Restrictions

All materials, including all videorecordings and unpublished journals, in boxes 14 through 35, are restricted until December 2018 and cannot be used without the written permission of the executor of the estate of D. Carleton Gajdusek.

Abstract

The collection contains the papers of D. Carleton Gajdusek, physician, virologist, and medical researcher who received the 1976 Nobel Prize in medicine for his discoveries concerning a new mechanism for the origin and dissemination of infectious disease. This research originated as Gajdusek sought to understand kuru, a unique and fatal condition whose victims were primarily the women and children of the Fore people of the Eastern Highlands Province of Papua New Guinea. The collection contains bound and unbound published scientific reprints (1957-1996), published and unpublished typescript journals (1955-1996), and videorecordings (1926-1976) filmed by Gajdusek and others. The collection also includes files related to child abuse charges brought against Gajdusek in 1996 by two of the many children he adopted and brought back to the United States from Papua New Guinea and Micronesia and his subsequent plea bargain agreement.

Biography

Daniel Carleton Gajdusek was born in Yonkers, New York, on September 9, 1923. He graduated from the University of Rochester in 1943 before receiving his M.D. from Harvard University in 1946. After residencies at Columbia-Presbyterian Medical Center, Babies Hospital New York, and Children's Hospital Cincinnati, he served as a fellow in pediatrics and infectious diseases at Harvard from 1949-1952. He then served a year as a captain in the Medical Corps at Walter Reed Army Medical Service Graduate School, studying hemorrhagic fever in Korea and in the USSR.

Gajdusek began his Nobel-Prize-winning research in 1955 after holding research positions at Cal Tech, at the Institut Pasteur in Tehran, the University of Maryland, and at the Walter and Eliza Hall Institute of Medicine in Melbourne, Australia. This was the beginning of Gajdusek's decades-long personal and scientific association with the peoples of Papua New Guinea, described in almost daily detail in his journals and in numerous scientific papers and lectures. In Papua New Guinea, Gajudsek co-discovered and provided the first medical description of kuru, a fatal degenerative disorder of the central nervous system unique to the Fore people of the Eastern Highlands Province of that island. Later Gajdusek and others would conclude that the transmission mechanism of kuru originated from the Fore funeral custom of consuming the brains of the deceased. Women and children, kuru's primary victims, were exposed as they prepared and ingested the bodies of infected tribal members.

In 1958, Gajdusek became director of the Study for Child Growth and Development and Disease Patterns in Primitive Cultures, and the Laboratory of Slow, Latent, and Temperate Virus Infections at the National Institutes of Health (NIH) in Maryland. In 1970, he also became chief of NIH's Laboratory of Central Nervous System Studies. While director of these laboratories, Gajdusek also travelled repeatedly back to Papua New Guinea, and around the world, doing additional research and giving lectures and speeches on Kuru and his "slow virus" research.

Gajdusek's long research career at the National Institutes of Health ended in 1996, when he was charged with child abuse. Gajdusek's case never went to trial because he entered a plea agreement that required him to plead guilty to two counts of child abuse, serve nine months in the Frederick County Adult Detention Center (Maryland) and five years probation. Additionally he had to agree not to travel with any unrelated minor. He was permitted to leave the United States and subsequently lived in Europe, continuing to work and edit his yet-to-be published journals, until his death in Norway.

Biographies about Gajdusek include his "Autobiography," (an essay written in 1976 at the time of his Nobel Prize Award) available at http://nobelprize.org/nobel_prizes/ medicine/laureates/1976/gajdusek-autobio.html, Richard Rhodes' story of the discovery and interrelatedness of the transmissible spongiform encephalopathies and prions entitled, Deadly Feasts: Tracking the Secrets of a Terrifying New Plague (New York: Simon and Schuster, 1997), and Warwick Anderson's The Collectors of Lost Souls: Turning Kuru Scientists into Whitemen.

Gajdusek died in December 2008.

Scope and Content of Collection

The papers document physician, virologist, and medical researcher D. Carleton Gajdusek's four decades of research on the causes and transmission of kuru, a neurodegenerative disease found among the Fore people of the eastern highlands of Papua New Guinea. The papers include a broad collection of both Gajdusek's and other scientists' early work on kuru in three bound volumes (1957-1966). Included in the collection are numbered reprints (1957-1996) of Gajdusek's research on the transmissible spongiform encephalopathies (TSEs) and other related subjects. The collection also contains Gajdusek's published and unpublished journals (1955-1996) that chronicle his daily activities while on research expeditions throughout the world, videorecordings (1926-1976), catalogs describing their content, which include extensive films of people with kuru victims, as well as other people, activities, and locations in Papua New Guinea. The collection consists solely of photocopied and published materials and does not include any original, handwritten material. The papers are arranged in four series: 1) BIOGRAPHICAL MATERIALS, 2) WRITINGS, 3) VIDEORECORDINGS, and 4) LEGAL FILES.

SERIES 1: BIOGRAPHICAL MATERIALS

The BIOGRAPHICAL MATERIALS series contains two bound volumes which include Gajdusek's abbreviated and full curriculum vitae, lists of family, friends, adopted children, reprint mailing recipients, archival correspondents, published and unpublished journals, and numbered reprints.

SERIES 2: WRITINGS

The WRITINGS series is arranged in three subseries: A) Kuru Collected Writings, B) Reprints, and C) Journals.

A) The Kuru Collected Writings subseries contains three bound volumes of papers (1957-1966) by Gajdusek and other scientists documenting the initial discovery, possible causes, and various investigations surrounding kuru, including Igor Klatzo's comparison of Kuru to Creutzfeldt-Jakob disease in humans, William J. Hadlow's letter to the Lancet comparing kuru to scrapie in sheep, investigations of epidemiology, and early consideration of the cannibalism theories of Robert M. and Shirley (now Lindenbaum) Glasse. Each volume begins with a numbered index in chronological order.

