Team that designed the gas chromatography mass spectrometer instrument.

Orgel's work in the Chemical Evolution Laboratory is in nucleotide chemistry and is mainly concerned with non-enzymatic polymerization reactions that depend on the formation of double-helical complexes between a preformed polynucleotide template and one or more complementary mononucleotide or polynucleotide substrates. In the context of chemical evolution, selected templates are employed to facilitate synthesis of complementary RNA sequences. In other work, oligonucleotide sequences are used to direct reactive molecules (warheads) to a complementary target DNA, so as to cleave a crosslink to the target at a predetermined position. Methods for crosslinking transcription factors irreversibly to their DNA recognition sequences are also being developed. His NASA-sponsored research focuses on the catalysis of nucleic acid replication by mineral surfaces.

Orgel wrote THE ORIGINS OF LIFE: MOLECULES AND NATURAL SELECTION (1970)

and co-authored, with Stanley Miller, THE ORIGINS OF LIFE ON THE EARTH (1974). He has published over three hundred articles in his research areas.

Orgel's contributions have been recognized throughout his career. In Britain he was awarded the Harrison Prize in 1957 for his work in inorganic chemistry and elected a Fellow of the Royal Society in 1962. In the United States he received a Guggenheim Fellowship in 1971, the Evans Award from Ohio State University in 1975, and the H.C. Urey Medal from the International Society for the Study of the Origin of Life. He was elected a member of the National Academy of Sciences in 1990.

Scope and Content

The Leslie Orgel Papers document research in nucleic acid chemistry and molecular evolution conducted between 1964 and 1991 at the Chemical Evolution Laboratory of the Salk Institute for Biological Studies. The papers contain correspondence, manuscripts of Orgel's books and journal articles, grants and proposals, conference and meeting material, subject files, Salk Institute files, and referee reports written by Orgel.

The papers are arranged in eight series: 1) BIOGRAPHICAL MATERIAL, 2) CORRESPONDENCE, 3) WRITINGS, 4) CONTRACTS, GRANTS AND PROPOSALS, 5) CONFERENCES AND MEETINGS, 6) SUBJECT FILES, 7) SALK INSTITUTE, and 8) REFEREE REPORTS.

SERIES 1: BIOGRAPHICAL MATERIAL

Arranged alphabetically, the BIOGRAPHICAL MATERIAL series contains Orgel's annotated wall calendars, newspaper clippings and his application for naturalization as a U.S. citizen.

SERIES 2: CORRESPONDENCE

The CORRESPONDENCE series is arranged in four subseries: A) Outgoing Chronological Files, B) General, C) Scientific, and D) Personal.

A) The Outgoing Chronological Files subseries contains copies of outgoing letters (1964-1991).

B) The General subseries contains correspondence associated with routine laboratory business: letters of inquiry regarding possible employment, correspondence with suppliers, requests for visits, and cordial correspondence. In most cases, the incoming letters are accompanied by outgoing replies. The correspondence is arranged chronologically.

C) The Scientific subseries includes correspondence with colleagues and other scientists regarding scientific and technical issues. The materials are arranged alphabetically by author. Prominent correspondents include F.H.C. Crick, Robin Holliday, Jean-Michel Labouygues, Stanley Miller, Carl Sagan, S.A. Seleznev, and Eugene Wigner.

D) The Personal subseries includes letters to and from friends and correspondence related to personal interests, travel plans and projects.

SERIES 3: WRITINGS

The WRITINGS series is organized in two subseries: A) Published, and B) Unpublished.

A) The Numbered Publications subseries, arranged numerically, largely contains research articles and begins with Orgel's numbered chronological list of publications. The folders contain drafts, final versions, correspondence, redacted referee reports, and reprints. The subseries contains 259 of the 302 listed titles, including the draft and correspondence for his textbook entitled TRANSITION METAL CHEMISTRY: LIGAND FIELD THEORY (1960), the only representative from his work while in England. Also included are materials for his other two books, THE ORIGINS OF LIFE: MOLECULES AND NATURAL SELECTION (1973) and, THE ORIGINS OF LIFE ON THE EARTH (1974) with Stanley L. Miller. Of particular interest are Orgel's files for two collaborative articles with Francis Crick, "Directed Panspermia" (#137) and "Selfish DNA: The Ultimate Parasite" (#186), which contain abundant correspondence.

B) The Unpublished subseries contains titles that do not appear on Orgel's publications list.

SERIES 4: CONTRACTS, GRANTS AND PROPOSALS

The series is arranged by sponsoring agency in four subseries: A) National Aeronautics and Space Administration (NASA), B) National Institutes of Health (NIH), C) National Science Foundation (NSF), and D) U.S. Army. Within each subseries the materials are arranged chronologically and, in most cases, include a copy of the proposal or contract, correspondence and summary budget information. The NASA series reflects the development of Orgel's long-term research grant entitled "Models for the Generation of Prebiotic Condensing Agents" and his participation in planning for the 1975 Viking Mars Lander mission.

SERIES 5: CONFERENCES AND MEETINGS

The CONFERENCES AND MEETINGS series in arranged chronologically and begins with several summary lists of meetings that Orgel attended. The conference materials include programs, speaker lists and correspondence.

SERIES 6: SUBJECT FILES

The SUBJECT FILES series begins with material associated with Orgel's research interest on the topic of aging, including drafts of a planned, but never published, book written in collaboration with British colleague Robin Holliday, and correspondence files arranged chronologically. Also included are grant files and material reflecting the Salk Institute's research and presentations on aging.

The remaining subject files contain material about several colleagues and correspondence related to a planned book about the history of the groundbreaking group of RNA researchers who belonged to the RNATIECLUB, a mid-1950's society with twenty members dedicated to unraveling the genetic code. Included are photocopies of correspondence (1953-1962) from George Gamow to James Watson and Alexander Rich.

SERIES 7: SALK INSTITUTE

The SALK INSTITUTE series contains files that document Orgel's association and interaction with the Salk Institute and is arranged in six subseries: A) Chemical Evolution Laboratory, B) Faculty, C) Fellows, D) General, E) Salk Memoranda, and F) Salk Institute Biotechnology/Industrial Associates (SIBIA). Included are numerous reports; memoranda with Jacob Bronowski, Frederic De Hoffman and Edwin Lennox; and, files related to the commercial development of biotechnology research by Orgel and his associates.

SERIES 8: REFEREE REPORTS

The REFEREE REPORTS series contains referee reports by Orgel arranged alphabetically by title of journal or name of agency. Orgel was a referee for BIOCHIMICA ET BIOPHYSICA ACTA, BIOINORGANIC CHEMISTRY, the JOURNAL OF MOLECULAR EVOLUTION, the JOURNAL OF THEORETICAL BIOLOGY, and the National Science Foundation.

