Restrictions

Laboratory notebooks and research files containing medical records are restricted until the year 2067. Files containing administrative files are restricted until 2084.

Abstract

Papers of Robert N. Hamburger, UCSD professor of pediatrics and researcher in allergy and immunology. Hamburger investigated the relationship between peptides and immunoglobulin E (IgE) antibodies and synthesized human IgE pentapeptide (HEPP), a substance shown to inhibit allergic response. Included in the collection are laboratory notebooks (1960-1984), extensive research files on Hamburger's allergy studies, correspondence, and Food and Drug Administration documents related to animal and human testing. Also included are business files related to Allergy Peptide Company, Inc. (APCo, Inc.); Cytotech, Inc.; Immunetech, Inc.; Immunetech Research Partners; and Syntex Corporation, biotechnology firms that attempted to develop HEPP as a commercial product. The collection also contains biographical materials, writings, lectures, correspondence, and materials related to Hamburger's involvement in professional organizations. The later accessions include UCSD administrative documents including committtee materials and documents related to the history of the School of Medicine.

Biography

Robert N. Hamburger was born in New York on January 26, 1923. He received his B.A. in zoology and chemistry in 1947 from the University of North Carolina and attended Yale University School of Medicine (1947-1951), where he conducted research on LE cells. Hamburger carried out his medical residency at Strong Memorial Hospital in Rochester, N.Y., and Yale University School of Medicine. Between 1960 and 1963, as a Special Fellow of the National Institutes of Health, he studied molecular genetics and immunology in the UCSD Department of Biology. In 1964, he was appointed associate professor of pediatrics at the UCSD School of Medicine and served as its Assistant Dean for Faculty and Curriculum Affairs (1964-1969). In 1967, during a six-month semi-sabbatical at Guy's Hospital Medical School, London, he studied the development of immunologic systems in the human newborn. Hamburger was appointed head of the Pediatric Immunology and Allergy Division of the UCSD School of Medicine in 1969.

Hamburger's laboratory research with immunoglobin E (IgE) during the early 1970s led to the synthesis of a peptide, human immunoglobin E pentapeptide (HEPP), that inhibited allergic reaction in a limited "in vivo" test. He published his findings in an article in Science (August 1, 1975) entitled "Peptide Inhibition of the Prausnitz-Kustner Reaction." The University of California obtained two patents for HEPP: "Polypeptide Agents for Blocking the Human Allergic Response" (1976) for the peptide, and "Method for Blocking Allergic Response" (1979) for a method of delivery. In March of 1977, amid optimism over HEPP's potential as a cure for allergy sufferers, Syntex Corporation, a Palo Alto biotechnology firm, bought the rights and a two year research option to develop HEPP as a product. Syntex dropped the project after a year and a half when no suitable test animal could be found to replicate human response. In 1978, Hamburger entered into an option agreement with the University of California and formed APCo, Inc. (Allergy Peptide Company, Inc.), with the purpose of advancing his research through the first stages of FDA approval.

In 1981, Hamburger and UCSD doctors Richard O'Connor and Gary Hahn formed Immunetech Research Partners to finance further stages of the peptide research. This partnership purchased the assets of APCo, Inc., including all of its research materials and, signed a research and development agreement with Immunetech, Inc., a separate company formed with venture capitalist Ray McKewon of the Enterprise Management Company. Immunetech, Inc., then purchased both UC-owned patents and attempted to develop HEPP as a product but eventually dropped the project. Hamburger was the first executive vice president of Immunetech, Inc., and was involved in research and development until 1985.

Robert Hamburger retired from UCSD in 1990 as emeritus professor and continues to conduct private research and development activities.

Scope and Content of Collection

The Robert Hamburger Papers document allergy and immunology research in Hamburger's laboratory at UCSD and the development of human IgE pentapeptide (HEPP). The collection contains laboratory notebooks (1960-1984), research materials on Hamburger's peptide studies, FDA documents, patent and grant material, and writings by Hamburger and others. Also included are business records and agreements with: APCo, Inc.; Cytotech, Inc.; Immunetech, Inc.; Immunetech Research Partners; Enterprise Management Company; and Syntex Corporation, biotechnology firms associated with the development of HEPP. Other materials include UCSD administrative files and development documents for the School of Medicine.

SERIES 1: BIOGRAPHICAL MATERIAL

The BIOGRAPHICAL MATERIAL series contains directory entries, Hamburger's curriculum vitae, news clippings, photographs, correspondence from his sabbatical leave at Guys Hospital, London, a journal of medical notes from Strong Memorial Hospital, and material from Yale University's 25th Class Reunion Symposium .

SERIES 2: RESEARCH MATERIAL

The RESEARCH MATERIAL series constitutes the bulk of the collection and is arranged in four subseries: A) Laboratory Notebooks, B) Laboratory Subject Files, C) Patent Files, and D) Grant Files.

A) The Laboratory Notebooks subseries contains laboratory research data compiled at UCSD by Hamburger, his colleagues and graduate students from 1960-1984. The notebooks contain lupus studies, immune kill studies, immunoglobulin E (IgE) and diphtheria assays, lymphocyte transformation studies, and peptide research data. The notebooks are arranged chronologically. The majority of notebooks in this series contain medical records and are restricted.

B) The Laboratory Subject Files (1962-1989) subseries contains laboratory notes, general laboratory correspondence, FDA correspondence, and FDA documents. Research contained in this subseries was conducted primarily at UCSD; however, some clinical trials where carried out at other institutions and, in some cases, sponsored by private firms including APCo, Inc., Immunetech, Inc., and the Schering Corporation. The majority of data in this subseries consists of peptide studies and HEPP (human IgE pentapeptide) trials on animals and humans, including subcutaneous testing, toxicology tests, ophthalmic solution testing, and intranasal solution tests. Other studies include Albuterol research, diphtheria-tetanus tests and a twin study. The files are arranged chronologically.

C) The Patent Files subseries is arranged chronologically and contains patent-related correspondence (1974-1986), agreements between the University of California and APCo, Inc., and drafts of Hamburger's two patents entitled "Polypeptide Agents for Blocking the Human Allergic Response" (1976) and "Method for Blocking Allergic Response" (1979).

D) The Grant Files subseries contains documentation of research grants from the National Institutes of Health (1962-1979) and the University of California, San Diego (1965 and 1977). Also included is one unfunded grant proposal to the American Cancer Society (1969).

SERIES 3: WRITINGS BY HAMBURGER

This series, which includes a bibliography of Hamburger's writings, is arranged in three subseries: A) Abstracts and Reprints, B) Talks and Lectures and C) Book Reviews for Journals.

A) The Abstracts and Reprints subseries is arranged alphabetically by title and contains materials dated 1950-1986. Included are draft chapters 1-10 of an unpublished book entitled "Pediatric Immunology and Allergy" and writings on passive immune kill, immunoglobulin E (IgE) and other immunology and allergy-related topics.

B) The Talks and Lectures subseries is arranged alphabetically by title and contains materials dated 1965-1983. Presented at various meetings and classes, materials include manuscript drafts, typescripts, lists of slides, and some correspondence. Lecture topics include immunoglobulin E (IgE), human IgE pentapeptide (HEPP) and other research associated with allergy and immunology.

C) The Book Reviews for Journals subseries is arranged alphabetically by title of journal and contains book reviews by Hamburger for Annals of Allergy, Journal of Allergy and Clinical Immunology, Journal of Laboratory and Clinical Medicine, and Science. Materials in this series, which include correspondence, are dated 1977-1985. SERIES 4: WRITINGS OF OTHERS

This series is arranged alphabetically by author and includes writings by other authors that Hamburger annotated.

