Abstract

Papers of Bruno Zimm, inventor, educator, and polymer DNA scientist. Professor of chemistry and biochemistry at University of California, San Diego, from 1960 to 1991 and professor emeritus after his retirement in 1991. Zimm is known for his work on understanding the fundamental physical and chemical properties of DNA. His theoretical models helped discover how to measure the size of DNA molecules and their propensity. The papers include numerous scientific articles published in polymer science and biophysical chemistry journals and extensive collection of research influenced subject files. The materials also document his early scientific career with General Electric Company, grant project investigations, and teaching materials in the Department of Chemistry, which he helped establish in 1960. Additionally the papers include correspondence, laboratory research notebooks, and biographical materials.

Biography

Born in Woodstock, New York, on October 31, 1920, Bruno Hasbrouck Zimm grew up in an artistic household with his father, a sculptor and his mother, a writer. His education began at Columbia University, where he earned a bachelor's degree of science in 1941, followed by a master's in 1943, and a Ph.D. in 1944, the latter was under the direction of theoretical chemical physicist, Joseph Mayer, with Zimm's thesis on the vapor pressures of alkali halides and lattice energies. Toward the end of World War II, Zimm participated in war-related research on light scattering by smokes under Victor K. LaMer.

After leaving Columbia University, Zimm briefly taught at Polytechnic Institute of Brooklyn, where he collaborated with polymer scientist Herman Mark. He joined the Department of Chemistry at the University of California, Berkeley, for four years (1946-1950), and taught as visiting faculty at Harvard University. During his tenure at Berkeley, he continued his work on light scattering, which he had developed while at Brooklyn, and invented the "Zimm Plot" for determining both size and shape factors for large molecules. He then worked at General Electric Research Laboratory in Schenectady, New York, for nine years (1951-1960), during which time he continued to study synthetic polymers.

After a brief period as visiting faculty at Yale University, he accepted a position at the University of California, San Diego (1960), where he helped establish the Department of Chemistry, along with Joseph Mayer, Stanley Miller, David Bonner, and Stanley Mills. He remained at UCSD until his death.

After his arrival at UCSD, Zimm began a long-term experimental project to find the true lengths of native DNA molecules. In order to test these theories, in 1963, he and post-doctoral student Don Crothers devised an apparatus to measure the lengths of long polymers using the viscosity of solutions, namely a rotating cylinder viscometer, although the device took about ten years to fully evolve. This research allowed him, with post-doctoral biologist Ruth Kavenoff, to measure for the first time the size of a DNA molecule in an intact fruit fly chromosome. The research concluded that each chromosome was composed of a single densely folded DNA molecule. Later on in his research career, he focused on theoretical schemes for the counter-ion environment around DNA. Zimm also taught courses on macromolecules in the UCSD Department of Chemistry for graduate and undergraduate students.

Zimm was elected to the National Academy of Sciences in 1958 and was a member of the American Academy of Arts and Sciences. He received numerous honors and awards, including the Bingham Medal of the Society of Rheology in 1960, the American Physical Society High-Polymer Physics Prize in 1963, and the National Academy's Award in Chemical Sciences in 1981.

Bruno Zimm died on November 26, 2005.

References used:

Doolittle, Russell. "Bruno H. Zimm (1920-2005)", PROTEIN SCIENCE, 2006, 15:942-944.

Stockmayer, Walter. "Bruno Zimm on His 65th Birthday", MACROMOLECULES, Volume 18, Number 11, 1985.

Scope and Content

The papers of Bruno Zimm, prominent biophysical and polymer chemist, document the scientific career of a leading theoretical inventor and academician in the field of biological and synthetic macromolecules. Well-represented in the collection are his scientific writings; correspondence with notable colleagues, Joseph Mayer and Walter Stockmayer; and science based research files. The papers also include materials generated during his tenure at the General Electric Company and, more prominently, as a founding faculty member of the University of California, San Diego Department of Chemistry. Additional materials include grant applications and correspondence, laboratory notebooks, and biographical documents.

The papers are arranged in eight series: 1) CORRESPONDENCE, 2) WRITINGS BY ZIMM, 3) SUBJECT FILES, 4) GRANT MATERIALS, 5) GENERAL ELECTRIC COMPANY, 6) TEACHING MATERIALS, 7) LABORATORY NOTEBOOKS, and 8) BIOGRAPHICAL MATERIALS.