Referee reports are restricted until the death of Leslie Orgel.

BIOGRAPHICAL MATERIAL

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11FB-208-01Calendars, 1982 - 1991.
12 Newspaper clippings.
13 United States Department of Justice. Immigration and Naturalization Service. Application for Naturalization, 1989.

CORRESPONDENCE

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Outgoing Chronological Files

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14 1964 January, September-December.
15 1965 January-April.
16 1965 May-August.
17 1965 September-December.
21 1966 January-April.
22 1966 May-July.
23 1966 August-December.
24 1967 January-May.
25 1967 June-December.
26 1968.
27 1969.
28 1970 January-September.
29 1972 February-September.
210 1973 July-October.
211 1975 September-December.
212 1976 March-December.
31 1977.
32 1978.
33 1979 January-April.
34 1979 May-December.
35 1980 January-July.
36 1980 August-December.
37 1981 January-August.
38 1981 September-December.
39 1982 January-June.
310 1982 July-December.
311 1983 January-May.
41 1983 June-December.
42 1984 January-June.
43 1984 July-December.
44 1984 January-February.
45 1985 March-May.
46 1985 June-December.
47 1986 January-September.
48 1986 October-December.
49 1987 January-March.
410 1987 April-July.
51 1987 August-September.
52 1988 January-April.
53 1988 May-August.
54 1988 September-December.
55 1989 January-March.
56 1989 April-July.
57 1989 August-December.
58 1991 January-July.
61 1991 August-December.

General

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62 1964-1966.
63 1967-1969.
64 1970-1974.
65 1975-1977.
66 1978-1985.
67 1986-1989.

Scientific

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71 A - miscellaneous.
72 Altman, Sidney, 1984.
73 American Institute of Biological Sciences, 1973 - 1979.
74 AMERICAN JOURNAL OF HUMAN GENETICS, 1978 - 1980. David E. Comings, editor.
75 AMERICAN SCIENTIST, 1973 - 1979.
76 Arrhenius, Gustaf, 1974 - 1984.
77 ASSOCIATED SCIENTIFIC PUBLISHERS, 1973. F. Suater, Dept. managing director.
78 Avracmides, George, 1982.
79 B - miscellaneous (Ba - Ber).
710 B - miscellaneous (Ber - By).
711 Balasubramanian, R., 1983.
712 Baltscheffsky, Herrick, 1977 - 1978.
713 Ben-Nun, Akiva, 1971 - 1976.
714 Botkin, Daniel B., 1982 - 1983.
715 Brack, Andre, 1977 - 1982.
716 British Broadcasting Corporation, 1976 - 1980.
717 C - miscellaneous.
718 Carmell, L., 1974.
719 Comfort, Alex, 1973 - 1978.
720 Crick, F.H.C., 1965 - 1974.
721 D - miscellaneous.
722 Danielli, James F., 1974 - 1980.
723 Dickerson, Richard E., 1979 - 1981.
724 Dyson, Freeman, 1981.
81 E - miscellaneous.
82 Eirich, F.R., 1984.
83 Encyclopedia of Ignorance (Miranda Weston-Smith), 1974 - 1979.
84 Eschenmoser, A., 1966.
85 F - Miscellaneous.
86 Ferris, James P., 1969 - 1983.
87 G - miscellaneous.
88 Galas, David J., 1973 - 1980.
89 Gallant, Jonathon A., 1977.
810 Gould, Stephen Jay, 1981.
811 Granada Television Limited (Jack Smith, Executive Producer), 1979 - 1980.
812 H - miscellaneous.
813 Hendry, Lawrence B., 1981 - 1983.
814 Holliday, Robin, 1964 - 1978. See also Series 6: Aging.
815 Horowitz, N.H., 1970 - 1984.
816 I - miscellaneous.
817 Idiot papers and comments, 1964 - 1979.
818 International Society for the Study of the Origin of Life, 1989.
819 J - miscallaneous.
820 K - miscellaneous.
821 Kendrew, John C., 1967 - 1975.
822 Khorana, Gobind H., 1969 - 1978.
91 Kornberg, Arthur, 1968 - 1981.
92 L - miscellaneous.
93 Labouygues, Jean-Michel, 1974 - 1982.
94 Lagerkvist, Ulf, 1977 - 1979.
95 Lasser, David, 1981 - 1982. Includes interview with Orgel.
96 Leonard, Nelson, 1988 - 1989.
97 M - miscellaneous.
98 Mandell, Arnold J., 1981 - 1982.
99 Michelson, A.M., 1967 - 1968.
910 Miles, Todd, 1971 - 1983.
911 Miller, Stanley L., 1975 - 1983.
912 Monod, Jacques, 1963 - 1973.
913 N - miscellaneous.
914 National Academy of Sciences, 1990.
915 NATURE (Elizabeth Hughes, publisher), 1981.
916 Neurologische Klinik der Universitat, 1974 - 1975.
917 Ninio, Jacques, 1974 - 1981.
918 O - miscellaneous.
919 Oro, John, 1965 - 1983.
920 P - miscellaneous.
921 Paecht-Horowitz, Mella, 1972.
922 Peters, David, 1981.
923 Phillips, William, 1965 - 1966.
924 Pitha, Josef, 1969 - 1974.
925 Ponnamperuma, Cyril, 1965 - 1970.
926 R - miscellaneous.
927 Rabinowitz, Joseph M., 1969 - 1970.
928 Reese, Colin B., 1981 - 1984.
101 Robins, Roland K., 1968 - 1969.
102 Royal Society, 1970 - 1985.
103 S - miscellaneous (Sa - Sh).
104 S - miscellaneous (Si - Su).
105 Sagan, Carl, 1973 - 1982.
106 Schwartz, Alan W., 1972 - 1981.
107 Seleznev, S. A., 1974 - 1975.
108 Sobell, Henry M., 1965 - 1982.
109 Stein, Gabriel, 1965 - 1968.
1010 Strehler, Bernard L., 1974 - 1981.
1011 T - miscellaneous.
1012 Thaxton, Charles B., 1981 - 1983.
1013 Todd, John H., 1969.
1014 Townes, Charles, 1970 - 1972.
1015 TRENDS IN BIOCHEMICAL SCIENCES, 1975 - 1980. Joan Morgan, staff editor.
1016 Ts'o, Paul O. P., 1968 - 1976.
1017 U - miscellaneous.
1018 Usher, David A., 1975 - 1983.
1019 V - miscellaneous.
1020 Verheyden, Julien P. H., 1983.
1021 W - miscellaneous.
1022 Watson, J. D., 1980.
1023 Wells, Robert D., 1982 - 1984.
1024 Westheimer, Frank H., 1970 - 1984.
111 Wigner, Eugene P., 1963 - 1970.
112 Worth Publishers, Inc., 1973.
113 Y - miscellaneous.
114 Z - miscellaneous.
115 Z - Miscellaneous.
116 Zubay, Geoffrey, 1979.
117 Unidentified correspondents.