SERIES 5: BIOTECHNOLOGY DEVELOPMENT FIRMS

This series documents the participation of biotechnology and investment firms in developing HEPP as a commercial product and is arranged in six subseries: A) APCo. Inc. (Allergy Peptide Company, Inc.); B) Cytotech, Inc.; C) McKewon and Timmons Investment Bankers; D) Immunetech, Inc.; E) Immunetech Research Partners; and, F) Syntex Corporation.

A) The APCo, Inc. (Allergy Peptide Company, Inc.), subseries is arranged alphabetically and contains business documents and correspondence from its establishment in 1978 by Robert Hamburger through its dissolution in 1982. For APCo, Inc., sponsored research studies see Series 2. RESEARCH MATERIAL.

B) Cytotech, Inc., is arranged alphabetically and contains Hamburger's consulting and shareholder materials, including reports, business documents and correspondence dated 1981-1988.

C) McKewon and Timmons Investment Bankers is arranged alphabetically and contains correspondence and shareholder materials dated 1983-1987. Prior to McKewon and Timmons, Ray McKewon was affiliated with the Enterprise Mangement Company, which was involved in business agreements with Immunetech, Inc., and Immunetech Research Partners. Those materials are located in the following two subseries.

D) Immunetech, Inc., is arranged alphabetically and contains business agreements, correspondence, financial reports, meeting agendas, meeting minutes, and shareholder materials dated 1976-1992. Materials dated 1981 to 1985 reflect Hamburger's primary involvment with this company, including its establishment and initial business negotiations. For Immunetech, Inc., sponsored research studies see Series 2. RESEARCH MATERIAL.

E) Immunetech Research Partners is arranged alphabetically and contains business agreements and shareholder materials dated 1981-1982. Most of these materials document the first year of this partnership (1981) between Robert Hamburger, Richard O'Connor and Gary Hahn.

F) Syntex Corporation is arranged alphabetically and contains a consulting agreement with Hamburger, a license agreement with the University of California Regents and a press release regarding the company, all of which are dated 1976. For Syntex Corporation sponsored research studies see Series 2. RESEARCH MATERIAL.

SERIES 6: PROFESSIONAL ORGANIZATIONS

Arranged alphabetically, this series contains correspondence, committee rosters and meeting materials for professional organizations in which Hamburger participated. Among the organizations represented are: the American Academy of Allergy and Immunology; the American Academy of Pediatrics; the American College of Allergy and Immunology; the California Medical Association; the Nuffield Foundation; the San Diego County Medical Society; and, the Western Society for Pediatric Research.

SERIES 7: UCSD GENERAL CAMPUS

The UCSD GENERAL CAMPUS files are documents pertaining to subjects relating to the administration of the campus and how they relate to the School of Medicine. Subjects include building of the campus, development of academic programs, the activities of individual departments and institutes, and committees Hamburger participated in, at the campus and systemwide levels. The files are arranged alphabetically.

The series also includes Hamburger's files on the UCSD Chamber Music Series. The files, labeled "Quartet Series," detail Hamburger's involvement in beginning, planning, and supporting the series. Materials include correspondence, programs, notes, planning documents, tickets, and clippings for the series that has evolved into UCSD's ArtPower! Chamber Music Series.

SERIES 8: UCSD SCHOOL OF MEDICINE

The materials of the UCSD SCHOOL OF MEDICINE, arranged alphabetically, are administrative and developmental files documenting Hamburger's involvement with committees, curriculum, residency training, and the Basic Medical Sciences building advisement. Included are several folders pertaining to the history of the school of medicine with interviews, events, and planning.

SERIES 9: ORIGINS OF THE SCHOOL OF MEDICINE AT UCSD

Documents include the correspondence and typescripts for the UCSD School of Medicine memoir, Origins of the School of Medicine at UCSD , written by Robert Hamburger and the one day symposium (November 1, 1984) transcript drafts and correspondence. The personalized history document honored both the 25th Anniversary of the founding of UCSD and the 20th Anniversary of the School of Medicine. Participants of the symposium included Herbert York, Clark Kerr, Roger Revelle, John Galbraith, Robert Hamburger, and Joseph Stokes.

BIOGRAPHICAL MATERIAL

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1 1 Biographical materials published in various directories, 1965 - 1968.
1 2 Committee service lists, 1966 - 1968.
1 3 Curriculum vita, 1981.
1 4 News clippings, 1965 - 1985.
1 5 Photographs of Robert N. Hamburger, 1975.
1 6-7 Sabbatical correspondence, A-Z, 1967.
1 8 Strong Memorial Hospital journal of medical notes, 1952 - 1953.
1 9 Yale University 25th Reunion Class Symposium, 1976.

