Abstract

Papers of Herbert Hultgren, cardiologist, mountain climber, researcher in high altitude medicine, and specialist in the study of high altitude pulmonary edema (HAPE). Hultgren and his colleague, Dr. Warren Spickard, were the first to publish a full account of high-altitude pulmonary edema in an English language publication. The papers contain materials related to Hultgren's work in Peru in the early 1960s on HAPE; drafts and production materials for his self-published textbook entitled HIGH ALTITUDE MEDICINE; a complete collection of his reprints; and files related to his important journal articles. The bulk of the collection is concerned with Hultgren's research on high altitude pulmonary edema (HAPE) and preparation of the book HIGH ALTITUDE MEDICINE and contains notebooks, drafts, notes, correspondence, data from experiments and patient observations, and reference articles. Also included are files documenting Hultgren's work on cardiac catheterization and establishment of first catheterization laboratory in Stanford, as well as his observation of cases of severe starvation in concentration camp survivors conducted while he served in Europe with U.S. Medical Corps in the end of the World War II. The papers are arranged in six series: 1) NOTEBOOKS, 2) SUBJECT FILES, 3) JOURNAL ARTICLES, 4) HIGH ALTITUDE MEDICINE - BOOK MATERIALS, 5) MISCELLANEOUS MATERIALS, and 6) REPRINTS.

Biography

Herbert Nils Hultgren was born on August 29, 1917, in Santa Rosa, California. He attended Santa Rosa Junior College and then Stanford University where he graduated in 1939. Hultgren attended the Stanford School of Medicine and graduated in 1943. He served in the U.S. Army in Europe between 1944 and 1945 where he observed starved prisoners from German concentration camps. Before joining the Stanford faculty in 1948, he completed residencies in internal medicine and pathology at Stanford. He attained the rank of professor at Stanford School of Medicine and served as chief of the Cardiology Division at Stanford Medical School and later at the Veterans Administration Hospital, Palo Alto, California. Hultgren designed and established the first cardiac catheterization laboratory in Northern California.

In 1959, Hultgren and his colleague, Dr, Warren Spickard, traveled to Peru and visited the Chulec General Hospital where they encountered high altitude pulmonary edema, known locally as edema of the lungs in newcomers. They reviewed the reports on 41 cases and presented the data in the Stanford Medical Bulletin.

In 1990, Hultgren received the prestigious Albion W. Hewlett Award for excellence in patient care, teaching, and research by his fellow Stanford University faculty members. He served as chairman of the Sub-specialty Board on Cardiovascular Disease of the American Board of Internal Medicine, President of the Association of University Cardiologists, President of the Western Association of Physicians, and was a member of the American Society of Clinical Investigation.

After his retirement, he continued part-time teaching and lecturing until his death in October 1997.

Scope and Content

The papers of Herbert Nils Hultgren (1917-1997), a prominient cardiologist and pioneering researcher in high altitude medicine, document his research in high altitude medicine and cardiac catheterization. The bulk of the collection is related to Hultgren's research on high altitude pulmonary edema (HAPE) and preparation of his book entitled HIGH ALTITUDE MEDICINE. These materials comprise notebooks, subject files, and drafts of chapters. Materials related to his trip to Peru in 1960-1961 include a notebook and transcriptions of two tapes dictated by Hultgren while he was there. Also represented in the collection are materials documenting Hultgren's observations of severe cases of starvation in Nazi concentration camp survivors.

The papers are arranged in six series: 1) NOTEBOOKS, 2) SUBJECT FILES, 3) JOURNAL ARTICLES, 4) HIGH ALTITUDE MEDICINE - BOOK MATERIALS, 5) MISCELLANEOUS MATERIALS, and 6) REPRINTS.

SERIES 1: NOTEBOOKS

The NOTEBOOKS series contains manuscript notes on military medicine and experiments done at the 131st Evacuation and 59th Field Hospitals with the U.S. Army Medical Corps, observations of cases of severe starvation in Nazi concentration camp survivors, laboratory notes on cardiac catheterization and congenital heart disease, and observations of HAPE from a 1961 trip to Peru. The notebooks are organized chronologically.

SERIES 2: SUBJECT FILES

The SUBJECT FILES series, arranged alphabetically, contains research materials related to the study of coronary artery perfusion, high altitude pulmonary edema, hypercholesterolemia, and malnutrition. Included are data sheets, charts, X-rays, correspondence, and figures.

SERIES 3: JOURNAL ARTICLES

The JOURNAL ARTICLES series contains manuscript drafts, correspondence and research materials for selected journal articles.

SERIES 4: HIGH ALTITUDE MEDICINE - BOOK MATERIALS

The HIGH ALTITUDE MEDICINE series contains files that were generated during Hultgren's work on his HIGH ALTITUDE MEDICINE book. The files include correspondence, notes, reference materials, figures, and drafts. The series is arranged in three subseries: A) Research Materials, B) Drafts, and C) Editorial Materials.

A) The Research Materials subseries is arranged by chapter and contains notes, correspondence, and reference articles.

B) The Drafts subseries is also arranged by chapter and contains typescripts for each chapter of the book. Also included are figures, correspondence and reference articles.