Personal

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118 1971.
119 1972-1975.
1110 1976-1981.
1111 1982-1987.
1112 1988-1992.

Name, A-Z

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WRITINGS

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Published

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1113 List of publications, 1951 - 1997.
1114 61 - INTRODUCTION TO TRANSITION METAL CHEMISTRY: LIGAND FIELD THEORY, 1960.
1115 87 - Induction of Mutations in Bacteriophage T4 with Divalent Manganese, 1965.
1116 89 - Reactions of Bromomalononitrile with Bases, 1965.
1117 90 - Formation of Condensed Phosphate in Aqueous Solution, 1965.
121 91 - Aminomalononitrile and 4-Amino-5- Cyanomidazole in Hydrogen Cyanide Polymerization and Adenine Synthesis, 1965.
122 93 - Photochemical Synthesis of Condensed Phosphates, 1965.
123 94 - An Unusual Photochemical Rearrangement in the Synthesis of Adenine from Hydrogen Cyanide, 1966.
124 95 - Conditions for Purine Synthesis: Did Prebiotic Synthesis Occur at Low Temperatures?, 1966.
125 96 - Studies in Prebiotic Synthesis I. Aminomalononitrile and 4-Amino-5-Cyanomiclazole, 1966.
126 97 - Cyanoacetylene in Prebiotic Synthesis, 1966.
127 101 - Nucleoside Synthesis Under Potentially Prebiotic Conditions, 1967.
128 103 - Studies in Prebiotic Synthesis. II. Synthesis of Purine Precursors and Amino Acids from Aqueous..., 1967.
129 104 - The Non-Enzymatic Synthesis of Deoxyadenylate Oligonucleotides on a Polyuridylate Template, 1968.
1210 105 - Studies in Prebiotic Synthesis. III. Synthesis of Pyrimidines from Cyanoacitylene and Cyanate, 1968.
1211 106 - Specificity of Oligonucleotide Synthesis Directed by Polyuridylic Acid, 1968.
1212 107 - Prebiotic Synthesis: Phosporylation in Aqueous Solution, 1968.
1213 108 - Template-Directed Synthesis with Adenosine-5'-Phosphorimidazolide, 1968.
1214 109 - Non-Enzymic Synthesis of Deoxyadenulate Oligonucleotides on a Polyuridylate Template, 1968.
1215 110 - Studies in Prebiotic. IV. The Conversion of 4-Aminoinidazole-5-Carbonitrile Derivatives to Purines, 1968.
1216 111 - Partial Resolution of DL-Adenosine by Template Synthesis, 1968.
1217 112 - Evolution of the Genetic Apparatus, 1968.
1218 114 - Non-Enzymic Oligonucleotide Synthesis on a Polytidylate Template, 1969.
1219 115 - Phosphorylation of D-Ribose in Aqueous Solution, 1969.
1220 116 - Specificity of Template-Directed Synthesis with Adenosine Nucleotides, 1970.
1221 117 - Studies in Prebiotic Synthesis. V. Synthesis and Photoanomerization of Pyrimidine Nucleosides, 1970.
1222 119 - In Vitro Selection of QB Ribonucleic Acid Variants Resistant to Ethidium Bromide, 1970.
1223 120 - Prebiotic Synthesis of Propiolaldehyde and Nicotinamide, 1970.
1224 121 - The Maintenance of the Accuracy of Protein Synthesis and Its Relevance to Ageing: A Correction, 1970.
1225 122 - Template Catalysis of Acetyl Transfer Reactions, 1971.
1226 123 - Urea-Inorganic Phosphate Mixtures as Prebiotic Phosphorylating Agents, 1971.
1227 124 - The Mechanism of the Trimetaphosphate-Induced Peptide Synthesis, 1971.
131 125 - Catalysts for the Polymerization of Adenosine Cyclic 2',3'-Phosphate on a Poly(U) Template, 1971.
132 128 - Prebiotic Phosphorylation of Thymidine at 65 Degrees Centigrade in Simulated Desert Conditions, 1972.
133 129 - Studies in Prebiotic Synthesis. VI. Synthesis of Nucleosides, 1972.
134 130 - Polyphosphate and Trimetaphosphate Formation Under Potentially Prebiotic Conditions, 1972.
135 131 - Studies in Prebiotic Synthesis. VII. Solid-State Synthesis of Purine Nucleosides, 1972.
136 132 - A Possible Step in the Origin of the Genetic Code, 1972.
137 133 - THE ORIGINS OF LIFE: MOLECULES AND NATURAL SELECTION, 1973.
138 133 - THE ORIGINS OF LIFE: MOLECULES AND NATURAL SELECTION, 1973. Figures and photographs (part 1).
139 133 - THE ORIGINS OF LIFE: MOLECULES AND NATURAL SELECTION, 1973. Figures and photographs (part 2).
1310 134 - Struvite and Prebiotic Phosporylation, 1973.
1311 135 - An RNA that Multiplies Indefinitely with DNA-Dependent RNA Polymerase: Selection from a Random Copolymer, 1973.
1312 136 - Further Studies of Urea-Catalyzed Phosphorylation Reactions, 1973.
1313 137 - Directed Panspermia, 1973.
1314 137 - Directed Panspermia, 1973. Correspondence.
1315 139 - Ageing of Clones of Mammalian Cells, 1973.
141 140 - Prebiotic Activation Processes, 1973.
142 141 - The Effect of Mg2+ and Ca2+ on Urea-Catalyzed Phosphorylation Reactions, 1973.
143 142 - Catalysts for the Self-Polymerization of Adenosine Cyclic 2',3'-Phosphate, 1973.
144 143 - Analysis of High Molecular Weight Material from the Polymerization of Adenosine Cyclic 2',3'-Phosphate, 1974.
145 144 - THE ORIGINS OF LIFE ON THE EARTH, 1974.
146 145 - On the Possible Role of Crystals in the Origins of Life. VII. The Adsorption and Polymerization..., 1974.
147 146 - Sedimentary Minerals Under Reducing Conditions, 1974.
148 147 - Prebiotic Chemistry and Nucleic Acid Replication, 1974.
149 149 - Poly(U)-Directed Transamidation Between Adenosine 5'-Phophorimidazolide and ..., 1974.
1410 150 - Oligonucleotide Synthesis Catalyzed by the Zn2+ Ion, 1975.
1411 151 - Prebiotic Peptide-Formation in the Solid State, 1975.
1412 152 - Triple Helices Formed by Polyuridylic Acid With Some Adenosine Derivatives, 1975.
1413 153 - Prebiotic Peptide-Formation in the Solid State. II. Reaction of Glycine with Adenosine..., 1975.
1414 154 - Prebiotic Peptide-Formation in the Solid State. III. Condensation Reactions of Glycine in Solid..., 1975.
1415 155 - (Beta) Structure of Alternating Polypeptides and Their Possible Prebiotic Significance, 1975.
1416 156 - Prebiotic Polynucleotides and Polypeptides, 1975.
1417 158 - N,N-Carbonyldiimidazole-Induced Peptide Formation in Aqueous Solution, 1976.
1418 159 - Polymerization of Nucleotide Analogues I: Reaction of Nucleoside 5'-Phosphorimidazolides..., 1976.
1419 160 - Tenokate-Directed Synthesis of High Molecular Weight Polynucleotide Analogues, 1976.
1420 161 - Triple Helices Formed by Polyuridylic Acid with Some Amino Deoxyadenosine Derivatives, 1976.
1421 162 - Search for Organic and Volatile Inorganic Compounds in Two Surface Samples from the Chryse Planitia..., 1976.
1422 163 - N,N-Carbonyldiimidazole-Induced Deketopiperazine Formation in Aqueous Solution in the Presence..., 1976.
1423 164 - Some 5'-Azido and 5'-Amino-2'-Deoxyribonucleotides, Their 3'-Phosphates and Their..., 1976.
1424 165 - Reactions of Polyfunctional Amino Acids with N',N'-Carbonyldiimidazole in Aqueous Solution..., 1977.
151 166 - (Beta)-Turns and the Evolution of Protein Synthesis, 1977.
152 167 - Reactions of Adenosine 5'-Phosphorimidazolide with Adenosine Analogs on a Polyuridylic Template, 1977.
153 168 - Template-Directed Reactions of Aminonucleosides, 1977.
154 169 - Gene Duplication and the Origin of Proteins with Novel Functions, 1977.
155 170 - The Search for Organic Substances and Inorganic Volatile Compounds in the Surface of Mars, 1977.
156 171 - Template-Directed Polynucleotide Condensation as a Model for RNA Replication, 1978.
157 172 - Preferential Formation of (2'-5')-Linked Internucleotide Bonds in Non-Enzymatic Reactions, 1978.
158 173 - Formation of P1,P2-Dinucleoside 5'-Pyrophosphates Under Potentially Prebiological Conditions, 1978.
159 174 - Amino Acid Activation with Adenosine 5'-Phosphorimidazole, 1978.
1510 175 - Phosporylation of Nucleosides in Aqueous Solution Using Trimetaphosphate: Formation of Nucleoside..., 1978.
1511 176 - Formation of the Imidazolides of Dinucleotides Under Potentially Prebiotic Conditions, 1978.