B) The Reprints subseries gathers three bound volumes of Gajdusek's later papers (1980-1985), beginning with a numbered index. Also included are two hundred and thirty-two unbound reprints (1957-1996) by Gajdusek, alone and with others, published both before and after the bound volumes. In all cases the reprints are arranged chronologically by reprint number.

C) The Journals subseries contains typescript bound copies of Gajdusek's daily journals from his numerous expeditions around the world. Seventeen of the journals (1955-1970 plus a section of Gajdusek's 1993 journal) are published and unrestricted, and sixteen journals are restricted and unpublished (1955-1996). Some of the journals are edited and contain illustrations and photographs.

SERIES 3: VIDEORECORDINGS

The VIDEORECORDINGS series includes VHS transfers of original clinical demonstration and research films pertaining to Gajdusek's work in Papua New Guinea. The series begins with the five-volume catalog of the Central Nervous System Studies Laboratory (CNSSL) Medical Ethnographic Film Archives. Many of the films described in the catalog are included in this series. The folder descriptions for films represented in the catalog include their corresponding catalog numbers. The videorecordings include all 25 parts of Kuru: A Comprehensive Assembly of All Known Kuru Cinema of Clinical Aspects of Kuru. The series contains a 1970 reprint by Gajdusek that details the first seventeen reels of Kuru film, and includes a table listing the filmers, dates of filming, footage length, and number of Kuru patients filmed. The series also includes Parts 1-3 and 6-7 of Nutrition of the Fore People of New Guinea. In addition to films directly related to Gajdusek's research, the series includes narrated film documenting Matthew W. Stirling's 1926-1927 expedition to New Guinea. Materials in the series are arranged alphabetically by title and are restricted.

SERIES 4: LEGAL FILES

The LEGAL FILES series contains Gajdusek's personal documentation regarding the charges of child molestation brought against him in 1996. The material consists of photocopies of letters and petitions of support from scientists, Papua New Guinean and Micronesian children who lived with him and some of whom were adopted by him, and other citizens and officials of Papua New Guinea. These documents were used to initially support Gajdusek against the charges and later to help convince the judge to accept the plea agreement the parties had negotiated. Also included is correspondence relating to the plea agreement that he entered with the State of Maryland, the United States Attorney's concurrence, an FBI memorandum of an interview with a former scientific colleague who reported his suspicions regarding possible child abuse, press clippings, and documentation of his scientific contributions. This material is restricted until 2018.

BIOGRAPHICAL MATERIALS

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1 1 Correspondents and mailing lists - Bound photocopies, 1997.
1 2 Curricula vitae, lectures and awards, journals, and bibliography - Bound photocopies, 1997.