RESEARCH MATERIAL

Laboratory Notebooks

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2 1 1960 October 23 - September 28: Workbook.
2 2-3 1961-1963: Auto Ab and Lupus Studies.
2 4-6 1962: Hela H and R Study, raw data.
2 7 1963 January 28 - June 18: Hela H and R Immune Kill Study, raw data - Book II.
2 8 1963 August 26 - 1964 May 30: Passive Immune Kill - Book III.
3 1 1966 February 8 - December 14: Book VIII - Robert Hamburger and J. Douglass.
Restrictions Apply
3 2 1966 December 13 - 1967 November 7: UCSD School of Medicine - R. Hamburger and J. Douglass.
Restrictions Apply
3 3 1967 July 1 - December 15: Book I - Robert Hamburger.
Restrictions Apply
3 4 1968 December 19 - 1969 July 23: Antibody Binding Extracorporeal, Book I - Michael Bazaral.
3 5 1970 July 10 - 1972 June: Hemagglutination Assay/Thyroglobulin Immunoabsorbtion - Michael Slaughter.
Restrictions Apply
3 6 1970 August 27 - 1971 March 4: Immunoglobin Assays - M. Bazaral, R. Hamburger and H. A. Orgel.
Restrictions Apply
4 1 1970 December 2 - 1972: Twin Study ledger book.
Restrictions Apply
4 2 1971 January 10 - 1973 February 2: Book 6 - Michael Bazaral.
Restrictions Apply
4 3 1971 February 16 - October 21: Hospital Quantitative IgE Studies and Results - C. Ashcraft.
Restrictions Apply
4 4 1971 June 17 - August 23: IgE.
Restrictions Apply
4 5 1971 September 14 - 1972 May 4: IgE Assays I - Eva Lydick.
Restrictions Apply
4 6 1972 January 20 - June 19: Book 3 - Eva Lydick.
Restrictions Apply
4 7 1972 January 20 - 1977 May 31: Immunizations and Bleedings.
5 1 1972 February - 1973 May 30: H. Alice Orgel.
Restrictions Apply
5 2 1972 March 14: Navy Babies/IgE Levels of Newborns - Michael Lenoir and H. Alice Orgel.
Restrictions Apply
5 3 1972 May 10 - 1973 January 10: IgE Assays II - Eva Lydick.
Restrictions Apply
5 4 1972 October 19 - 1973 October 30: Diphtheria Assay I.
Restrictions Apply
5 5 1972 December 1 - 1973 March 31: Laboratory Notes - Robert Hamburger.
Restrictions Apply
5 6 1973 January 17 - 1974 March 29: IgE Assays III - Eva Lydick.
Restrictions Apply
5 7 1973 June 25 - 1974 March 8: Book 7 - Eva Lydick.
Restrictions Apply
6 1 1973 October 31 - 1976 June 10: Diphtheria Assay II - Book 2.
Restrictions Apply
6 2 1974 January 18 - 1975 June 24: Mad Scientist - Harvey Gorrin.
Restrictions Apply
6 3 1974 March 13 - October 15: IgE Assays IV - Robert Hamburger.
Restrictions Apply
6 4 1974 June 4 - 1975 August 14: Mason I - Donna Mason.
Restrictions Apply
6 5 1974 July 10 - 1976 May 18: Precipitins to Milk and Precipitins to Aspergillus - Lab Book 1.
Restrictions Apply
6 6 1974 October 21 - 1975 January 7: IgE Assay V.
6 7 1974 December 19 - 1975 September 2: IgE Double Ab Assay.
Restrictions Apply
7 1 1975 January 4 - 1983 January: Immunoglobulins.
Restrictions Apply
7 2 1975 October 7 - 1976 July 17: BSB 4033 Book II - Robert Wilcsek.
Restrictions Apply
7 3 1976 June 1 - 1979 September 21: Milk Precipitins and Hypersensitivity Pneumonitis - Lab Book 2.
Restrictions Apply
7 4 1976 August 26 - 1982 July 29: Pediatric Immunology and Allergy Division - D. Mason, D. Melvin and M. Wiley.
Restrictions Apply
7 5 1976 September 29 - 1978 January 4: IgE Double Ab Assay.
Restrictions Apply
7 6 1976 November 17 - 1977 July 14: Histamine/IgE Assays.
Restrictions Apply
8 1 1977 January 24 - August 23: Lymphocyte Transformation Studies I - Sylvia Johnson.
Restrictions Apply
8 2 1977 June 20 - August 22: Lymphocyte Transformation and Rosettes Patients I - Sylvia Johnson.
Restrictions Apply
8 3 1977 June 20 - August 22: Lymphocyte Transformation and Rosettes Patients II - Sylvia Johnson.
Restrictions Apply
8 4 1978 July 19 - 1979 March 21: Basophil Degranulation Inhibition by Pentapeptide - Bob Ziering.
Restrictions Apply
8 5 1979 October 25 - 1980 April 30: Etiologic Role of Allergic Rhinitis in Serous Otitis Media - D. Cook, H. Ort.
Restrictions Apply
8 6 1980 July 28 - 1985 August 2: Lymphocyte Transformation - Book IV.
Restrictions Apply
8 7 1981 February 10 - 1982 August 10: Diphtheria Assay - Book IV.
Restrictions Apply
9 1 1981 February 12 - 1983 March 16: Pediatric Immunology and Allergy Division - Hector Heredia.
Restrictions Apply
9 2 1981 April 22 - November 23: Pediatric Immunology and Allergy Division/Kaiser study - Quants, IgA, M and G.
Restrictions Apply
9 3 1981 September 12 - December 14: Peptide Research - John Bastian.
Restrictions Apply
9 4 1981 October 13 - 1982 March 23: ISP - Diana Hu.
Restrictions Apply
9 5 1982 July 12 - 1983 February 7: Diphtheria E.I.A.
Restrictions Apply
9 6 1982 December 21 - 1984 September 10: Serum Free Media, Human Dagmara Tubelis.
Restrictions Apply
9 7 1983 March 7 - May 4: Pediatric Immunology and Allergy Division, lab data - Hector Heredia.
10 1 1983 March 11 - June 22: Peptide Studies - Maryetta Hornbeck.
Restrictions Apply
10 2 1983 November 7 - 1984 May 29: AIDS Study.
Restrictions Apply
10 3 1984 January 5 - December 22: RAST Worksheets.
Restrictions Apply

Laboratory Subject Files

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11 1 1962: Tissue culture summary data.
11 2-5 1964 - 1967: Correspondence.
11 6 1967: Lab result photos, urea/glycine gel.
11 7 1968: Correspondence.
11 8 1970: IgE mother-baby study.
11 9 1970-1972: Twin study.
Restrictions Apply
11 10 1974: Correspondence.
11 11 1974: Disophrol and it's components in seasonal allergic rhinitis study.
11 12-14 1974-1978: Albuterol studies - Schering Corporation.
11 15 1974-1979: Allergy in infants study.
Restrictions Apply
11 16 1975: Correspondence - FDA.
11 17 1975: Correspondence - General laboratory.
11 18 1975: In vitro pentapeptide tests, 1-7.
11 19 1975: Peptide displacement experiment.
11 20 1975: Peptide inhibition of allergy study.
11 21 1975: Peptide stability study, electrophoresis strip photos - Peninsula Laboratories, Inc.
11 22 1975-1977: Peptide studies - Syntex Corporation.
11 23 1976: Correspondence - FDA.
11 24 1976: Correspondence - General laboratory.
11 25 1976: IgE low level assay.
11 26 1976: Notice of claimed investigational exemption for a new drug - Pentapeptide D-S-D-P-R.
11 27 1976: Statement of investigator - Pentapeptide D-S-D-P-R.
12 1 1976: Thymosin in primary cellular immunodeficiencies protocol.
12 2 1976: Vaceril studies - Schering Corporation.
12 3 1976-1983: HEPP clinical studies summary, part I.
12 4 1976-1983: HEPP clinical studies summary, part II.
12 5 1977: Correspondence - FDA.
12 6 1977: Correspondence - General laboratory.
12 7 1978: Correspondence - FDA.
12 8 1978: FDA inspection.
12 9 1978: Peptides quality control records - Peninsula Laboratories, Inc.
12 10 1978-1979: Cyclic amp/gmp notes.
12 11 1978-1979: Passive immunity notes.
12 12 1978-1980: IgE low level studies.
12 13 1978-1980: Skin tests/radio allergosorbent test (RAST) results.
Restrictions Apply
12 14 1978-1983: Human IgE pentapeptide toxicology summary.
12 15 1979: Correspondence - FDA.
12 16 1979: Correspondence - General laboratory.
12 17 1979: HEPP inhibition of allergy study - APCo, Inc.
12 18 1979: IgE PRIST studies.
12 19 1979: Lab notes.
12 20 1979: Notice of claimed investigational exemption for a new drug - Pentapeptide D-S-D-P-R.
12 21 1979-1980: HEPP studies.
Restrictions Apply
12 22 1979-1984: HEPP clinical study summaries.
12 23 1980: Amino acid electrophoresis data.
13 1 1980: Correspondence - FDA.
13 2 1980: Correspondence - General laboratory.
13 3 1980: FDA inspection.
13 4 1980: Guidelines for the evaluation of endogenous peptides and their analogs.
13 5 1980: IgE/radio allergosorbent test (RAST) - Kaiser study.
Restrictions Apply
13 6 1980: Kallstad comparison data.
13 7 1980: Milestones document.
13 8 1980-1981: Enzyme immunoassay for immunoglobulin E study - CalBiochem.
13 9 1980-1981: Immunoradiometric assay for IgE - Hybritech, Inc.
13 10 1981: Correspondence - FDA.
13 11 1981: Correspondence - General laboratory.
13 12 1981: IgE research results - Hybritech, Inc.
Restrictions Apply
13 13 1981: Peptide nomenclature.
13 14 1981: Research results.
Restrictions Apply
13 15 1981-1982: Efficacy and safety comparison study of choledyl and theodur tablets - Warner Lambert/Parke Davis.
13 16 1981-1982: HEPP research results - UCLA Statistical/Biomathematical Consulting Center.
Restrictions Apply
13 17-18 1981-1983: HEPP therapeutic trial (25-day, 38 patient) double-blind, randomly selected, placebo-controlled.
13 19 1981-1983: Intranasal toxicity test in rabbits via nasal spray - Immunetech, Inc.
13 20 1982: Amino acid electrophoresis data.
13 21 1982: Correspondence - FDA.
14 1 1982: Correspondence - FDA.
14 2 1982: Correspondence - General laboratory.
14 3 1982: Efficacy of HEPP protein in the treatment of allergy.
14 4 1982: FDA inspection.
14 5 1982: HEPP acute intravenous toxicity study in mice.
14 6-7 1982: HEPP trial (14-day, 12 patient) double-blind, dose response, placebo-controlled.
Restrictions Apply
14 8-11 1982-1984: HEPP phase II, double-blind, randomized, placebo-controlled.
14 12 1982-1984: IgA and IgE research data.
14 13 1983: Clr = ClEs function.
14 14 1983: Correspondence - FDA.
14 15 1983: Correspondence - General laboratory.
15 1 1983: Diphtheria-tetanus test results.
Restrictions Apply
15 2 1983: HEPP subacute subcutaneous toxicity study in rats.
15 3 1983: IgE egg research data.
15 4 1983: SAI inspection of toxicological testing facility.
15 5 1983-1984: HEPP intranasal administration, double-blind study.
15 6-7 1983-1984: HEPP phase II study results and phase III clinical protocol - Immunetech, Inc.
15 8-9 1983-1984: HEPP phase III, subcutaneous, double-blind, randomized, placebo-controlled.
15 10-11 1983-1986: HEPP three-year plan, volumes I & II.
16 1 1984: Correspondence - FDA.
16 2 1984: Correspondence - General laboratory.
16 3 1984: HEPP metabolism studies.
16 4 1984: HEPP rabbit teratology - Science Applications, Inc.
16 5 1984: HEPP rat subchronic toxicology - Science Applications, Inc.
16 6 1984: HEPP safety and efficacy in patients with perennial allergic rhinitis.
16 7 1984: HEPP USAN listing request.
16 8 1984: Milk-specific IgA E.I.A.
16 9 1984: Notice of claimed investigational exemption for a new drug - Pentapeptide D-S-D-P-R, Immunetech, Inc.
16 10 1984-1986: HEPP ophthalmic clinical study - Immunetech, Inc.
16 11 1985: Correspondence - General laboratory.
16 12 1985: Diphtheria-tetanus test results.
Restrictions Apply
16 13 1985: HEPP double-blind study of the effect of 3 weeks of treatment on the nasal provocation test - Merck.
16 14 1985: HEPP ophthalmic solution.
Includes notice of claimed investigational exemption, animal toxicology results and ophthalmic solution clinical protocol - Immunetech, Inc.
16 15 1985: HEPP ophthalmic solution phase II clinical results - Immunetech, Inc.
16 16 1985: HEPP summary of data on the efficacy and tolerance.
16 17 1985: Statement of investigator - Pentapeptide D-S-D-P-R.
16 18 1986: Clinical advantages of HEPP over conventional antiallergy drugs - Draft report.
16 19 1986: Correspondence - General laboratory.
16 20 1986: Diphtheria-tetanus test results.
Restrictions Apply
16 21 1986: HEPP bioavailability study.
16 22 1986: HEPP for injection study.
16 23 1986: HEPP intranasal phase III study.
16 24 1986: HEPP ophthalmic solution dose range clinical trial summary.
16 25 1986: HEPP ophthalmic solution test results.
Restrictions Apply
17 1 1989: Nasal NDA summary, clinical section - Immunetech, Inc.
17 2 1989: Pentyde nasal solution three week safety and efficacy study - Immunetech, Inc.
17 3 Undated: Mitogen stim. indexes.
Restrictions Apply
17 4 Undated: Unidentified laboratory notes.