1512 177 - The Formation of Peptides from the 2'(3')-Glycyl Ester of a Nucleotide, 1978.
1513 178 - Heteropolynucleotides as Templates for Non-Enzymatic Polymerizations, 1978. A prior version titled "Template-Directed Condensation in Oligoadenylic Acids" is located in Series 3B.
1514 179 - Studies of Oligoadenylate Formation on a Poly(U) Template, 1979.
1515 180 - The Catalysis of Nucleotide Polymerization by Compounds of Divalent Lead, 1979.
1516 181 - Selection In Vitro, 1979.
1517 182 - The Formation of Dipeptides from Amino Acids and the 2'(3')-Glycyl Ester of an Adenylate, 1979.
1518 183 - The Formation of Peptides from Glycine Thioesters, 1979.
1519 184 - Template-Directed Synthesis of Oligoadenylates Catalyzed by Pb2+ Ions, 1979.
1520 185 - Self-Condensation of Activated Dinucleotides on Polynucleotide Templates with Alternating Sequences, 1979.
161 186 - Selfish DNA: The Ultimate Parasite, 1980.
162 186 - Selfish DNA, 1980. Correspondence: February - May.
163 186 - Selfish DNA, 1980. Correspondence: June - October.
164 188 - Efficient Metal-Ion Catalyzed Template-Directed Oligonucleotide Synthesis, 1980.
165 189 - Template-Directed Synthesis and Selective Adsorption of Oligoadenylates on Hydroxyapatile, 1980.
166 190 - Poly(U)-Directed Peptide Bond Formation from the 2'(3')-Glycyl Ester of Adenosine Derivatives, 1980.
167 191 - Efficient Catalysis of Polycytidylic Acid-Directed Oligoguanylate Formation by Zn2+, 1980.
168 192 - Catalysis of Accurate Poly(C)-Directed Synthesis of 3'-5'-Linked Oligoguanylates by Zn2+, 1980.
169 193 - Template-Directed Synthesis of Oligoguanylic Acids - Metal Ion Catalysis, 1981.
1610 194 - Template-Directed Synthesis of Oligoguanylates in the Presence of Metal Ions, 1980.
1611 196 - The Effect of Poly(C) on the Formation of Peptide Bonds from the 2'(3')-Gycyl Ester of a Guanosine..., 1981.
1612 197 - Synthesis of Oligoguanylates on Oligocytidylate Templates, 1981.
1613 198 - Condensation of Activated Diguanylates on a Poly(C) Template, 1981.
1614 199 - Substituent Control of the Poly(C)-Directed Oligomerization of Guanosine 5'..., 1981.
1615 200 - Template-Directed Reactions of 2-Aminoadenylic Acid Derivatives, 1982.
1616 201 - Oligomerization of (Guanosine 5'-Phosphor)-2-Methylimidazolide on Poly(C): An RNA Polymerase..., 1982.
1617 202 - Darwinism At the Very Beginning of Life, 1982.
1618 203 - A Non-Enzymatic RNA Polymerase Model, 1983.
1619 204 - The Origin of Life and the Evolution of Macromolecules, 1983.
171 205 - Derivation of Unprotected Polynucleotides, 1983.
172 206 - Temperature-Dependence of the Template-Directed Synthesis of Oligoguanylates, 1984.
173 207 - Preparation of Ligation Intermediates and Related Polynucleotide Pyrophosphates, 1984.
174 208 - Non-Enzymatic Template-Directed Synthesis on RNA Random Copolymers: Poly(C,U) Templates, 1984.
175 209 - Chiral Selection in Poly(C)-Directed Synthesis of Oligo(G), 1984.
176 210 - Template-Directed Synthesis on the Pentanucleotide CpCpGpCpC, 1984.
177 211 - Template-Directed Synthesis with 2-Aminoadenosine, 1984.
178 212 - Non-Enzymatic Sequence-Specific Cleavage of Single-Stranded DNA, 1985.
179 213 - Oligomerization of Activated Derivatives of 3'-Amino-3'-Deoxyguanosine on Poly(C) and Poly(dC)..., 1985.
1710 214 - Template-Directed Synthesis of Oligodeoxycytidylate and Polydeoxycytidylate Templates, 1980.
1711 215 - Template-Directed Synthesis of Novel, Nucleic Acid-Like Structures, 1985.
1712 217 - Template-Directed Polynucleotide Synthesis on Mineral Surfaces, 1985. Letter to the editor.
1713 218 - Detection of Specific DNA Sequences with Short Biotin-Labeled Probes, 1985.
181 220 - Template-Directed Synthesis on the Oligonucleotide d(C7GC7), 1986.
182 221 - Non-Enzymatic Template-Directed Synthesis on RNA Random Copolymers: Poly(C,G) Templates, 1986.
183 222 - Template Properties of Some Oligodeoxynucleotides Containing Cytidine and Guanosine, 1986.
184 223 - Template-Directed Oligonucleotide Ligation on Hydroxylapatite, 1986.
185 224 - Synthesis of an Amplifiable Reporter RNA for Bioassays, 1986.
186 225 - Molecular Replication and the Origins of Life, 1986.
187 226 - Template-Directed Synthesis on Short Oligoribocytidylates, 1986.
188 227 - How Mistakes Are Made, 1986.
189 228 - Did Template-Directed Nucleation Precede Molecular Replication?, 1986.
1810 229 - Mini-Review. RNA Catalysis and the Origins of Life, Part 1, 1986.
1811 229 - RNA Catalysis and the Origins of Life, Part 2, 1986.
1812 230 - Oligoaminonucleoside Phosphoramidates. Oligomerization of Dimers of 3'-Amino-3', 1987.
1813 231 - Action of a Water-Soluble Carbodiimide on Adenosine-5'--Polyphosphates, 1987.
191 232 - Autocatalytic Synthesis of a Tetranucleotide Analogue, 1987.
192 233 - Oligomerization of 3'-Amino-3'-Deoxyguanosine-5'-Phosphorimidazolidate...
193 234 - A Case for an Ancestral Genetic System Involving Simple Analogues of the Nucleotides, 1987.
194 235 - Impressions: LII Cold Spring Harbor Symposium on Quantitative Biology, the Evolution of Catalytic..., 1987.
195 236 - Non-Enzymatic Transcription of an Oligodeoxynucleotide 14 Residues Long, 1987.
196 237 - Evolution of the Genetic Apparatus: A Review, 1987.
197 238 - The Origin of Self-Replicating Molecules, 1987.
198 239 - Template-Directed Oligomerization of 3-Isoadenosine 5'-Phosphate, 1988.
199 240 - Ligation of Oligonucleotides to Nucleic Acids or Proteins Via Disulfide Bonds, 1988.
1910 241 - Non-Enzymatic Template-Directed Synthesis on RNA Random Copolymers: Poly(C,A) Templates, 1988.
1911 242 - Cyclization of Nucleotide Analogues as an Obstacle to Polymerization, 1989. Letter to the editor.
1912 243 - Some Acyclic Analogues of Nucleotides and Their Template-Directed Reactions, 1989.
1913 245 - Reaction on Alternating GC Oligonucleotide Templates, 1989.
1914 246 - Replacement of the 3'-CH Group by Nitrogen in the Carbolic Analogue of Thymidine, 1989.
1915 247 - Was RNA the First Genetic Polymer?, 1989.
201 248 - Template Properties of Tetranucleoside Triphosporamidates Having Cytosine-Guanosine Residues, 1989.
202 249 - Polymerization of a Momeric Guanosine Derivative in a Hydrogen-Bonded Aggregate, 1989.
203 250 - The Origin of Polynucleotide-Directed Protein Synthesis, 1989.
204 251 - Polymerization of the Cyclic Pyrophosphates on Nucleosides and Their Analogues, 1990.
205 Between 251 and 252 - Nucleic Acids: Adding to the Genetic Alphabet, 1990.
206 252 - A Simple Procedure for Cross-Linking Complementary Oligonucleotides, 1990.
207 253 - Polymerization of Amino Acids Containing Nucleotide Bases, 1990.
208 255 - Blunt-End and Single-Strand Ligations by Escherichia Coli Ligase: Influence on an In Vitro..., 1990.
209 257 - Synthesis of 5'-Deoxy-5'-Nucleosideacetic Acid Derivatives, 1990.
2010 258 - Pyrophosphate-Formation As the Most Efficient Condensation Reaction of Activated Nucleotides, 1991.
2011 259 - Disulfide-Linked Oligonucleotide Phosphothioates: Novel Analogues of Nucleic Acids, 1991.
2012 260 - Acceleration of the Template-Directed Reactions of Nucleoside 5'-Phosphorimidazolides by Acylation, 1991.
2013 261 - The Cyclization of Arabinosyladenine-5'-Phosphorimidazolide, 1991.
2014 262 - Which 3-Ribofuranosyl-Substituted Purine 5'Phosphates Undergo Template-Directed Oligomerization?, 1991.
2015 263 - Template-Directed Extension of a Guanosine 5'Phosphate Covalently Attached to an Oligodeoxycytidylate..., 1991.
2016 264 - The Photooxidation of Oligodeoxynucleotides by UO2 2+, 1991.
211 265 - Efficient Sequence-Specific Method for Crosslinking Complementary Oligonucleotides Using Binuclear..., 1991.