WRITINGS

Kuru Collected Writings

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1 3 #1-52. Papers by Gajdusek and others, 1957 - 1961.
2 1 #53-103. Papers by Gajdusek and others, 1962 - 1964.
3 1 #104-162. Papers of Gajdusek and others, 1964 - 1966.
Box Folder Oversize
Collected Papers of D. Carleton Gajdusek.
4 1 #410-529, 1980 - 1981.
5 1 #530-627, 1982 - 1983.
6 1 #628-730, 1984 - 1985.
7 1 70. Ethnopediatrics as a Study of Cybernetics of Human Development, 1963.
7 2 83. The Composition of Musics for Man Or Decoding from Primitive Cultures the Scores for Human Behavior, 1963.
7 3 90. Factors Governing the Genetics of Primitive Human Populations, 1964.
7 4 142. Drawings by Children in Primitive Cultures, 1969.
7 5 162. Physiological and Psychological Characteristics of Stone Age Man, 1970.
7 6 320.1 Studies of Scrapie in Cell Culture, Cell-Fusing Properties of the Scrapie and CJD Viruses ..., 1977.
7 7 320.2 Simultaneous Density Gradient and Bonding of Scrapie Mouse Brain in Cesium Chloride, Sucrose, ..., 1977.
7 8 325. Urgent Opportunistic Observations: The Study of Changing, Transient and Disappearing Phenomena ..., 1977.
7 9 614. Prologo - Reprint in Spanish, 1983.
7 10 615. Bibliography of Hemorrhagic Fever with Renal Syndrome (Muroid Virus Nephropathy), 1983.
7 11 732. Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia on Guam: A 30-year Evaluation of Clinical ..., 1986.
7 12 739. Pathogenesis of Experimental Hantaan Virus Infection in Laboratory Rats, 1986.
7 13 744. Treponematoses and Tropical Spastic Paraparesis, 1986.
7 14 745. Newer Data on the Inactivation of Scrapie Virus or Creutzfeldt-Jakob Disease Virus in Brain Tissue, 1986.
7 15 747. Newer Data on the Inactivation of Brain Tissue Infected with the Viruses of Scrapie or ..., 1986.
7 16 751. Abnormal Proteins in the Cerebrospinal Fluid of Patients with Creutzfeldt-Jakob Disease, 1986.
7 17 752. Neuropathologic Verification of Creutzfeldt-Jakob Disease in the Exhumed American Recipient of ..., 1986.
7 18 753. Familial Myoclonic Dementia Masquerading as Creutzfeldt-Jakob Disease, 1986.
7 19 754. Intraneuronal Co-Localization of Silicon with Calcium and Aluminum in Amyotrophic Lateral Sclerosis ..., 1986.
7 20 755. Hypothesis: AIDS Encephalopathy is Due to Primary and Persistent Infection of the Brain with ..., 1986.
7 21 760. Histochemical Staining and X-Ray Microanalytical Imaging of Aluminum in Amyotrophic Lateral Sclerosis..., 1986.
7 22 763. On the Uniform Source of Amyloid in Plaques, Tangles and Vascular Deposits, 1986.
7 23 764. Calcium Aluminum Silicon Deposits in Neurons Lead to Paired Helical Filaments Indentical to Those ..., 1986.
7 24 766. Transmission of Creutzfeldt-Jakob Disease from Formalin-Fixed, Paraffin-Embedded Human Brain Tissue, 1986.
7 25 769. Chronic Dementia Caused by Small Unconventional Viruses Apparently Containing No Nucleic Acid, 1986.
7 26 770. Bibliography of Viliuisk Encephalomyelitis in the Iakut People of Siberia, 1986.
7 27 776. Isolation, Characterization and Chromosomal Localization of Human Brain cDNA Clones Coding for ..., 1987.
7 28 777. Serological Survey of Prospect Hill Virus Infection in Indigenous Wild Rodents in the USA, 1987.
7 29 779. Characterization and Chromosomal Localization of a cDNA Encoding Brain Amyloid of Alzheimer's Disease, 1987.
7 30 781. Amyloid Gene Duplication in Alzheimer's Disease and Karyotypically Normal Down Syndrome, 1987.
7 31 782. Experimental Scrapie as a Model for Neuroaxonal Dystrophy, 1987.
7 32 783. Cytoskeletal Proteins Forming Amyloid-Like Structures In Vitro, 1987.
7 33 784. Mouse Homolog of the Human Amyloid Beta Protein (AD-AP) Gene is Located on the Distal End of Mouse ..., 1987.
7 34 785. Amyloid of Neurofibrillary Tangles of Guamanian Parkinsonism-Dementia and Alzheimer Disease Share ..., 1987.
7 35 791. Intra-Blood-Brain Barrier Synthesis of Human Immunodeficiency Virus Antigen and Antibody in Humans ..., 1987.
7 36 825. Studies of the CNS in Chimpanzees Persistently Infected with Human Immunodeficiency Virus, 1987.
7 37 826. Tropical Spastic Paraparesis - The Possible Aetiological Role of the Human T-Cell Leukemia/Lymphoma ..., 1987.
7 38 827. Isolation, Characterization and Chromosomal Localization of Human Brain cDNA Clones Coding for ..., 1987.
7 39 828. Immunocytochemical Studies of Neurofibrillary Tangles in Amyotrophic Lateral Sclerosis and ..., 1987.
7 40 829. Polypeptide Sequence of the Neurofibrillary Tangles in Guamanian Parkinsonism-Dementia, 1987.
7 41 833. Transmissible Dementias and Other Brain Disorders Caused by Unconventional Viruses: Relationship ..., 1987.
7 42 834. Virus Infection in Aetiopathogenesis of Motor Neurone Disease: A Hypothesis for a Final Common Path ..., 1987.
7 43 837. Isolation, Characterization, and Chromosomal Localization of a Human Brain cDNA Clone Coding for ..., 1987.
7 44 838. Isolation, Characterization, and Chromosomal Localization of a Human Brain cDNA Clone Coding for ..., 1987.
7 45 839. Extrathecal and Intrathecal IgG Responses to the AIDS Virus LAV/HTLV-III in Experimental Infection ..., 1987.
7 46 840. Induction in Chimpanzees of Antibodies Inhibiting Receptor-Mediated Cell Fusion by HIV Glycoprotein, 1987.
7 47 842. Hemorrhagic Fever with Renal Syndrome: Global Epidemiology and Ecology of Hantavirus Infection, 1987.
7 48 843. Transmissible and Nontransmissible Dementias: Distinction Between Primary Cause and Pathogenic ..., 1988.
7 49 844. Differential Regulation of Amyloid-Beta-Protein mRNA Expression within Hippocampal Neuronal ..., 1988.
7 50 845. Cervical Lymphoblastic Lymphoma in an Aged Guinea Pig, 1988.
7 51 846-847. Alternative cDNA Clones of Amyloid Beta Protein Encode Protease Inhibitor, 1988.
Includes "Etiology Versus Pathogenesis: the Causes of Post-Translational Modifications of Host Specified Brain Proteins to Amyloid Configuration," 1988.