SERIES 1: CORRESPONDENCE

The CORRESPONDENCE series is arranged in two subseries: A) Alphabetical and B) Chronological. The first subseries contains correspondence between Zimm and researchers, colleagues, and various persons in the scientific community. The second subseries contains chronological correspondence from 1949-1998, generated by Zimm, and includes subsequent response letters.

SERIES 2: WRITING BY ZIMM

The WRITING series includes three subseries: A) Numbered Reprints, B) Unnumbered Reprints, and C) Reviewed By.

A) The Numbered Reprints subseries includes numerically arranged reprints dating from 1944 to 1994.

B) The Unnumbered Writing subseries gathers both published and unpublished manuscripts and reprints not listed with the numbered reprints. The titles are arranged alphabetically.

C) The Reviewed By subseries, arranged by author's name, contains copies of papers submitted by colleagues for review and remarked on by Zimm.

SERIES 3: SUBJECT FILES

The SUBJECT FILES series is arranged in three subseries: A) Award Recommendation Letters, B) Research, and C) Drawings.

A) The materials in the Award Recommendation Letters subseries are letters written by Zimm recommending colleagues' accomplishments for national awards.

B) The Research files subseries, arranged alphabetically, includes source materials related to Zimm's research interests, including several folders on light scattering theory and electrophoresis projects. The files contain research notes, calculations, correspondence, and laboratory data.

C) The Drawings subseries represents miscellaneous illustrations and renderings of prototype devices, scientific data charts and graphs.

SERIES 4: GRANT MATERIALS

The GRANT MATERIALS are grant and patent applications for the UCSD-funded project for the device separator for large polymer molecules, which Zimm co-investigated with Kenneth Dill, beginning in 1979. The files also include the theoretical light scattering equation research innovated by Zimm in 1948, and later funded by the Wyatt Technology Corporation to construct a device to plot the equations in 1986. The materials are arranged alphabetically.

SERIES 5: GENERAL ELECTRIC COMPANY

The GENERAL ELECTRIC COMPANY series documents Zimm's early scientific work at the General Electric Research Laboratory as a physical chemist. The files contain reports and laboratory memos Zimm authored regarding his research into polymer solutions. The papers are arranged alphabetically by title.

SERIES 6: TEACHING MATERIALS

Zimm helped establish the UCSD Department of Chemistry in 1960 and taught courses in biochemistry and macromolecules until his retirement in 1991. The files contain curriculum materials such as lecture notes, handouts, exams, and the student laboratory experiments for the measurements of DNA molecules. The materials are arranged alphabetically by course title.

SERIES 7: LABORATORY NOTEBOOKS

The LABORATORY NOTEBOOKS series consists of notebooks relating to Zimm's research at the General Electric Research Laboratory from 1950-1958 and in the Department of Chemistry at University of California, San Diego. The early notebooks supported statistical data reflecting experiments involving methods of determining molecular weights and shapes. His UCSD research diary notebooks reflect the long-term experimental DNA project utilizing an apparatus to measure the viscosity of solutions. The notebooks are arranged chronlogically.

SERIES 8: BIOGRAPHICAL MATERIALS

Arranged alphabetically, the BIOGRAPHICAL MATERIALS series contains personal history documents including biographies, curriculum vitae, Columbia University education materials, photographs of Zimm, awards, newspaper articles, miscellaneous memorabilia, and an interview of Zimm by the Beckman Center for the History of Chemistry.