Unpublished

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212 Existence of Self-Reproducing Units.
213 Oligomerization of Dimers of 3'-Amino-3'-Deoxynucleotides Having Complementary AC and GU Sequences.
214 Poly(dC) as a Template for Non-Enzymatic Oligo(G) Synthesis.
215 Polymerization of a Monomeric Guanosine Derivative in a Hydrogen Bonded Aggregate.
216 Template-Directed Condensation of Oligoadenylic Acids, Part 1. The published version of this paper is located in Series 3A: 178 - Heteropolynucleotides as Templates for Non-Enzymatic Polymerizations.
217 Template-Directed Condensation of Oligoadenylic Acids, Part 2.
218 Thermal Synthesis of Oligourdylates at Moderate Temperatures.

CONTRACTS, GRANTS AND PROPOSALS

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National Aeronautics and Space Administration

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2110 1969: Photochemical Generation of Prebiotic Condensing Agents.
2111 1970: Models for the Generation of Prebiotic Condensing Agents.
2112 1970: Participation in the Science Planning for the Viking 1975 Missions in the Area of Molecular Analysis.
2113 1971: Models for the Generation of Prebiotic Condensing Agents.
221 1971: Participation in the Science Planning for the Viking 1975 Missions in the Area of Molecular Analysis.
222 1972-1980: Participation in the Science Planning for the Viking 1975 Missions in the Area of Molecular...
223 1972: Models for the Generation of Prebiotic Condensing Agents.
224 1973: Models for the Generation of Prebiotic Condensing Agents.
225 1974: Models for the Generation of Prebiotic Condensing Agents.
226 1975: Models for the Generation of Prebiotic Condensing Agents.
227 1976: Models for the Generation of Prebiotic Condensing Agents.
228 1977: Models for the Generation of Prebiotic Condensing Agents.
229 1978: Models for the Generation of Prebiotic Condensing Agents.
2210 1982: Models for the Generation of Prebiotic Condensing Agents.
2211 1982: RNA Polymerase Models.
2212 1983: Models for the Generation of Prebiotic Condensing Agents.
2213 1984: Models for the Generation of Prebiotic Condensing Agents.
231 1985: Models for the Generation of Prebiotic Condensing Agents.
232 1985: Prebiotic Template-Directed Synthesis.
233 1986: Models for the Generation of Prebiotic Condensing Agents.
234 1987: Models for the Generation of Prebiotic Condensing Agents.
235 1988: Models for the Generation of Prebiotic Condensing Agents.

National Institutes of Health

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236 1965-1966: Evolution of Genetic Specificity.
237 1967-1968: Evolution of Genetic Specificity.
238 1971-1974: Nucleic Acid Analogs - Synthesis and Chemotherapy.
241 1975: Evolution of Genetic Specificity.
242 1976-1977: Evolution of Genetic Specificity.
243 1982-1984: Evolution of Genetic Specificity.
244 1985-1987: Evolution of Genetic Specificity.

National Science Foundation

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245 1964-1965: Study of Biochemical Evolution.
246 1966-1969: Study of Biochemical Evolution.
247 1973-1978: Prebiotic Activation of Amino Acids and Nucleotide Bases.
251 1978-1979: Prebiotic Formation of Peptide Bonds.
252 1981-1983: A Non-Classical System of Template-Directed Synthesis.
253 1982-1984: Template-Directed Synthesis with 3'-Amino 3'-Deoxynucleotides.
254 1985-1986: Template-Directed Synthesis with 3'-Amino 3'-Deoxynucleotides.
255 1987-1989: Template-Directed Synthesis with 3'-Amino 3'-Deoxynucleotides.

United States Army

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256 1985-1986: Sequence-Specific Inactivation of m-RNA.