7 52 849. Tubulovesicular Structures in Experimental Creutzfeldt-Jakob Disease and Scrapie, 1988.
7 53 850. Biological Properties of Scrapie Agent and Relationship with Scrapie Associated Proteins, 1988.
7 54 851. White Matter Ultrastructual Pathology in Experimental Creutzfeldt-Jakob Disease in Mice, 1988.
7 55 852. Cellular Localization of Messenger RNA Encoding Amyloid-Beta-Protein in Normal Tissue and in ..., 1988.
7 56 854. Tropical Spastic Paraparesis in Colombia, 1988.
7 57 855. Pathological and Immunological Observations on Tropical Spastic Paraparesis in Patients from Jamaica, 1988.
7 58 862. Evidence that DNA is Present in Abnormal Tubulofilamentous Structures Found in Scrapie, 1988.
7 59 865. A New Case of Creutzfeldt-Jakob Disease Associated with Human Growth Hormone Therapy in New Zealand, 1988.
7 60 866. Intracerebral Inoculation of Experimental Animals with Brain Tissue from Patients with Schizophrenia, 1988.
7 61 868. Cycads and Amyotrophic Lateral Sclerosis/Parkinsonism Dementia - Contains author's protest regarding editorial alteration of the original title and second sentence, 1988.
7 62 871. Proteinuria in Monkeys Infected with Prospect Hill Virus, 1988.
7 63 872. Hantavirus Infections in Humans and Commensal Rodents in Singapore, 1988.
7 64 873. High Prevalence Rates of Human T-Lymphotropic Virus Type I (HTLV-I) Infection in Isolated ..., 1988.
7 65 875. Antibodies to HTLV-1 in Populations of the Southwestern Pacific, 1988.
7 66 878. Tropical Myeloneuropathies - a New Aetiology, 1988.
7 67 886. Experimental Models of Metal-Induced Neurofibrillary Degeneration, 1988.
7 68 887. Cellular and Molecular Biology of Neurofibrillary Degeneration in Amyotrophic Lateral Sclerosis and ..., 1988.
7 69 888. Hemorrhagic Fever with Renal Syndrome in Yugoslovia: Detection of Hantaviral Antigen and Antibody ..., 1988.
7 70 891. Histochemical and X-Ray Microanalytical Localization of Aluminum in Amyotrophic Lateral Sclerosis ..., 1988.
7 71 892. Experimental Hantavirus Infection in Nonhuman Primates, 1988.
7 72 893. Hemorrhagic Fever with Renal Syndrome: A Historical Perspective and Review of Recent Advances, 1988.
7 73 894. Comparative Trace-Elemental Study on Amyotrophic Lateral Sclerosis (ALS) and Parkinsonism-Dementia ..., 1988.
7 74 895. Amyloidoses of Brain: Transmissible and Non-Transmissible Dementias, 1989.
7 75 896. Neuronal Degeneration and Neurofilament Accumulation in the Trigeminal Ganglia in Creutzfeldt-Jakob ..., 1989.
7 76 897. Immunocytochemical Characterization of Neurofibrillary Tangles in Amyotrophic Lateral Sclerosis and ..., 1989.
7 77 899. HTLV-I Positive Spastic Paraparesis in a Temperate Zone, 1989.
7 78 901. Comparison of a Human T-Cell Lymphotropic Virus Type 1 Strain from Cerebrospinal Fluid of a ..., 1989.
7 79 904. Nucleus Basalis of Meynert in Parkinsonism-Dementia of Guam: A Morphometric Study, 1989.
8 1 907. HTLV-1 Myeloneuropathy in the Solomon Islands, 1989.
8 2 908. No MSP1 Polymorphism in the Open Reading Frame of the PRP Gene in Patients with Familial Cruetzfeldt..., 1989.
8 3 909. Bone Mass in Guamanian Patients with Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia, 1989.
8 4 910. Scrapie-Induced Diabetes Mellitus in Hamsters, 1989.
8 5 911. Dimethylsulfoxide (DMSO) has No Therapeutic or Prophylactic Effect in Hamsters Inoculated ..., 1989.
8 6 912. Patients with Creutzfeldt-Jakob Disease and Kuru Lack the Mutation in the PRIP Gene Found in ..., 1989.
8 7 913. Interleukin 1 Regulates Synthesis of Amyloid Beta-Protein Precursor mRNA in Human Endothelial Cells, 1989.
8 8 915. Olivopontocerebellar Atrophy in a Large Iakut Kinship in Eastern Siberia, 1989.
8 9 916. Mutations in Familial Cruetzfeldt-Jakob Disease and Gerstmann-Straussler-Scheinker's Syndrome, 1989.
8 10 917. Serial Ultrastructual Studies of Scrapie in Hamsters, 1989.
8 11 922. Brain Amyloidoses: Precursor Proteins and Amyloids of Transmissible and Non-Transmissible ..., 1989.
8 12 929. Early Clinical Kuru Study has Led to Discovery of Unconventional Slow Viruses as Infectious Amyloid ..., 1990.
8 13 930. Coexistence of Creutzfeldt-Jakob Disease and Alzheimer's Disease in the Same Patient, 1990.
8 14 931. Virus Isolation Confirms Serological Data of High Prevalance of HTLV-1 Infection in New Guinea, 1990.
8 15 932. Male Pseudohermaphroditism Caused by 5 Alpha-Reductase Deficiency in the Simtari Anga ..., 1990.
8 16 933. Reevaluation of the Ultrastructual Pathology of Experimental Creutzfeldt-Jakob Disease, 1990.
8 17 934. Resistance of Scrapie Infectivity to Steam Autoclaving After Formaldehyde Fixation and Limited ..., 1990.
8 18 935. Subcellular Distribution and Physicochemical Properties of Scrapie-Associated Precursor Protein ..., 1990.
8 19 936. Scrapie Infectivity and Prion Protein are Distributed in the Same pH Range in Agarose Isoelectric ..., 1990.
8 20 937. Scrapie-Associated Precursor Proteins: Antigenic Relationship Between Species and ..., 1990.
8 21 938. Immunohistochemical Localization of Prion Protein in Spongiform Encephalopathies and Normal Brain ..., 1990.
8 22 939. Models of Environmentally Induced Neurological Disease: Epidemiology and Etiology of Amyotrophic ..., 1990.
8 23 940. Interlukin-1 Immunoreactivity in Primary Rat Cortical Neurons and Astrocytes, 1990.
8 24 941. Spread of Creutzfeldt-Jakob Disease Virus Along Visual Pathways After Intraocular Inoculation, 1990.
8 25 945. Detection of Measles Virus Genomic Sequences in SSPE Brain Tissue by the Polymerase Chain Reaction, 1990.
8 26 947. A Simple and Effective Method for Inactivating Virus Infectivity in Formalin-Fixed Tissue Samples ..., 1990.
8 27 948. Paradoxes of Aspiration for and of Children in Primitive and Isolated Cultures, 1990.
8 28 949. Creutzfeldt-Jakob Disease and Kuru Patients Lack a Mutation Consistently Found in the ..., 1990.