Patent Files

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17 5 1963: Agreement with the University of California.
17 6 1974-1975: Correspondence.
17 7 1976: Correspondence.
17 8 1976: Polypeptide Agents for Blocking the Human Allergic Response - Patent.
17 9 1977: Application amendment.
17 10-12 1977-1979: Correspondence.
17 13 1979: Method for Blocking Allergic Response - Patent.
17 14 1979: Option agreement.
Agreement for APCo's commercial development of Robert Hamburger's UC-owned patent entitled: Polypeptide Agents for Blocking the Human Allergic Response.
17 15 1980-1981: Correspondence.
17 16 1982: Agreement with the University of California.
17 17 1982: Correspondence.
17 18 1983-1986: Correspondence.

Grant Files

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17 19 1962-1967: Genetics course - National Institutes of Health.
17 20 1964: Research grant - National Institutes of Health.
17 21 1964-1971: Immune Kill and Cells in Tissue Culture - National Institutes of Health.
18 1 1964-1971: Immune Kill and Cells in Tissue Culture - National Institutes of Health.
18 2 1965: Research grant - University of California, San Diego.
18 3 1969: Antigenic Enhancement by Foreign Haptens - American Cancer Society (not funded).
18 4 1971: Genetics of Immunoglobulin E - National Institutes of Health.
18 5 1976-1977: Development and Genetics of IgE and Allergy - National Institutes of Health.
18 6 1977: Atopy and IgE Synthesis - National Institutes of Health.
18 7 1977: Safety and Toxicity of Synthetic IgE - University of California, San Diego.
18 8 1979: Biomedical Research Support Grant - National Institutes of Health.
18 9 Undated: Development of Immunoglobulin E - National Institutes of Health.