CONFERENCES AND MEETINGS

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257 Lists of meetings attended: 1975-1977, 1981-1985.
258 1971 September 5-11: First Soviet American Conference on Communication with Extraterrestrial Intelligence... 1967 October 20: A series of "Telesnaps" photographs from a British Broadcasting Corporation program, numbered.
259 1973 May 28: Quatrieme Conference Internationale de la Physique Theorique a la Biologie.
2510 1975 February 27-28: Some Aspects of Pre-Biotic Chemistry - Some Theories of Ageing (and the Evidence).
2511 1975 March 2-7: Symposium on Nucleic Acid Replication.
2512 1975 March 23-25: Fourth Annual Workshop on the Biology of Aging - Perspectives in Theories of Biological...
2513 1975 May 23: Polymerization and Polycondensation on Clays - Their Role in Abiotic Synthesis and the Origin...
261 1975 May 26-28: European Molecular Biology Organization. Workshop, Part 1.
262 1975 May 26-28: European Molecular Biology Organization. Workshop, Part 2. Contains letters by Carl Sagan (1/17/75) and Severo Ochoa (11/21/74).
263 1975 August 7-11: Viking Science Symposium on Earth and Mars - The Role of Life.
264 1975 August 13: Prebiotic Synthesis of Nucleotides and Polynucleotides.
265 1975 October 22: Chemistry Colloquium, Department of Chemistry. Purdue University.
266 1975 October 24: Evans Lecture. Ohio State University. Chemistry Department.
267 1975 October 28: Towards Self-Replicating Molecules. Texas A and M University. College of Agriculture.
268 1975 October 29-31: Robert A. Welch Foundation Conferences on Chemical Research. XIX Photon Chemistry.
269 1975 November 19: Bio-Cultural Concepts of Man.
2610 1975 December 3-4: Discussion Colloquium on the Biology of Religion.
2611 1976 January 25-30: Gordon Research Conference on the Biology of Aging.
2612 1976 February 6: Lectures on Chemical Evolution. Stanford University Medical Center.
2613 1976 February 18-24: Science and Our Expectations - Bicentennial and Beyond. Contains letter by Carl Sagan (10/17/75).
2614 1976 March 18-19: Viking Molecular Analysis Team.
2615 1976 April 6: Genetics Seminar, Salk Institute - Origin of Self-Replicating Material.
2616 1976 April 9-10: Viking Project. Jet Propulsion Laboratory - Viking Flight Team Memorandum.
2617 1976 April 19-20: Renaud Lectures. Michigan State University. Department of Biochemistry.
2618 1976 May 3-6: Organization and Expression of the Eukaryotic Genome.
2619 1976 June 28: Langley Colloquium Series.
2620 1977 January 10-12: Present State of Viking Data. MIT. Department of Chemistry.
2621 1977 January 20-22: Institute for Higher Studies Seminar - A Fifty Year View.
2622 1977 March 3-4: United States Information Agency. Viking Science Tour.
2623 1977 March 14: New Trends in Geriatric Care. UC San Diego, School of Medicine.
2624 1977 April 19-20: Molecules and Evolution. International Lectures on Human, Global and Universal Problems.
2625 1977 March 29: Origin of Self-Replicating Molecules. California State University, Los Angeles.
2626 1977 May 16: Origins of Life Festival. University of Oregon. Institute of Molecular Biology.
2627 1977 June 28-29: Viking Science Steering Group Meeting.
2628 1977 July 15-16: Current Biological Problems - A School for Physical Scientists.
2629 1977 August 21 - September 3: International Summer School on Genome Organization and Function.
2630 1977 October 17: Seminar. California Institute of Technology. Division of Biology.
2631 1977 November 8: A Conversation About the Origins of Life.
271 1977 November 16: Seminar Series. California State University, Long Beach. Department of Chemistry.
272 1977 December 1: Science Seminar. San Diego City College. Department of Chemistry.
273 1978 December 6-7: Meeting of the Royal Society.
274 1979 August 26-31: Conference on Selforganization in Living Systems.
275 1979 October 25-26: The Evolution of Life - a Public Symposium.
276 1980 January 17-18: Fifth Science Workshop on the Origins of Life.
277 1980 February 4-5: American Institute of Biological Sciences. Planetary Biology Advisory Panel.
278 1980 April 18: Prebiotic Chemistry - Nucleic Acids and the Origin of Self-Replication.
279 1980 April 24-25: Science Workshops on the Origins of Life.
2710 1980 May 20-21: Monsanto Company Technical Management Conference - New Technology Horizons.
2711 1980 June 16-17: Workshop on Molecular Evolution and Function of Three Dimensional Structure in Nucleic...
2712 1980 June 23-27: International Society for the Study of the Origins of Life Conference.
2713 1980 September 25: Pomona College Dreyfus Seminar Series.
2714 1980 September 30: Seminar. Massachusetts Institute of Technology.
2715 1981 February 28: Cal Tech Centennial Symposium - The Chemical Bond Structure and Dynamics.
2716 1981 March 4: Towards an RNA Polymerase Model.
2717 1981 March 31: Contemporary Issues Undergraduate Seminar. Origins of Life in the Ocean? Held at UCSD.
2718 1981 June 22-24: Genome Evolution and Phenotype Variation. Cambridge Genome Meeting.
2719 1981 July 12-15: Dalhousie Symposium on the Evolution of the Eukaryotic Genome and Its Components.
2720 1981 August 3-4: Organizing and Planning Meeting for Workshops on Exobiology in the Exploration...
2721 1981 September 1-6: European Molecular Biology Organization Workshop on Accuracy.
2722 1981 September 6-9: Max Planck Institute.
2723 1981 October 24-25: California Catalysis Society Fall Meeting.
2724 1981 December 7-8: Committee on Planetary Biology and Chemical Evolution - Space Science Board.
2725 1981 December 9-11: Workshop on Exobiology in Solar System Exploration.
2726 1982 February 2: City of Hope Research Institute Seminar.
2727 1982 February 8-12: Gordon Conference on Metals in Biology.
2728 1982 March 16: Biophysical/Physical Chemistry Seminar. U.C. Berkeley. Chemistry Department.
2729 1982 March 20: Life Sciences Advisory Committee Meeting. Exobiology Program Review.