8 29 950 & 957. Identical Mutation in Unrelated Patients with Creutzfeldt-Jakob Disease, 1990.
Includes "Mutation in Codon 200 of Scrapie Amyloid Protein Gene in Two Clusters of Cruetzfeldt-Jakob Disease in Siberia," 1990.
8 30 954. PRIP Gene Mutations in Transmissible Spongiform Encephalopathies, 1990.
8 31 955. Molecular Mass, Biochemical Composition and Physicochemical Behavior of the Infectious Form of ..., 1990.
8 32 956. Amyloid of Neurofibrillary Tangles of Guamanian Amyotrophic Lateral Sclerosis Contains Low Molecule ..., 1990.
8 33 958. Conservation of Infectivity in Purified Fibrillary Extracts of Scrapie-Infected Hamster Brain After ..., 1990.
8 34 959. Isolation of HTLV-1 From Members of a Remote Tribe in New Guinea, 1990.
8 35 961. High Prevalence of Human T-Lymphotrophic Virus Type 1 Infection in Isolated Populations in the ..., 1990.
8 36 963. GLI Agenti Di Scrapie - Kuru - CJD - BSE, Quali Polipeptidi Inferttanti: Ipotesi Della Loro Sintesi ... - Reprint in Italian, 1990.
8 37 964. Subacute Spongiform Encephalopathies: Transmissible Cerebral Amyloidoses Caused by Unconventional ..., 1990.
Reprint of "Chapter 80" from the second edition of Virology, edited by B.N. Fields et al.
8 38 969. Brain Amyloidoses: Precursor Proteins and the Amyloids of Transmissible and Non-Transmissible ..., 1990.
8 39 970. Raymond Pearl Memorial Lecture, 1989: Cultural Practices as Determinants of Clinical Pathology ..., 1990.
8 40 971. Human T-Lymphotropic Virus Type 1: A Retrovirus Causing Chronic Myeloneuropathies in Tropical ..., 1990.
8 41 973. Modification of Host Precursor Proteins to Amyloid Fibrils in Alzheimer's Disease, 1990.
8 42 974. Dermatoglyphics of the Isolated Kapinganarangese of Micronesia, 1990.
8 43 975. Tropical Spastic Paraparesis and HTLV-1 Associated Myelopathy -- Clinical and Laboratory Diagnosis, 1990.
8 44 977. Temporal Expression of Amyloid Precursor Protein mRNA in Vitro in Dissociated Hippocampal Neuron ..., 1990.
8 45 978. In Situ Hybridization Detection in HTLV-1 RNA in Peripheral Blood Mononuclear Cells of TSP/HAM ..., 1991.
8 46 984. Survival of Scrapie Virus after 3 Year's Interment, 1991.
8 47 989. Characterization of a Variant of Human T-Lymphotropic Virus Type 1 Isolated from a Healthy Member of ..., 1991.
8 48 990. New Mutation in Scrapie Amyloid Precursor Gene (at Codon 178) in Finnish Creutzfeldt-Jakob Kindred, 1991.
8 49 991. Human T-Lymphotropic Virus Type 1 Infection in the Solomon Islands, 1991.
8 50 993. Clinical and Molecular Genetic Study of a Large German Kindred with Gerstmann-Straussler-Scheinker ..., 1991.
8 51 994. Differences in the Membrane Interaction of Scrapie Amyloid Precursor Proteins in Normal and Scrapie ..., 1991.
8 52 995. Verification of HTLV-1 Infection in the Solomon Islands by Virus Isolation and Gene Amplification, 1991.
8 53 997. Detection of Flaviviruses by Reverse Transcriptase Polymerase Chain Reaction, 1991.
8 54 998. Topographic Distribution of Scrapie Amyloid-Immunoreactive Plaques in Chronic Wasting Disease ..., 1991.
8 55 999. A Cluster of Male Pseudohermaphrodites with 5 Alpha-Reductase Deficiency in Papua New Guinea, 1991.
8 56 1000. Detection of Hantavirus RNA in Tissues of Experimentally Infected Mice Using Reverse Transcriptase ..., 1991.
8 57 1003. Retrovirus HTLV-1 en Chile: Estudio en 140 Enfermos Neurologicos - Reprint in Spanish, 1990.
8 58 1004. Increased Multimeric Mitochondrial DNA in the Brain of Scrapie-Infected Hamsters, 1991.
8 59 1007. Highly Divergent Molecular Variants of Human T-Lymphotropic Virus Type 1 from Isolated Populations ..., 1991.
8 60 1009. In Vitro Detection of Cytokines in Mononuclear Cell Cultures from Patients Affected with HTLV-1 ..., 1992.
8 61 1011. Monocyte Macrophage Abnormalities in HTLV-1 Infection, 1992.
8 62 1012. Novel Mutation in the PRNP Amyloid Precursor Gene Co-Segregates with the Creutzfeldt-Jakob Disease ..., 1991.
8 63 1013. A New Mutation (At Codon 178) in the PRNP Amyloid Precursor Gene Co-Segregates with Creutzfeldt ..., 1991.
8 64 1014. Phenotype Expression of Different Mutations in Transmissible Familial Creutzfeldt-Jakob Disease, 1991.
8 65 1015. Creutzfeldt-Jakob Disease Associated with the PRNP Codon 200 LYS Mutation: An Analysis of 45 Families, 1991.
8 66 1016. Familial Creutzfeldt-Jakob Disease in Finland: Epidemiological, Clinical, Pathological and ..., 1991.
8 67 1017. PrP Amyloid Plaques in Creutzfeldt-Jakob Disease of Short Duration: Immunohistochemical Studies of ..., 1991.
8 68 1019. Transmissible Amyloidoses: Genetical Control of Spontaneous Generation of Infectious Amyloid ...", 1991.
8 69 1020. Molecular Genetics of Familial Creutzfeldt-Jakob Disease in France, 1991.
8 70 1021. Transthyretin Amyloidoses of Familial Amyloidotic Polyneuropathy as a Paradigm for the ..., 1991.
8 71 1022. The Life of the Mind, 1991.
8 72 1025. Transmissible Familial Creutzfeldt-Jakob Disease Associated with Five, Seven and Eight Extra ..., 1991.
8 73 1029. Chapter 12: Virologic Studies in Chronic Encephalitis, 1991.
8 74 1036. Neuronal Autophagic Vacuoles in Experimental Scrapie and Creutzfeldt-Jakob Disease, 1992.
8 75 1037. Atypical Creutzfeldt-Jakob Disease in an American Family with an Insert Mutation in the PRNP ..., 1992.
8 76 1039.1 Creutzfeldt-Jakob Disease Cosegregates with the Codon 178 ASN PRNP Mutation in Families of ..., 1992.
8 77 1039.2 Phenotypic Characteristics of Familial Creutzfeldt-Jakob Disease Associated with the Codon 178 ..., 1992.
8 78 1040. Transmission of Spongiform Encephalopathy from a Creutzfeldt-Jakob Disease (CJD) Patient of Jewish ..., 1992.
8 79 1042. Co-Existence of HTLV-1 and HTLV-2 Infection Among the Wayuu Indians of Colombia, 1992.
8 80 1044. Ultrastructual Pathology of Axons and Myelin in Experimental Scrapie in Hamsters and Bovine ..., 1992.
8 81 1045. In Vitro Detection of Cytokines in Mononuclear Cell Cultures from Patients Affected with HTLV-1 ..., 1992.