WRITINGS BY ROBERT HAMBURGER

Abstracts and Reprints

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18 10 Robert Hamburger's bibliography, 1950 - 1978.
18 11 All About Allergy Shots - Abstract, 1976.
18 12 Allergy and the Immune System - Reprint, 1976.
18 13 Anaphylaxis-like Reactions to Corticosteroid Therapy - Photocopy of original article, 1974.
18 14 Antigenic Determinants on the Chloramphenicol Molecule - Abstract, undated.
18 15 Antigenic Specifications Acquired From the Growth Medium by Cells in Tissue Culture - Reprint, 1963.
18 16 Atmospheric Pollen and Spore Sampling in San Diego, California - Reprint, 1976.
18 17-18 Chloramphenicol-Specific Antibody - Abstract & reprint, 1966.
18 19 Clonal Growth of Primary Human Cell Cultures - Reprint, 1964.
18 20 Conservation of Active Sites in Molecules with Immunoglobulin Fold Domain Structure - Reprint. (Chapter 16 of Immunologic Analysis), undated.
18 21 Current Status of the Clinical and Immunologic Consequences of a Prototype Allergic Disease Prevention Program - Typescript, 1983.
18 22 Development and Inheritance of IgE and Allergy - Reprint, 1974.
18 23 Development and Inheritance of IgE Mediated Hypersensitivity - Typescript, 1978.
18 24 Development of Atopic Allergy in Children - Reprint, 1980.
18 25 Development of Gamma Globulins in the Human Newborn - Abstract, 1968.
18 26-27 Development of IgE and Allergy in Infancy - Typescript & reprint, 1974.
18 28 Diagnosis and Prophylaxis of Atopic Allergic Diseases in the First Three Years of Life - Reprint, 1979.
18 29 Evolutionary Relationship of Thymopoietin to Immunoglobulins and Cellular Recognition Molecules - Reprint, 1981.
18 30 Genetics of IgE and Allergy: Serum IgE Levels in Twins - Reprint, 1974.
18 31 IgE and Allergy - Reprint, 1976.
18 32 IgE Levels in Normal Infants and Mothers and an Inheritance Hypothesis - Reprint, 1971.
18 33 Immunoglobulin E in Leprosy - Abstract, undated.
18 34 Induction of the Lupus Erythematosus ("L.E.") Cell In Vitro in Peripheral Blood - Reprint, 1950.
18 35 Inhibition by IgE Pentapeptide of IgE Rosette Formation by Human Basophils - Abstract, 1982.
18 36 Inhibition of IgE Binding to Tissue Culture Cells and Leucocytes by Pentapeptide - Photocopy of original article, 1979.
18 37 Metabolism of IgE in Transfused Infants - Abstract, 1974.
18 38 New Experimental Approaches to the Therapy of Atopic Diseases - Galley proof & reprint, 1983.
18 40 New Means for Serum IgE Levels Result from Changes in Measurement Methodology - Abstract, 1979.
18 41 Newer Bronchodilators - Abstract, undated.
18 42 Niveles de Immunoglobulina E, Herencia a la Alergia e Inmunidad a las Helmintos - Photocopy of original article, 1973.
18 43 Of Many Things... And the Immune System - Reprint, 1978.
18 44 Office Diagnosis of Immunodeficiency Disease - Typescript, undated.
18 45-46 Passive Immune Kill and Pseudo-Autoimmune Disease: Proposed Model for Chloramphenicol Induced Aplastic Anemia - Correspondence, 1967-1968.
18 47-49 Passive Immune Kill of Cells in Tissue Culture - Correspondence, reprint & typescript, 1965.
Pediatric Immunology and Allergy.
18 50 Chapter 1: Introduction - Draft, undated.
18 51 Chapter 2: Human Fetal Immune System - Draft, undated.
18 52 Chapter 3: Development of Antigen Responses in the Fetus - Draft, undated.
19 1 Chapter 3: Reference articles.
19 2 Chapter 5: Development in the First Year of Life - Draft, undated.
19 3 Chapter 5: Reference articles.
19 4 Chapter 6: Strategy of Immunizations - Draft, undated.
19 5 Chapter 6: Reference articles.
19 6 Chapter 7: Some Genetics of the Immune System - Draft, undated.
19 7 Chapter 7: Reference articles.
19 8 Chapter 8: Draft, undated.
19 9 Chapter 8: Reference articles.
19 10 Chapter 9: Pages 7-9 only - Draft, undated.
19 11 Chapter 10: Laboratory Techniques - Draft, undated.
19 12 Correspondence, 1979.
19 13 Peptide Inhibition of the Prausnitz-Kustner Reaction - Reprint, 1975.
19 14 Prophylaxis of Allergy - Abstract, 1976.
19 15 Prophylaxis of Allergy in Infants Debate - Abstract, undated.
19 16-17 Radio Allergosorbent Test (RAST) and Skin Tests in Low IgE Individuals - Abstract & research notes for writing, 1979 - 1980 & undated.
19 18 Recent Studies with Human IgE Pentapeptide (HEPP) - Reprint, 1981.
19 19 Regulation and Measurement of IgE in Atopy - Typescript, undated.
19 20-22 Results of a Double-Blind Randomly Selected Placebo-Controlled Therapeutic Trial of Human IgE Pentapeptide - Abstract, undated.
19 23 Safety and Efficacy of Human IgE Pentapeptide - Abstract, 1984.
19 24 Separation of Electophoretic Bands from a Bence-Jones Protein - Abstract, 1968.
19 25 Some New Studies With Human IgE Pentapeptide (HEPP) - Abstract, undated.
19 26 Standardization and Stability of Immunoglobulin E (IgE) - Reprint, 1972.
19 27 Statement from UCSD to the California Senate Fact Finding Committee of Public Health and Safety - Typescript, 1966.
19 28 Studies of Human IgE Pentapeptide: HEPP - Reprint, 1980.
19 29-30 Transfused Immunoglobulin E in Newborns, Letter to the Editor - Photocopy of original article & typescript, 1982.
19 31 Unidentifiable notes, figures and tables used in miscellaneous writings, undated.
19 32 Untitled, undated writing.
19 33 Use of the Laboratory in the Diagnosis of Allergic Disease - Photocopy of original article, 1986.
19 34 Value of PRIST, RAST and Skin Tests in Selected Individuals - Abstract, undated.