C) The Editorial Materials subseries contains correspondence regarding monograph indexing and editorial notes.

SERIES 5: MISCELLANEOUS MATERIALS

The MISCELLANEOUS MATERIALS series contains Hultgren's curriculum vitae and a list of his publications. Also included are files related to a discussion of Hultgren's contribution to the study of HAPE syndrome, and transcriptions of tapes dictated by Hultgren in Peru in 1960 with his commentary on HAPE.

SERIES 6: REPRINTS

The REPRINTS series contains a complete collection of Hultgren's reprints arranged in numerical order.

NOTEBOOKS

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1 1 Physical Diagnosis, 1940.
1 2 Military Medicine, 1945 - 1946.
1 3 Notes on Experiments in the 131st Evacuation and 59th Field Hospitals, 1945 - 1946. Contains notebook, Hultgren's identification card, newspaper clipping, and typescript confession of Franz Ziereis, a concentration camp official.
1 4 Laboratory notes, 1952. Contains notes on cardiac catheterization, congenital heart disease, plans for the opening of cardiac catheterization laboratory, and meeting notes.
1 5 Peru Data Book, 1961. Contains observations of patients and catheter study notes.
1 6 Peru notebooks, 1960 - 1962.
1 7 Peru notebook, 1964.
1 8 Peru notebooks, 1966 - 1967. Also includes Ecuador notebook, 1968.

SUBJECT FILES

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1 9 Charts. Undated.
1 10 Coronary Artery Perfusion, 1969. Contains data sheets.
1 11 Coronary Perfusion (Dog), 1970. Contains notes and X-rays of heart.
2 1 Data sheets and charts. Undated. Contains tables numbered 1 through 54.
2 2 Dugong Heart. Contains correspondence, notes, reference articles, and black-and-white photographs of heart.
2 3 High Altitude Pulmonary Edema - Autopsy Studies and Data. Contains correspondence, notes, and reference materials.
2 4 High Altitude Pulmonary Edema - Fatal cases. Contains letters, data sheets, and Rodman Wilson's report on Problems of Sickness and Rescue at High Altitude.
2 5 High Altitude Pulmonary Edema - Pathology. Contains reprints of articles.
2 6 Hypercholesterolemia - Kahn. Contains correspondence, data sheets, and medical records.
2 7 Malnutrition, 1945. Contains correspondence, notes, and X-rays.
2 8 Photographs. Charts, X-rays, and tables.
2 9 X-rays of injected coronary arteries, 1969. Contains X-rays numbered 1 through 45 and two negatives with notes.

JOURNAL ARTICLES

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2 10 Cardiac Function Following Prosthetic Aortic Valve Replacement, 1969. With H. Hubis and N. Shumway. Contains draft, notes, correspondence, and figures.
2 11 Cardiac Function Following Prosthetic Aortic Valve Replacement, 1969. With H. Hubis and N. Shumway. Contains reference materials.
2 12 Cardiac Function Following Mitral Valve Replacement, 1968. With H. Hubis and N. Shumway. Contains correspondence and drafts.
3 1 Cardiac Function Following Prosthetic Mitral Valve Replacement, 1968. With H. Hubis and N. Shumway. Contains manuscripts, charts, notes, and figures.
3 2 Clinical and Laboratory Observations In Severe Starvation, 1951. Contains manuscripts, typescripts, galley proof, two letters, black-and-white photographs, and a reference article.
3 3 History Of Cardiac Catheterization. Contains typescript, manuscript, and notes.
3 4 History Of Cardiac Catheterization. Contains correspondence and black-and-white photographs. Correspondence dating back to 1958-1959.
3 5 History Of Cardiac Catheterization. Contains reference materials.
4 1 Syndrome Of Patent Ductus Arteriosus With Pulmonary Hypertension, 1953. With A. Selzer, A. Purdy, E. Holman, and F. Gerbode. Contains typescripts.
4 2 Syndrome Of Patent Ductus Arteriosus With Pulmonary Hypertension, 1953. With A. Sezer, A. Purdy, E. Holman, and F. Gerbode. Contains notes, correspondence, and black-and-white photographs.
4 3 Venous Pistol Shot Sounds, 1962. Contains typescripts, manuscripts, notes, and correspondence.
4 4 Venous Pistol Shot Sounds, 1962. Contains charts, reference articles, and negatives.