2730 1982 March 25-28: Space Science Board. Committee on Planetary Biology and Chemical Evolution.
2731 1982 April 12: Exobiology Program Review.
2732 1982 April 28: Origin and Evolution of Life. Tufts University. Sackler School of Graduate Biomedical Sciences.
2733 1982 May 17-June 3: Committee on Space Science Research, 24th Plenary Meeting. Chemical Evolution...
281 1982 June 27-July 2: Darwin Centenary Conference.
282 1982 July 19-23: Gordon Conference on the Origin of Life.
283 1982 August 2-4: First Symposium on Chemical Evolution and the Origin and Evolution of Life.
284 1982 August 26-September 1: The Past, Present and Future of Genetics.
285 1982 September 5-10: Nobel Symposium on Inorganic Biochemistry.
286 1982 December 10-12: U.S. -Japan Cooperative Seminar on Pathogenic Mechanisms in Werner's Syndrome...
287 1983 February 22: Gerontology Research Center Seminar. A Non-Enzymatic RNA Polymerase Model.
288 1983 February 23-25: Space Science Board. Committee on Planetary Biology.
289 1983 May 26-31: American Association for the Advancement of Science. Science and Engineering - Toward a...
2810 1983 July 10-15: 7th International Conference on the Origins of Life and 4th Meeting of the International...
2811 1983 August 25-26: Third Workshop on Exobiology in Solar System Exploration.
2812 1983 September 19-20: Conference on Biomaterials.
2813 1983 October 14: Attempts to Imitate RNA Polymerase. University of Southern California.
2814 1983 October 18: Attempts to Develop a Nonenzymatic RNA Polymerase. California State University, Los Angeles.
2815 1983 October 26-28: Pacific Conference on Chemistry and Spectroscopy. Origin of Life Symposium.
2816 1985 February 7: Organization, Replication and Evolution of Early Macromolecules.
2817 1985 February 13: Chemische Gesellschaft Zurich.
2818 1985 April 12: City of Hope.
2819 1985 May 2-4: Discussion on Primary Structure Conformation and Evolution of Nucleic Acids and...
2820 1985 June 4-8: Fourth Conversation in the Discipline. Biomolecular Stereodynamics. State Univ. of New York.
2821 1985 July 23-26: 2nd Symposium on Chemical Evolution and the Origin and Evolution of Life.
2822 1985 October 4-7: Niels Bohr Centenary Symposium.
2823 1985 October 14-15: Symposium on the Origin of Life. Contains photograph of birthday cake, "70 Happy Birthday Norm 70."
2824 1985 November 12: Seminar Program. Univ. of California, Davis. Department of Zoology.
2825 1985 November 22-26: Annual Meeting of the Gerontology Society of America. Symposium.
2826 1986 May 15: 50th Anniversary Symposium. A Molecular View of Evolution.
2827 1987 January 18-30: 22nd Winter Seminar on Molecules, Information and Memory.
2828 1987 February 17: Biochemistry Department Lecture Series. University of California, Berkeley.
2829 1987 March 4-7: Western Winter Workshop on the Evolution of Genes and Genomes.
2830 1987 April 28: General Biology Seminar. California Institute of Technology. Division of Biology.
2831 1987 May 4: Significance of Chemical Templates in Studies on the Origin of Life. University of Toledo.
2832 1987 May 27-June 3: Cold Spring Harbor. Evolution of Catalytic Function. Includes letter by James Watson, 10/11/86.
291 1987 June 18-19: Symposium on the Bioorganic Chemistry of Enzymes and Nucleic Acids.
292 1987 June 21-26: Space Life Sciences Symposium. Three Decades of Life Science Research in Space.
293 1987 August 17-21: Gordon Conference on the Origins of Life.
294 1987 September 21-25: Artificial Life - an Interdisciplinary Workshop on the Synthesis and Simulation...
295 1987 November 19-26: The Frontiers of Tomorrow in Biology.
296 1988 January 14-15: Gunter Sachs Postdoctoral Winter Symposium. Genes and Development.
297 1988 February 12-14: American Academy of Sciences.
298 1988 April 14-15: Royal Netherlands Chemical Society. Biennial Symposium of the Organic Division.
299 1988 April 22: 9th Annual D.G. Davis Memorial Lecture. Molecular Replication and the Origin of Life.
2910 1988 July 4-8: Gordon Conference on Enzymes, Coenzymes and Metabolic Pathways.
2911 1988 September 1-10: International Summer School on Organization and Function of the Eukaryotic Genome.
2912 1988 September 25-30: 196th American Chemical Society Meeting and Exposition.
2913 1988 October 24: Template-Directed Synthesis of Oligonucleotides. University of California, Santa Cruz.
2914 1989 March 27-31: Applied Molecular Evolution and the Maturation of the Immune Response.
2915 1989 April 16-19: Ida Bean Visiting Professor Lecture Series. University of Iowa.
2916 1989 May 8-11: Storer Life Sciences Symposium. Evolution of the Biosphere.
2917 1989 May 17-21: Cold Spring Harbor RNA Processing Meeting.
2918 1989 July 3-8: 6th Intl. Society for the Study of the Origin of Life Meeting and 9th Intl. Conference on the...
2919 1990 January 21-26: 25th Winter Seminar on Molecules, Information and Memory.
2920 1990 February 4-8: Frontiers in Biomedical Research.
2921 1990 February 9: Lecture Series on Frontiers in Chemistry. Research Institute of Scripps Clinic.
2922 1990 March 5: Juan March Foundation Lectures on Molecular Biology.
2923 1990 March 28: Biology Department Seminar. Yale University.
2924 1990 July 15-18: Molecular Biology and the Origin of Life Symposium.
2925 1990 July 24-27: 4th Symposium on Chemical Evolution and the Origin and Evolution of Life.
301 1990 October 21-24: Catalytic RNA as an Anti-HIV Agent. Design and Delivery to Cells.
302 1990 November 19: Structural Biology Seminar. University of California, Berkeley. Chemistry Department.
303 1991 February 2-8: Keystone Symposia on Molecular and Cellular Biology.
304 1991 February 28: Tribute to Linus Pauling on His 90th Birthday.
305 1991 April 22: Evolution.
306 1991 May 18: Bruno Zimm Symposium. University of California, San Diego.
307 1991 May 29: American Chemical Society, San Diego Section.