Talks and Lectures

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19 35 List of talks and lectures by Robert Hamburger, 1965 - 1968.
19 36 Allergic Tissue Damage and Foreign Anitgens - Typescript, 1969.
Presented at the 4th Nuffield Conference on Rheuatism, Oxfordshire, England.
19 37 Allergy, Immunology and the Inheritance of IgE Levels - Typescript, 1971.
Presented at a West Coast Allergy Society meeting.
19 38 Allergy, Pathology Lecture - Handwritten introduction and list of slides for lecture, 1982.
19 39 Allergy Physician's Assistant (APA) Training Program - Abstract, 1975.
Presented at an American Academy of Allergy meeting.
19 40 Allergy Testing for the Primary Care Physician - Typescript outline, 1982.
Presented at the 26th Annual Symposium of the San Diego Academy of Family Physicians.
19 41 Atopic Asthma - List of slides, 1980.
Presented at a meeting in Medellin, Columbia.
19 42 Atopy, Hypersensitivity or Allergy - Handwritten draft, 1976.
Presented to Core Medical Education students.
Biologic Basis For a New Therapeutic Approach to Allergic Disease.
19 43 Abstract, 1975.
Presented at an American Academy of Allergy meeting and the Second Charles Blackley Symposium.
19 44 List of slides, undated.
Presented at the Second Charles Blackley Symposium.
19 45 Biology of IgE - List of slides, 1977.
Presented at Pomona College, California.
19 46 Blockade of Mast Cell Receptors for the Treatment of Human Allergies - Handwritten draft, 1976.
Presented at a Canadian Society of Allergy and Clinical Immunology meeting.
19 47 Clinical Manifestations of Atopy - List of slides, 1977.
Presented to a Pathology class.
19 48 Development and Genetics of IgE and Allergy - Typescript, 1976.
Presented at a joint meeting of the Northern California Section of the American Association of Clinical Chemists and the California Association of Bioanalysts.
19 49 Development and Inheritance of IgE Mediated Hypersensitivity - List of slides, 1978.
Presented at USC's Practical Allergy and Immunology Conference.
19 50 Development of IgE and Allergy - Handwritten outline, 1975.
Presented to biology students at Mar Vista High School, San Diego.
Development of IgE and Allergy During the First Year of Life: Preliminary Data.
19 51 Abstract, 1974.
Presented at the 30th Annual American Academy of Allergy Meeting.
19 52 Correspondence, 1973 - 1974.
19 53 Research notes for lecture, 1974.
19 54 Development of IgE in Infancy and Childhood - Handwritten draft, 1975.
Presented at a West Coast Allergy Society meeting.
19 55 Development of the IgE Allergy System and it's Effect on Subsequent Atopic Allergy - Typescript and slide list.
Undated.
19 56 Developmental Immunology and Allergy in the First Two Years of Life - Handwritten draft, 1975.
Presented at a March of Dimes sponsored event at Sunrise Hospital, Las Vegas, Nevada.
19 57 Diagnostic Update in Allergy - Handwritten outline and list of slides, 1977.
Presented at Paradise Valley Hospital, San Diego for the Core Medical Education Program.
19 58 Diagnostic Value and Problems of Skin Tests, PRIST and RAST and Food Allergy - Tables used in lecture, 1980.
Presented at a meeting in Monterrey, Mexico.
19 59 Dose Response to Human IgE Pentapeptide (HEPP) - Abstract, 1983.
Presented at the 39th Annual Congress of the American College of Allergists, New Orleans, Louisiana.
20 1 Effect of Oral Albuterol on Plasma Cyclic Adenosine Monophosphate - Abstract, 1975.
Presented at an American Academy of Allergy meeting.
20 2 Experience with Carnation Hypoallergenic Formula - Typescript, 1988.
Presented at the Food Allergy Symposium, New York.
20 3 Genetics and Allergy - Typescript, 1982.
Presented at the Southwest Allergy Symposium.
20 4 IgE and Allergy - List of slides, 1974.
Presented at the U.S. Naval Hospital, Pediatrics Department, San Diego.
20 5 IgE and HEPP on the Wil-2 WT Cell (lecture 1) and Mechanism and Inheritance of Allergy (lecture 2), 1978.
Contains list of slides for both lectures. Presented at a meeting in Birmingham and to Core Medical Education students.
20 6 IgE, Biology and Clinical Activity - List of slides, 1974.
Presented at the U.S. Naval Hospital, Dermatology Department, San Diego.
20 7 IgE Blocking Peptide - Handwritten draft, 1975.
Presented at the San Diego Pulmonary Society Conference.
20 8 IgE in Allergy - Handwritten draft and list of slides, 1973.
20 9 IgE in Food Allergy - Typescript and photocopies of slides, undated.
20 10 IgE, Peptides and Allergy - Handwritten draft, 1975.
Presented at Grand Rounds, University Hospital, San Diego.
20 11 Immune Response to Chloramphenicol - Typescripts in English and Spanish, undated.
20 12 Immunization - Handwritten outline, 1966.
Presented at a Peace Corp meeting.
20 13 Immunodeficiency and Allergic States - Handwritten outline, 1980.
Presented at a meeting in Acapulco.
20 14 Immunologic Deficiency Disease - Handwritten outline and list of slides, 1975.
Presented at Doctor's Hospital, San Diego.
20 15 Immunology of Breast Milk and Phophylaxis of Allergy - Handwritten draft, 1979.
Presented at the Pediatric Grand Rounds, University Hospital, San Diego.
20 16 Immunotherapy - List of slides, undated.
20 17 Improved Screening Method for Anti-Chloramphenicol Antibodies - Abstract, 1970.
Presented at the 17th Annual Western Society for Pediatric Research meeting, Carmel, California.
20 18 Indications for Hyposensitization, Desensitization, Injection Therapy, and Immunotherapy - Handwritten outline, 1974.
Presented at the U.S. Naval Hospital, Pediatrics Department, San Diego.
20 19 International Meeting of Asthmology lecture - Typescript in English and Spanish, 1974.
Presented at the Interasma Conference, Havana, Cuba.
20 20 Is it Immune Deficiency or Just a Bad Winter? Typescript outline, 1982.
20 21 Joseph Weiner, M.D. Memorial Lecture - Handwritten draft introduction, 1983.
Presented at St. Raphael Hospital, Milford, Connecticut.
20 22 Journal Club Lecture - Handwritten draft introduction, 1966.
Presented at Children's Hospital of Orange County, California.
20 23 Los Angeles Allergy Society Lecture - Handwritten draft introductions, 1 - 3, 1975.
20 24 Management of Asthma - Handwritten draft, 1978.
Presented as an American Academy of Pediatrics Core Medical Education Course, University Hospital, San Diego.
20 25 More About IgE Than You'd Care to Know - Handwritten draft and list of slides, 1975.
20 26 Once Around [the World] - Handwritten draft, 1978.
20 27 Paramedical Aspects of Medical Treatment of Chest Diseases - Typescript, 1978.
Presented at the Interasthma Congress.
20 28 Pediatric Allergy - List of slides, 1980.
20 29 Peptide Inhibition of Allergic Reaction - List of slides, 1976.
20 30 Prediction, Prevention and Treatment of Allergic Asthma - Handwritten draft, 1976.
Presented at John D. Spreckles Lodge, San Diego. Sponsored by the Lung Association of San Diego and Imperial Counties.
20 31 Preparation for General Pediatrics and Sub-Specialty Training - Typescript, undated.
Presented at the Congresos De Pediatria, Mexico.
20 32 Present and Future in Treatment of Allergic Diseases - List of slides, 1980.
Presented at a meeting in Medellin, Colombia.
20 33 Prophylaxis of Allergy in Infants Debate - Handwritten outline and list of slides, 1976.
Presented at an immunology conference.
20 34 Prophylaxis of Atopic Asthma in the First Two Years of Life - Typescript, 1978.
Presented at the IX Interasthma Congress, New Orleans, Louisiana.
Pseudo-Autoimmune Disease.
20 35 Correspondence, 1965 - 1966.
20 36 Typescript, 1965.
Presented at the XI International Congress of Pediatrics, Tokyo, Japan.
20 37 Radio Allergosorbent Test (RAST) - List of slides, 1981.
Presented at the Second Annual Course on Selected Topics in Immunology, School of Medicine, University of Guadalajara.
20 38 Serum Assays for Antigen Specific IgE Antibody - Handwritten introduction and list of slides, 1981.
Presented at an American College of Allergists meeting.
20 39 Sickle Cell Anemia - Handwritten outline, 1969.
Presented at a Charles Drew Foundation meeting.
20 40 T-Cell Modulation of IgE Production - Handwritten introduction and list of slides, 1980.
Presented at a West Coast Allergy Society meeting, Acapulco.
20 41 Treatments of the Future - Handwritten introduction and list of slides, 1977.
Presented at the VII Congreso Medico Estatal, Tijuana, Mexico.
20 42 UCSD Allergy in Infancy Study: An Interim Report - Typescript and list of slides, 1978.
Presented at a West Coast Allergy Society meeting.
20 43 Understanding Allergy - Handwritten draft, 1976.
Presented at the UCSD Medical Center Auxiliary Health Education Lecture Series.
20 44 Values and Problems with PRIST and RAST in Children - Abstract, 1979.
Presented at the American Academy of Pediatrics Annual Meeting.
20 45 What Can Our Friends the Animals Tell Us About IgE Mediated Disease in Humans? Handwritten draft, 1975.
Presented at a Journal Club meeting.
20 46 Where Are We and Where Are We Going in Allergy? Handwritten note cards, undated.
20 47-48 Untitled lectures - Handwritten drafts and typescripts, 1973 - 1981.

Book Reviews for Journals

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20 49 Annals of Allergy, 1977 - 1985.
20 50 Journal of Allergy and Clinical Immunology, 1979 - 1985.
20 51 Journal of Laboratory and Clinical Medicine, 1977.
20 52 Science, 1973.

WRITINGS OF OTHERS

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20 53 List of writings of others kept on Robert Hamburger's desk, undated.
20 54-55 Annotated by Robert Hamburger, A - H.
21 1-2 Annotated by Robert Hamburger, I - V.
21 3 Unidentified authors.

BIOTECHNOLOGY DEVELOPMENT FIRMS

APCo, Inc. (Allergy Peptide Company, Inc.)

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21 4 Business documents, 1978 - 1982.
21 5 Correspondence, 1981 - 1982.
21 6 Deed of gift to the UC Regents, 1982.
21 7 Income tax returns, 1981 - 1982.
21 8 Joint venture proposal from Immunoscience Corp., 1979.
21 9 Option agreement, 1979.

Cytotech, Inc.

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21 10 Amended and Restated Articles of Incorporation, 1987.
21 11 Brochure, 1983.
21 12 Correspondence, 1982 - 1988.
21 13 Human complement product list, 1985.
21 14 News clippings of Cytotech, Inc., 1984 - 1985.
21 15 News clippings of other companies, 1981.
21 16-17 Private Placement Memorandum, 1982 - 1984.
22 1 Product proposals, undated.
22 2-4 Report and financial statements, 1983 - 1988.
22 5 Resolution Amending Articles of Incorporation as to Series B Convertible Preferred Stock, undated.
22 6 Series B Convertible Preferred Stock Purchase Agreement, 1984.
22 7 Series B Convertible Preferred Stock Registration Rights Agreement, 1984.
22 8 Shareholder Consent Form, 1989.
22 9 Unidentified report, undated.

McKewon and Timmons Investment Bankers

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22 10 Correspondence, 1983 - 1987.
22 11 News clippings, 1984.
22 12 Private Placement Memorandum, 1983.
22 13 Quarterly reports, 1984 - 1986.

Immunetech, Inc.