HIGH ALTITUDE MEDICINE -- BOOK MATERIALS

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Research Materials

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4 5 1. Physiologic Effects of High Altitude. Contains correspondence and reference materials.
4 6 2. Respiration and Pulmonary Function. Contains correspondence and reference materials.
4 7 3. Systematic Circulation. Contains a letter, notes, and reference articles.
4 8 4. Pulmonary Circulation. Contains a letter, notes, and reference articles.
4 9 5. Blood and Plasma Volume. Contains correspondence and reference articles.
5 1 6. Central Nervous System. Contains letters, notes, and reference articles.
5 2 7. Endocrine System. Contains notes and reference materials.
5 3 8. Nutrition and Metabolism. Contains reference materials.
5 4 9. Water, Electrolytes and Acid-Base Balance. Contains notes and reference articles.
5 5 10. Acclimatization. Contains notes and reference articles.
5 6 11. Exercise. Contains a letter and reference articles.
5 7 12. Acute and Subacute Mountain Sickness. Contains notes, letters, and reference articles.
5 8 13. High Altitude Pulmonary Edema. Contains correspondence, notes, and reference articles.
5 9 14. High Altitude Cerebral Edema. Contains correspondence, notes, and reference articles.
6 1 15. Chronic Mountain Sickness. Contains a letter, notes, tables, and reference articles.
6 2 16. Sleep.
6 3 17. Systemic Edema. Contains letters and reference articles.
6 4 19. Headache. Contains letter, notes, and articles.
6 5 20. High Altitude Pulmonary Hypertension. Contains letters and reference materials.
6 6 21. Retinal Hemorrhages. Contains letters, notes, and reference materials.
6 7 22. Syncope. Contains letters, notes, typescripts, and reference materials.
6 8 23. Coronary Artery Disease. Contains letters, notes, and reference articles.
6 9 24. Congenital and Valvular Heart Disease. Contains a letter, notes, and reference materials.
6 10 25. Systemic Hypertension. Contains correspondence, notes, and reference materials.
6 11 26. Sickle Cell Disease. Contains a letter, notes, and reference materials.
6 12 27. Pulmonary Disease. Contains notes and reference materials.
7 1 28. Migraine. Contains a letter, reference materials, and notes.
7 2 29. Sea Level Conditions. Contains letters, notes, and reference materials.
7 3 30. Women and Altitude. Contains a letter, notes, and reference materials.
7 4 High Altitude Man - Notes. Contains letters, notes, and reference materials.
7 5 Appendix 1. Medicolegal Aspects. Contains correspondence, notes, and reference materials.
7 6 Medico-Legal Problems (Clients not Passengers). Contains notes and reference materials.
7 7 Appendix 2. Selected High Altitude Monographs and Proceedings.
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7 8 Table of Contents. Contains drafts, notes, and correspondence.
7 9 Introduction.
7 10 1. Physiologic Effects of High Altitude.
7 11 2. Respiration and Pulmonary Function.
7 12 3. Systemic Circulation.
7 13 4. Pulmonary Circulation.
8 1 5. Blood and Plasma Volume.
8 2 6. Central Nervous System.
8 3 7. Endocrine System.
8 4 8. Nutrition and Metabolism.
8 5 9. Water, Electrolytes and Acid-Base Balance.
8 6 10. Acclimatization.
8 7 11. Exercise.
8 8 12. High Altitude Man.
8 9 12. Acute and Subacute Mountain Sickness.
8 10 12. Acute and Subacute Mountain Sickness.
8 11 12. Acute and Subacute Mountain Sickness.
9 1 13. High Altitude Pulmonary Edema.
9 2 13. High Altitude Pulmonary Edema.
9 3 13. High Altitude Pulmonary Edema. Tables.
9 4 14. High Altitude Celebral Edema.
9 5 15. Chronic Mountain Sickness.
9 6 16. Sleep.
9 7 17. Systemic Edema.
9 8 18. Thromboembolism.
9 9 19. Headache.
9 10 20. High Altitude Pulmonary Hypertension.
9 11 21. Retinal Hemorrhages.
9 12 22. Syncope.
9 13 23. Coronary Artery Disease and Altitude.
9 14 24. Congenital and Valvular Heart Disease.
9 15 25. Systemic Hypertension.
9 16 26. Sickle Cell Disease.
9 17 27. Pulmonary Disease.
9 18 28. Migraine.
10 1 29. Sea Level Conditions.
10 2 30. Women and Altitude.
10 3 Appendix 1. Medicolegal Aspects.
10 4 Appendix 2. Selected High Altitude Monographs and Proceedings.
10 5 Appendix 2. Medications Used For High Altitude Medical Problems. Contains correspondence, notes, drafts, and reference materials.

Editorial Materials

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10 6 Monograph Indexing. Contains correspondence and notes.
10 7 Shirley Taylor Editorial Notes.

MISCELLANEOUS MATERIALS

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10 8 Curriculum Vitae, 2004.
10 9 Hultgren's contributions to and work on high altitude pulmonary edema - discussion, 1960 - 1998. Contains Robert F. Grover, reprint of Hultgren's article "Lung Pathology In High Altitude Pulmonary Edema," transcriptions of tapes dictated by him in Peru in 1960, June 18 and July 23, a letter from Hultgren dated 1962, and a letter from Charles Houston to Hultgren from 1966.
10 10 West, John, 1995 - 1998. Contains correspondence and enclosures. Correspondence concerned with early history of HAPE and Hultgren's contributions to the discussion of HAPE.
10 11 Scientific American Medicine, 1993. Contains correspondence and tables.
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10 12 Numbered Reprints 1-35.
10 13 Numbered Reprints 36-66.
11 1 Numbered Reprints 67-113.
11 2 Numbered Reprints 114-158.
11 3 Numbered Reprints 159-197.



Finding aid generated: 2006-08-24