SUBJECT FILES

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308 Aging. Book on Aging - Clonal Aging.
309 Aging. Book on Aging - Drafts.
3010 Aging. Correspondence - 1970, 1972.
3011 Aging. Correspondence - 1973.
3012 Aging. Correspondence - 1974. Contains letter by Jacob Bronowski, 5/8/1974
3013 Aging. Correspondence - 1975.
3014 Aging. Correspondence - 1976-1981.
311 Aging. Correspondence - 1984.
312 Aging. Correspondence with publishers - 1973-1976.
313 Aging. Grant. Draft application to Fritz B. Burns Foundation, 1983.
314 Aging. Grant. McConnell-Clark Foundation grant, 1974-1975.
315 Aging. Grant. National Institute of Health grant - 1972-1973, refused.
316 Aging. Salk Institute. Research programs in aging, 1973.
317 Aging. Salk Institute. Workshops and symposium on aging research - 1973-1974.
318 Biebricher, Christof, 1972-1976.
319 Griffith, John Stanley, 1969. Correspondence regarding candidature for the Royal Society.
3110 Mars photographs.
3111 Mulliken, Robert S., 1978-1985.
3112 RNA sequencing. Reel-to-reel audiorecording.
3113 RNATIECLUB book materials. Includes correspondence (1953-1962) from George Gamow to James Watson and Alexander Rich. Also includes a detailed table of contents.
3114 Sagan, Carl, 1991. Correspondence regarding Sagan's nomination to the National Academy of Sciences.
321 University of California, San Diego. Chemistry Department.

SALK INSTITUTE

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Chemical Evolution Laboratory

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322 Chemical Evolution Laboratory - Annual Report, 1975.
323 Chemical Evolution Laboratory - Annual Report, 1976.
324 Chemical Evolution Laboratory - Annual Scientific Reports, 1977-1980.

Faculty

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325 Faculty Meetings, 1984-1986.
326 Senior Resident Faculty Meetings, 1976-1982.

Fellows

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327 Annual Report of the Director to the Fellows, 1971.
328 Annual Report of the Director to the Fellows, 1975.
329 Fellows Committee, 1970.
3210 Operating Committee - Meeting minutes, 1970.
331 Resident Members of the Committee of Fellows - Meeting minutes, 1965.
332 Space Committee, 1977.

General

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333 Sloan Grant, 1970.
334 Report of Laboratory and Research Activities, 1975.
335 Report of Laboratory and Research Activities, 1977.
336 Report on Laboratory Staffing and Publications, 1976.

Salk Memoranda

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337 Bronowski, Jacob, 1967-1974.
341 De Hoffman, Frederic, 1970-1971.
342 De Hoffman, Frederic, 1972.
343 De Hoffman, Frederic, 1973-1977.
344 De Hoffman, Frederic, 1978-1980.
345 De Hoffman, Frederic, 1981.
346 De Hoffman, Frederic, 1982.
347 Lennox, Edwin L., 1965-1974.
348 Salk Business, 1965-1971.
351 Salk Business, 1972-1975.

Salk Institute Biotechnology/Industrial Associates

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352 Consultant Nonstatutory Stock Option Agreement.
353 SIBIA, 1981.
354 SIBIA, 1982.
355 SIBIA, 1983.
356 SIBIA, 1984.
357 SIBIA, 1985.
358 SIBIA, 1986.
361 SIBIA, 1987.
362 SIBIA, 1988.

REFEREE REPORTS

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371 BIOCHIMICA ET BIOPHYSICA ACTA, 1970 - 1973.
Restrictions Apply
372 BIOCHIMICA ET BIOPHYSICA ACTA, 1974 - 1977.
Restrictions Apply
373 BIOINORGANIC CHEMISTRY, 1969 - 1978.
Restrictions Apply
374 General, 1973.
Restrictions Apply
375 General, 1974 - 1975.
Restrictions Apply
376 General, 1976.
Restrictions Apply
377 General, 1977.
Restrictions Apply
378 General, 1978.
Restrictions Apply
381 General, 1979. January - April.
Restrictions Apply
382 General, 1979. May-December.
Restrictions Apply
383 General, 1980.
Restrictions Apply
384 General, 1981.
Restrictions Apply
385 JOURNAL OF MOLECULAR EVOLUTION, 1969 - 1978.
Restrictions Apply
386 JOURNAL OF MOLECULAR EVOLUTION, 1979.
Restrictions Apply
387 JOURNAL OF MOLECULAR EVOLUTION, 1980 - 1981.
Restrictions Apply
388 JOURNAL OF THEORETICAL BIOLOGY, 1973 - 1974.
Restrictions Apply
389 JOURNAL OF THEORETICAL BIOLOGY, 1975.
Restrictions Apply
3810 JOURNAL OF THEORETICAL BIOLOGY, 1976 - 1977.
Restrictions Apply
3811 JOURNAL OF THEORETICAL BIOLOGY, 1985 - 1987.
Restrictions Apply
391 JOURNAL OF THEORETICAL BIOLOGY, 1988.
Restrictions Apply
392 JOURNAL OF THEORETICAL BIOLOGY, 1989.
Restrictions Apply
393 JOURNAL OF THEORETICAL BIOLOGY, 1990.
Restrictions Apply
394 JOURNAL OF THEORETICAL BIOLOGY, 1991.
Restrictions Apply
395 National Science Foundation, 1973 - 1977.
Restrictions Apply
396 National Science Foundation, 1978.
Restrictions Apply
397 National Science Foundation, 1979.
Restrictions Apply
398 National Science Foundation, 1980.
Restrictions Apply



Finding aid generated: 2005-10-31