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22 14 Agreement for Purchase and Sale of Assets between Robert Hamburger, APCo, Inc. and Immunetech, Inc., 1981.
22 15 Agreements between Herbert S. Lightstone and Immunetech, Inc., 1982 - 1984.
22 16 Balance sheet, 1984.
22 17 Brochures, undated.
22 18 Business plan, 1983.
22 19 Business plan summary, 1989 - 1992.
22 20 Certificate of Amendment of Articles of Incorporation, 1982.
22 21 Company logo photograph, 1981.
22 22 Confidential Disclosure Agreement, undated.
22 23-25 Corporate overview, 1982 - 1983.
Correspondence.
23 1 Accounts payable, 1988.
23 2 Administrative office, 1986 - 1988.
23 3 Bausch and Lomb, Inc., 1985.
23 4 Blair, James, 1985.
23 5 Brucker, Donald, 1982 - 1985.
23 6 Down, Lisa and Norman, 1983.
23 7 Dura Pharmaceuticals, 1990.
23 8 Hahn, Gary S, 1981 - 1985.
23 9 Himel, G, 1982.
23 10 Kornberg Associates, 1983.
23 11 Lightstone, Herbert S, 1983 - 1986.
23 12 Lyon and Lyon Law Offices, 1983.
23 13 McKewon, Ray, 1981 - 1986.
23 14 Merck, E., undated.
23 15 Nelson, Norman, 1982.
23 16 O'Connor, Richard, 1982.
23 17 Pallai, Peter, 1981.
23 18 Phillips and Phillips, Attorneys at Law, 1981 - 1982.
23 19 Plummer, James, 1985.
23 20 Ramseier, Gordon, 1988.
23 21-22 Rangus, Kathryn, 1983 - 1987.
23 23 Richieri, Steven P, 1989.
23 24 Schmidt, Todd W, 1986 - 1989.
23 25 Shareholder materials, 1984 - 1991.
23 26 UCSD Office of Contract and Grant Administration, 1982.
23 27 Yakatan, Gerald J, 1989.
23 28 Development and License Agreement between Bausch and Lomb, Inc. and Immunetech, Inc., 1985.
23 29 Employment agreement, undated.
23 30 Expenses and financing, 1981 - 1986.
24 1-2 Financial statements, 1981 - 1986.
24 3 Human Complement System Proposal, 1982.
24 4 Investigator brochure, 1988.
24 5 Loan and Equity Investment Agreement, 1986.
24 6 Meetings 1981: Board of Directors (first) meeting - Minutes.
24 7 Meetings 1981: Research meeting - Agenda.
24 8 Meetings 1982: Building planning meeting - Minutes.
24 9 Meetings 1982: Meeting agendas.
24 10-12 Meetings 1983-1985: Board of Directors meetings - Agendas and minutes.
24 13 Meetings 1985: FDA meeting - Agenda and minutes.
24 14 Meetings 1985: Research presentation schedules.
24 15 Meetings 1985: Scientific Advisory Board meetings - Agendas and minutes.
24 16 Meetings 1986: Board of Directors meetings - Agendas and minutes.
24 17 Meetings 1986: Scientific Advisory meetings - Agendas.
24 18 Meetings 1987: Scientific Advisory meeting - Agenda.
24 19 Meetings 1987-1990: Shareholder meetings - Announcements.
24 20 News clippings, 1976 - 1990.
24 21 Notes on business and research, 1982 - 1986.
24 22 Private Placement Memorandum, 1984.
25 1-2 Private Placement Memorandum, 1985 - 1986.
25 3 Product Agreement with Merck, 1986.
25 4 Promissary Notes, 1985.
25 5 Proposal for the Acquisition of ABC Pharmaceuticals by Immunetech Pharmaceuticals, 1989.
25 6 Proposal to Endow a Chair in the Pediatric Immunology and Allergy Division, UCSD School of Medicine, 1982.
25 7 Report and financial statements, 1982 - 1983.
25 8 Restated Articles of Incorporation, 1986 - 1989.
25 9 Retainer Agreement with Enterprise Management Company, 1981.
25 10 Securities and Exchange Commission Registration Statement, 1984.
25 11 Securities Purchase Agreement, 1986.
25 12-13 Stockholder documents, 1981 - 1991.
25 13 Stockholder documents, 1986 - 1991.
25 14 Technology Sharing Agreement between Immunetech, Inc. and Cytotech, Inc., 1982.
25 15 Unanimous Written Consent of Directors, 1986.
25 16 Weingart Protein Sequencer Laboratory results, 1983.

Immunetech Research Partners

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25 17 Agreement between Immunetech Research Partners and the Enterprise Management Company, 1981.
25 18 Comprehensive Option Agreement between Immunetech Research Partners and Immunetech, Inc., 1981.
25 19 Discussion of Management's Proposal for Immunetech Research Partners "Roll Up", 1983.
25 20 Escrow Instructions, 1981.
25 21 Fictitious Business Name Statement, 1981.
25 22 License Agreement, draft, 1981.
25 23 Partnership Agreements between R. Hamburger, R. O'Connor and G. Hahn to form Immunetech Research Partners, 1980 - 1981.
26 1 Private Placement Memorandum, June 1981.
26 2 Private Placement Memorandum, July 1981.
26 3 Proposed Concept for a New Business, 1980 - 1981.
26 4 Quarterly Progress Reports, 1982.
26 5 Research and Development Agreement between Immunetech Research Partners and Immunetech, Inc., 1981.
26 6 Retainer Agreement, 1981.
26 7 Special Report, 1982.
26 8 Technology License Agreement between Immunetech Research Partners and Immunetech, Inc., 1981.

Syntex Corporation

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26 9 Consulting Agreement between Syntex and Robert Hamburger, 1976.
26 10 License Agreement between Syntex and University of California Regents, 1976.
26 11 Press release, 1976.

PROFESSIONAL ORGANIZATIONS

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American Academy of Allergy.
26 12 Correspondence, 1976 - 1980.
26 13 In Vitro Tests Committee, research data, meeting agendas and minutes, 1976.
26 14 American Academy of Allergy and Immunology - Correspondence, rosters and meeting minutes, 1980 - 1990.
26 15 American Academy of Pediatrics - Correspondence, 1978 - 1980.
26 16 American Association for Clinical Immunology and Allergy - Correspondence, 1978 - 1981.
26 17 American College of Allergists - Correspondence, 1980 - 1986.
26 18 American College of Allergy and Immunology - Correspondence and committee list, 1988 - 1990.
26 19 American Pediatric Society - Correspondence, 1972 - 1982.
26 20 California Committee on Therapeutic Abortion - Correspondence, 1966 - 1969.
26 21 California Medical Association - Correspondence, 1982 - 1983.
26 22 California Society of Allergy and Clinical Immunology - Correspondence, 1972 - 1990.
26 23 Children's Hospital Education Committee - Correspondence, 1968.
26 24 Clinica de Salubridad de Campesinos - Correspondence, 1974 - 1981.
26 25 First Mexican-American Congress of Clinical Immunology and Allergy - Correspondence and meeting materials, 1981.
27 1 Interasma - Correspondence, 1978 - 1988.
27 2 Los Angeles Society of Allergy and Clinical Immunology - Correspondence, 1976.
27 3 North County Health Services - Correspondence, 1980 - 1982.
27 4 Nuffield Foundation 4th Nuffield Conference on Rheumatism - Correspondence, meeting and travel materials, 1969.
27 5 San Diego Allergy Sociey 1st Annual Seminar - Program of events, 1976.
27 6 San Diego County Medical Society - Correspondence, 1979 - 1980.
27 7 San Diego County Mental Health Association - Correspondence, 1958 - 1964.
27 8 San Diego Pulmonary Society Conference - Program of events, 1975.
27 9 Society for Pediatric Research - Correspondence, 1964 - 1969.
27 10 UCSD Ninth Annual Course, Immunology and the Clinical Practice of Allergy - Program of events, 1985.
27 11 Western Society for Pediatric Research - Correspondence, 1969 - 1983.