8 82 1046. Monocyte Macrophage Abnormalities in HTLV-1 Infection, 1992.
8 83 1055. Viliuisk Encephalomyelitis in the Iakut People of Siberia, 1992.
8 84 1055.1 Bibliography of Viliuisk Encephalomyelitis in the Iakut (Sakha) People of Siberia, 1992.
8 85 1057. An Insert Mutation in the Chromosome 20 Amyloid Precursor Gene in a Gerstmann-Straussler- ..., 1992.
8 86 1062. Fatal Familial Insomnia and Familial Creutzfeldt-Jakob Disease: Disease Phenotype Determined ..., 1992.
8 87 1063. Familial Creutzfeldt-Jakob Disease in Chile is Associated with the Codon 200 Mutation of the PRNP ..., 1992.
8 88 1066. Coexistence of Human T-Lymphotropic Virus Type I and II Among the Wayuu Indians from the Guajira ..., 1992.
8 89 1066.1 [?] Human Retroviruses Among Amerindian Populations of Colombia, 1992.
8 90 1068. Lack of JC Viral Genomic Sequences in Multiple Sclerosis Brain Tissue by Polymerase Chain Reaction, 1992.
8 91 1069. Kuru and Scrapie, 1992.
8 92 1070. Genetic Control of De Novo Conversion to Infectious Amyloids of Host Precursor Proteins: Kuru - ..., 1992.
8 93 1071. Scientific Responsibility, 1992.
8 94 1072. Foreword - Reprint from Human Biology in Papua New Guinea: The Small Cosmos, edited by Robert D. Attenborough and Michael P. Alpers, 1992.
8 95 1075. The Molecular Genetics of Human Transmissible Spongiform Encephalopathy, 1992.
8 96 1076. Belgrade Virus: A New Hantavirus Causing Severe Hemorrhagic Fever with Renal Syndrome in Yugoslavia, 1992.
8 97 1080. Real and Imagined Clinicopathological Limits of 'Prion Dementia', 1993.
9 1 1081. Creutzfeldt-Jakob Disease Infectivity of Growth Hormone Derived from Human Pituitary Glands, 1993.
9 2 1084. Long-Term Observations of Human Immunodeficiency Virus-Infected Chimpanzees, 1993.
9 3 1085. Synthetic Peptide Corresponding to Different Mutated Regions of the Amyloid Gene in Familial ..., 1993.
9 4 1088. Tumour Necrosis Factor-Alpha Produces Creutzfeldt-Jakob Disease-Like Lesions in Vivo, 1993.
9 5 1090. IL-2R, CD4 and MHC Class II Antigen Expression by Human T-Cell Leukemia Virus I (HTLV-1) Infected ..., 1993.
9 6 1092. Conformational Transitions, Dissociation, and Unfolding of Scrapie Amyloid (Prion) Protein, 1993.
9 7 1093. Secondary Structure of Proteins Associated in Thin Films, 1993.
9 8 1094. Genetically Distinct Hantavirus in Deer Mice, 1993.
9 9 1095. Genetic Control of Nucleation and Polymerization of Host Precursors to Infectious Amyloids in the ..., 1993.
9 10 1097. A New (Two-Repeat) Octapeptide Coding Insert Mutation in Creutzfeldt-Jakob Disease, 1993.
9 11 1098. Human Retroviruses in Amerindians of Colombia: High Prevalence of Human T Cell Lymphotropic Virus ..., 1993.
9 12 1101. Transmission of Human Spongiform Encephalopathies in Experimental Animals: Comparison ..., 1993.
9 13 1105. Transmissible Amyloidoses of the Brain, 1993.
9 14 1106. The Spongiform Vacuole - the Hallmark of Slow Virus Disease, 1993.
9 15 1107. Astrocytic Changes, 1993.
9 16 1108. Immunohistory of Astrocytic Reaction, 1993.
9 17 1109. Neuroaxonal Dystrophy in Unconventional Slow Virus Disease, 1993.
9 18 1110. The Amyloid Plaque, 1993.
9 19 1112. Tubulovesicular Structures, 1993.
9 20 1116. Neurofibrillary Tangles of Guamanian Amyotrophic Lateral Sclerosis, Parkinsonism-Dementia ..., 1993.
9 21 1118. Molecular Genetic Testing of a Fetus at Risk of Gerstmann-Straussler-Scheinker Syndrome, 1994.
9 22 1119. In Situ PCR: Detection of Persistent and Latent Viruses Within the Central Nervous System, 1994.
9 23 1120. Iatrogentic Creutzfeldt-Jakob Disease: An Example of the Interplay Between Ancient Genes and ..., 1994.
9 24 1122. Attempts to Detect Influenza Virus in Postencephalitic Parkinsonism by In Situ PCR, 1994.
9 25 1123. Fatal Familial Insomnia and Familial Creutzfeldt-Jakob Disease: Different Prion Proteins ..., 1994.
9 26 1127. Autosomal Dominant Spinocerebellum Ataxic (SCA) in a Siberian Founder Population: Assignment to ..., 1994.
9 27 1127.2 [?] Cellular Localization of Poliovirus in the Spinal Cord During Acute Poliomyelitis, 1994.
9 28 1130. Tumor Necrosis Factor Production in HTLV-1 Infected Monocytes/Macrophages, 1994.
9 29 1134. Fatal Familial Insomnia, 1994.
9 30 1135. Cellular Localization of Measles Virus in SSPE by In Situ PCR Enhanced Detection of Widespread ..., 1994.
9 31 1136. Neuronal Cell Death is Not Caused by Apoptosis in CJD, 1994.
9 32 1137. Hot Start Nested Polymerase Chain Reaction In Situ and In Situ Hybridization to Detect Tax Gene ..., 1994.
9 33 1138. Relationship of Microglia and Scrapie Amyloid-Immunoreactive Plaques in Kuru, Creutzfeldt-Jakob ..., 1994.
9 34 1145. R3-R4 Deletion in the PRNP Gene is Associated with Creutzfeldt-Jakob Disease (CJD), 1994.
9 35 1146. Mutation Analysis of Spinocerebellar Ataxia Type 1 (SCA1) in a Large Iakut Kinship of Eastern Siberia, 1994.
9 36 1148. HIV-1 NEF Down-Modulates FC Receptors in Human Monocyte/Macrophage, 1994.
9 37 1152. Human Spongiform Encephalopathy: The National Institutes of Health Series of 300 Cases of ..., 1994.
9 38 1155. Isolation of Pathogenic Hantavirus from White-footed Mouse (Peromyscus leucopus), 1994.
9 39 1156. Nucleating Induction of Infectious Amyloids from Host Precursors, 1994.
9 40 1158. Early Inspiration, 1994.
9 41 1163. Electron Microscopic Findings in Brain of Rocky Mountain Elk with Chronic Wasting Disease, 1994.
9 42 1164. Detection of RNA Virus in Archival Brain Tissue by In Situ RT-PCR Amplification and Labeled-Probe ..., 1994.
9 43 1165. In Situ RT-PCR Amplification in Archival Brain Tissue, 1994.
9 44 1167. Amyotrophic Lateral Sclerosis of Guam: the Nature of the Neuropathological Findings, 1994.
9 45 1171. Neuroaxonal Dystrophy in Experimental Creutzfeldt-Jakob Disease: Electron Microscopical and ..., 1995.
9 46 1172. Creutzfeldt-Jakob Disease with Alzheimer-type A-Beta-Reactive Amyloid Plaques, 1995.