UCSD GENERAL CAMPUS

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28 1-8 Academic Senate. Special Committee on Medical Education, 1960-1965.
29 1 Academic Senate. Special Committee on Medical Education - Expanded - Correspondence, 1966-1967.
29 2 Atkinson, Richard, 1980-1990.
29 3-5 Budget Committee, 1964-1966.
29 6-7 Chancellor's Advisory Committee on Equal Opportunity in Employment at UCSD, 1964-1968.
29 8 Experimental High School Program Committee, 1969.
30 1-2 Planning for UCSD overall - UC overall, 1966-1968.
30 3 Project 73 Committee, 1965-1966.
Quartet Series (UCSD Chamber Music Series).
40 1-8 1975 - 1988.
41 1 1989 - 1991.
30 4 Second College - Planning committee, 1964-1966.
30 5 Stern, Herb. Inaugural talk.
30 6 Third College - Operation Opportunity - Upward Bound Project, Subcommittee on Special Scholarships, 1968-1969.
30 7 Third College Planning Committee, 1969.

UCSD SCHOOL OF MEDICINE

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30 8 25th UCSD Anniversary Oral History Project - School of Medicine - Interview with Robert Hamburger - Final draft with edits, 1984.
30 9 Ad Hoc Committee to consider methods for utlizing San Diego County Pound dogs and cats, 1966.
30 10 Advisor's Handbook, 1968-1971.
31 1 Animal Care Panel - San Diego Branch. American Association for Laboratory Animal Science, 1965-1967.
Animal Facilities.
31 2-3 Correspondence, 1965-1983.
31 4 General, 1966-1971.
31 5 Animal Resources, 1966-1980.
31 6 Basic Science Building, 1966.
31 7 Basic Science Building Committee, 1967-1968.
31 8 Bellagio Study and Conference Center - Correspondence, 1986.
31 9 Beneficial Occupancy Committee, 1968.
31 10 Building Advisory Committee for the South Campus, 1967.
30 11 Building Advisory Subcommittee for Clinical Science Building 1, 2, La Jolla Campus Hospital and County - University Hospital, 1966-1967.
32 1-2 Camp Elliott Advisory Committee, 1966-1970.
32 3 Camp Elliott Animal Farm, 1966-1968.
32 4 Clinical Science Building, 1967-1969.
32 5-7 Clinical Science Building Advisory Committee, 1965-1969.
32 8 Clinical Science Building Project Site Visit, January, 1968.
32 9 Clinical Science Building Subcommittee, 1966-1967.
33 1 Commencement exercises - Scripts, June, 5, 1994.
33 2-3 Committee on Educational Policy, 1966-1970.
33 4 Committee on Electives, 1967-1968.
33 5 Committee on Evaluation and Grading, 1968-1971.
33 6 Committtee on Investigations Involving Human Beings, 1966-1968.
33 7 Committee to Develop a Master Plan for the Biomedical Use of Camp Elliott, 1968-1969.
33 8 Community Medicine, 1968-1972.
33 9-10 Core Curriculum Committee, 1967-1969.
33 11 Correspondence - Includes letter from Richard Nixon, 1968-1994.
33 12 Council of Chairman (Formerly called General Executive Council), 1966-1968.
34 1 Council of Chairman (Formerly called General Executive Council), 1968-1972.
34 2 Dean's Office, 1967-1968.
34 3 Developmental Program Grants, 1968.
34 4 Early Admissions Subcommittee of the Admissions Committee, 1970.
34 5 Elliott Field Station Advisory Committee - Includes annual report, 1971-1972.
34 6 Enrollment Projections, 1965-1967.
Expert Groups on Elective Concentration Areas Committee, 1968-1969.
34 8 First Mexican-American Congress of Clinical Immunology and Allergy, November, 1981.
First Year Curriculum Committee.
34 9-11 Includes pamphlets on other Schools of Medicine, 1964-1966.
34 12 First Year Curriculum Committee - Correspondence, 1965-1966.
35 1 First Year Curriculum Committee - Correspondence, 1966-1967.
35 2-3 First Year Curriculum Committee - Minutes, 1966-1967.
35 4 Full Time Employee - UC and School of Medicine, 1966-1967.
35 5 General Space Allocations (Lab, Offices, etc.), 1966-1968.
35 6 Graduate Program Accreditation, 1982-1983.
35 7 Grants, Additions, and Inserts, 1968.
35 8 Improvements at University Hospital - Project Planning Guide. 1970-1971, January 31, 1969.
35 9 Interview of Robert Donald Tschirgi - Transcript, 1981.
35 10 Interview of Dean G. Burrow by Robert Hamburger - Transcript, April 17, 1989.
36 1 Janis, Irving L., 1973.
36 2 John M. and Sally B. Thornton Hospital - Groundbreaking Ceremony - Program, March 7, 1990.
36 3 Joint Research with David Marsh, 1974-1975.
36 4 Major Capital Improvements, 1967.
36 5 Mental Retardation Research and Training Committee, 1968.
36 6 Miscellaneous, 1964-1976.
36 7 Neuroimmune Physiology Program - Gift Fund, 1988.
36 8 Neurosciences Department, 1968-1969.
36 9 Obstetrics and Gynecology Department, 1968.
36 10 Office Space - Pediatric Office Space, Basic Science Building, La Jolla Campus, 1968-1969.
36 11 Pathology Department, 1968-1977.
36 12-13 Peace Corps Training Program, 1966-1967.
Pediatric Immunology and Allergy Division (PIAD).
36 14-15 1977-1987.
37 1 Miscellaneous, 1969-1988.
37 4-5 Residency Training Program, 1974-1988.
37 6 Pediatrics Department, 1977.
37 7 School of Medicine Planning, 1964-1969.
38 1 Planning Guides for School of Medicine, 1969-1983.
38 2 Proposal for New Departments in the School of Medicine.
38 3 Quantitation of Some of the Variables in Allergy - Grant Materials, 1978.
38 4 Recruitment and Admissions Committee, 1966-1970.
Restricted
38 5 Recruitment of Dr. Bonner, Dr. Zimm and Dr. Salk - Newsclippings.
38 6 Regional Medical Program Advisory Committee, 1966-1967.
38 7 Review and Updating of the Immunology and Clinical Practice of Allergy, San Diego - Brochures, 1977-1979.
38 8 Research Institutes at UCSD, 1966-1967.
38 9 Residency Training and Pediatric Research Projects: A Study, 1965.
38 10 Salk Surge, 1968.
38 11 Salk Temporary Buildings, 1966-1967.
38 12 San Diego County Public Health Planning, 1963.
38 13 Scale "C" Debate, 1966-1968.
38 14 Scripps Clinic and Research Foundation, 1967.
38 15 Stokes, Joseph III - Speech at Groundbreaking Ceremony for Basic Science Building, 1966.
38 16 Strict Full Time Salary. Part I, 1965-1968.
39 1 Strict Full Time Salary. Part II, 1965-1968.
39 2 Student Affairs - School of Medicine, 1966-1968.
39 3 Symposium honoring S. J. Singer - Itinerary, August 12, 1995.
39 4 University Hospital - Minority Affairs, 1969.
39 5 William L. Nyhan Honorary Dinner - Photographs Robert Hamburger Master of Ceremonies, November, 1986.

ORIGINS OF THE SCHOOL OF MEDICINE AT UCSD

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Developmental Analysis.
39 6 Correspondence, 1971-1994.
39 7 Typescript drafts with annotations, 1986-1991.
Symposium.
39 8 Typescript draft of transcript, 1984-1986.
39 9 Correspondence, notes, and photograph, 1984-1986.


Finding aid generated: 2013-07-30