9 47 1174. Cellular Localization of Poliovirus RNA in the Spinal Cord during Acute Poliomyelitis, 1995.
9 48 1175. Prospect Hill Virus: Genetic Diversity and Molecular Phylogeny of an Arvicolid Rodent-Borne Hantavirus, 1995.
9 49 1177. Proliferating Cell Nuclear Antigen Immunohistochemistry in Astrocytes in Experimental ..., 1995.
9 50 1181. Intracerebral Distribution of Infectious Amyloid Protein in Spongiform Encephalopathy, 1995.
9 51 1184. Overexpression of Pro- and Anti-Inflammatory Cytokines by Cultured Keratinocytes from ..., 1995.
9 52 1186. Molecular Phylogeny and Dissemination of Human T-Cell Lymphotropic Virus Type I Viewed Within the ..., 1995.
9 53 1191. Subtle Neurological Signs in 'Asymptomatic' Familial TSP/HAM, 1996.
9 54 96/1. Widespread, Restricted Low Level Measles Virus Infection of Brain in a Case of Subacute Sclerosis ..., 1996.
9 55 96/4. Apoptosis in Glial Tumors as Determined by In Situ Nonradioactive Labeling of DNA Breaks, 1996.
9 56 96/5. Chapter 91 - Infectious Amyloids: Subacute Spongiform Encephalopathies as Transmissible Cerebral ..., 1996.
Box Folder Oversize
9 57 Journals of D. Carleton Gajdusek - Contains typescript photocopies of lists of Gajdusek's published and unpublished journals, 1981 - 1990.
9 58 Correspondence on the Discovery and Original Investigations on Kuru: Smadel-Gajdusek Correspondence, 1955 - 1958, second printing, June 1976.
10 1 Kuru Epidemiological Patrols from the New Guinea Highlands to Papua, August 21 - November 10, 1957.
10 2 New Guinea journal - Contains laid-in list of journals inscribed to Francis Crick, June 10 - August 15, 1959.
10 3 Solomon Islands, New Britain and East New Guinea journal, January 7 - May 6, 1960.
10 4 Journal of Expedition in the Libyan Sahara to Kufra, October 9 - November 14, 1960.
10 5 Journal of an Expedition to the Western Caroline Islands, September 4 - October 1, 1961.
11 1 New Guinea journal, October 2, 1961 - August 4, 1962.
11 2 Melanesian journal, February 22 - July 23, 1963.
11 3 Paraguyan Indian Expeditions to the Guayaki and Chaco Indians, August 25 - September 28, 1963.
11 4 Journal of a trip to the Shepherd Banks and Torres Islands and to Espiritu Santo and Efate in the New Hebrides, November 15 - December 25, 1963.
12 1 Journal of further explorations in the Kuru Region and the Kukukuku Country, Eastern Highlands of Eastern ..., December 25, 1963 - May 4, 1964.
12 2 Journal of an expedition to the Western Caroline Islands, August 26 - October 6, 1964.
12 3 Melanesian Journal: Expedition to New Hebrides, Solomon Islands, Manus, New Britain and New Guinea - Soft-bound with inscription to Francis Crick, January 23 - April 7, 1965.
12 4 Melanesian and Micronesian Journal: Return Expeditions to the New Hebrides, Caroline Islands and New Guinea - Contains laid-in photocopy of partial list of journals, July 29 - December 20, 1965.
13 1 South Pacific expedition - With laid-in 1983 list of Gajdusek journals. First blank page contains a stamp, "Prof. F.H.C. Crick - The Salk Institute", January 26 - May 12, 1967.
This edition was revised and reprinted with an index and illustrations in September 1982.
13 2 Colombian expeditions to the Noanama, Cofan and Ingano Indians, August 22 - September 14, 1970.
13 3 Sections of the 1993 Journal of D. Carleton Gajdusek Relating to Studies of Kuru, Population Genetics and Male Pseudohermaphroditism in Papua New Guinea - and - Rediscovery of Persistent High Incidence Amytrophic Lateral Sclerosis/Parkinsonism Dementia in West New Guinea (Irian Jaya, Indonesia), 1993.
14 1 Australia and New Guinea journals, October 1955 - December 31, 1957.
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14 2 Melanesian, Indonesian, and Malaysian expedition, November 16, 1975 - May 11, 1976.
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14 3 Stumbling Along the Tortuous Road to Unanticipated Nobility. Melanesian, Indonesian, and Malaysian Expedition; Viliuisk Encephalitis in Iakut Siberians; Sojourns with Royalty, November 16, 1975 - December 31, 1976.
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15 1 Journal of a Flight from Nobility in an Attempt, in Latin America and French East Africa, to Recover from..., February 21 - April 28, 1977.
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15 2 Western Pacific journal, January 4 - September 23, 1978.
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15 3 Journal of a Year of Travels and Medical Investigations..., 1982.
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15 4 China Journal With a Circuit Through New Zealand, Australia, Papua New Guinea, Hawaii, and Geneva and Two..., January 4 - April 30, 1983.
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15 5 Duodeca Log: Journal of Twelve Departures From and Return to Prospect Hill, 1988.
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16 1 Decline and Fall of Prospect Hill: The End of a Decade of Manorial Living, 1989.
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16 2 Year of Reentrenchment in a Wonderland of Infectious Amyloids, 1990.
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17 1 Except for Happiness at Rainbow's End, 1991.
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17 2 Studies of Mind, Brain, Sex, and Language: From Tropics to Arctic on Two Hemispheres, 1992.
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18 1 Journal of a Year of Disenchantment, 1994.
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18 2 Journal of a Year of Disentanglement, 1995.
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18 3 Regaining Equanimity, 1996.
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19 1 Ascent to the Zenith Was Magnificent; Denouement Was a Bit Difficult, Part I: Descent to Inferno, January 1 - April 16, 1996.
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VIDEORECORDINGS

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Box Folder Oversize
Catalog of the CNSSL Medical Ethnographic Film Archives, 1996 edition.
20 1 Volume 1. Research Films (1957-1965).
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20 2 Volume 2. Research Films (1966-1978).
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21 1 Volume 3A-B. Deposited Research Films, Special Research Films, and Demonstration Films.
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21 2 Volume 4. Supplement.
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21 3 Volume 5. Master List of Films (Volume 1-4) and Supplemental Index of Films Not Described or Listed in Volumes 1-4.
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22 1-2 Asmat Skills, parts 1 & 2.
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22 3 Asmat Tjitak.
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22 4 Clinical Demonstrations.
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23 1 Exploration of the Kuru Region. People of the Kuru Region, March 1, 1957 - February 1958.
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23 2-3 Kukukuku; Moraei, Simbari, Bulaki, Usirampia, Iambananye, Amdei, Kamal Yanapa, Hakwangi; Exploratory Patrol... Parts 1 & 2, April 29 - May 15, 1962.
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23 4 A Comprehensive Cinema Record of Disappearing Kuru - Reprint detailing the filming of the first 17 reels of Kuru Films. Includes a table of filmers, dates of filming, footage length and number of Kuru patients filmed, 1970.
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Kuru: A Comprehensive Assembly of All Known Kuru Cinema of Clinical Aspects of Kuru, 1957 - 1964.
24 1-4 Parts 1-4.
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25 1-4 Parts 5-8.
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26 1-4 Parts 9-12.
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27 1-4 Parts 13-16.
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28 1 Part 17.
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Kuru: A Comprehensive Assembly of All Known Kuru Cinema of Clinical Aspects of Kuru, 1967 - 1976.
28 2-4 Parts 18-20.
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29 1-4 Parts 21-24.
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30 1 Part 25.
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30 2 Longlong Behavior: Ritual Clownings as a Socially Accepted Pattern of Behavior Disorder, produced and filmed by E.R. Sorenson and D.C. Gajdusek, 1961 - 1964.
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Moraei and Munriri Kukukuku; Ethnopediatric Study, Eastern Highlands, Territory of Papua and New Guinea.
30 3-4 Part 1, cans A & B, January 2 - 26, 1962.
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31 1 Part 2, 1962.
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31 2-3 Moraei and Munriri Kukukuku, Yar-Pawaian, and South Fore; Child Study and Medical and Epidemiological... Parts 1 & 3, April 7-30, 1963.
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Nutrition of the Fore People of New Guinea, 1959-1964.
31 4 Part 1.
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32 1-4 Parts 2-3, 6-7.
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33 1-2 Parts 8-9.
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Stirling New Guinea Expedition, 1926 - 1927.
33 3-4 Parts 1 & 2.
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34 1-3 Parts 3, 4A & 4B.
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34 4 Yagwalye, Iwaia, Hakwangi; The Kukukuku Peoples of the Menyamya Region, East New Guinea, May 1960.
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LEGAL FILES

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Historical Record of the Prosecution, Trial, and Defense of D. Carleton Gajdusek.
35 1-4 Folios I - IV, 1996.
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35 5-6 Folio V, parts 1 & 2, 1997.
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Finding aid generated: 2012-09-27