CORRESPONDENCE

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Alphabetical

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1 1 A-Miscellaneous.
1 2 Auer, Peter L., 1975.
1 3 B-Miscellaneous.
1 4 Barkley, Dicky, 1976 - 1979.
1 5 Benham, Craig J., 1992 - 1993.
1 6 Bustamante, Carlos, 1997.
1 7 C-Miscellaneous.
1 8 Calladine, Chris, Professor, 1995. Includes photograph of Bruno Zimm, 1995.
1 9 The Center for History of Chemistry (Colleen Wickey), 1987 - 1994.
1 10 Chu, Ben, 1992 - 2001.
1 11 D-Miscellaneous.
1 12 Dayantis, Jean, 1987 - 1988.
1 13 Debye, Peter.
1 14 Dill, Ken A., 1983 - 1984.
1 15 Doi, Masao, 1991 - 1993.
1 16 Doolittle, Russell, 2000.
1 17 Doty, Paul, 1965.
1 18 Douglas, Jack F., 1984.
1 19 Eirich, Fred R. Includes 'Remembering Times Past', 1992.
1 20 F-Miscellaneous.
1 21 Finke, John.
1 22 Fixman, Marshall, 1966 - 1996.
1 23 Frisch, Harry L., 1979.
1 24 G-Miscellaneous.
1 25 H-Miscellaneous.
1 26 Hershey, A.D., 1963.
1 27 Hijmans, Jaap, 1965 - 1967.
1 28 Hoffman, John D., 1980 - 1994.
1 29 Janeschitz-Kriegl, H., 1965 - 1997.
1 30 K-Miscellaneous.
1 31 L-Miscellaneous.
1 32 M-Miscellaneous.
1 33 Manning, Gerald S., 1973 - 1985.
1 34 Massie, Harold R., 1981 - 1993.
1 35 Mayer, Joseph E., 1982 - 1994.
1 36 McCammon, Andrew J., 1998.
1 37 Muthukumar, Murugappan, 1988 - 1997.
2 1 N-Miscellaneous.
2 2 Nguyen, Tuan Q., 1987.
2 3 Norden, Bengt, 1987 - 1989.
2 4 P-Miscellaneous.
2 5 Parsegian, Adrian, 1983 - 2002.
2 6 Perkins, Tom, 1994 - 1997.
2 7 Peterlin, Anton, 1957 - 1969.
2 8 Post, Carol, 1987 - 1988.
2 9 Ptitsyn, O.B., 1960 - 1962.
2 10 Q-Miscellaneous.
2 11 Quake, Stephen R., 1996 - 1999.
2 12 R-Miscellaneous.
2 13 Record, M. Thomas, Jr., 1980.
2 14 Rocco, Mattia, 1999. Includes manuscript, 1999.
2 15 Roovers, J., 1983.
2 16 Rose, George E., 1988 - 2001.
2 17 Rubenstein, Irwin, 1969 - 1973.
2 18 S-Miscellaneous.
2 19 Schwartz, David C., 1984 - 2001.
2 20 Serwer, Philip, 1983 - 1990.
2 21 Slater, Gary, 1996.
2 22 Stigter, Dirk, 1982 - 1984.
2 23 Stockmayer, Walter H., 1975 - 1992.
2 24 T-Miscellaneous.
2 25 Thomas, Charles A., 1961 - 1972.
2 26 V-Miscellaneous.
2 27 W-Miscellaneous.
2 28 Weil, G., 1993.
2 29 Worm, Chung, 1998.
2 30 Yamakawa, Hiromi, 1973 - 1983.
2 31 Z-Miscellaneous.
2 32 Zwanzig, Robert, 1964 - 1966.

Chronological

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2 33 August, 1949 - December, 1958.
3 1 January, 1959 - December, 1965.
3 2 April, 1966 - May, 1969.
3 3 March - December, 1970.
3 4 January - December, 1971.
3 5 May - December, 1972.
3 6 January - December, 1973.
3 7 February - December, 1974.
3 8 January - September, 1975.
3 9 January - December, 1977.
3 10 January - December, 1978.
3 11 January - December, 1979.
3 12 January - December, 1980.
3 13 January - December, 1981.
4 1 January - December, 1982.
4 2 January - December, 1983.
4 3 January - November, 1984.
4 4 January, 1985 - November, 1986.
4 5 January, 1987 - December, 1988.
4 6 January, 1989 - December, 1990.
4 7 January - November, 1991.
4 8 January - November, 1992.
4 9 January - December, 1993.
4 10 May, 1994 - September, 1998.

WRITINGS BY ZIMM

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Numbered Reprints

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4 11 Bibliography of Published Work.
4 12 1.- 2. "Some Light Scattering Experiments with High Polymer Solutions", 1944. With P.M. Doty and H. Mark. "The effect of non-homogeneity of molecular weight on the scattering of light by high polymer solutions".
4 13 3. "Vapor Pressures, Heats of Vaporization, and Entropies of Some Alkali Halides", 1944. With Joseph E. Mayer.
4 14 5. "An Investigation of the Determination of Molecular Weights of High Polymers by Light Scattering", 1945. With P.M. Doty and H. Mark.
4 15 7. "Statistical Mechanics of High Polymer Solutions Using Molecular Functions", 1945.
4 16 9. "A Convenient Small Osmometer", 1946. With I. Myerson.
4 17 10. "The Determination of Macromolecular Configurations in Dilute Solution by Light Scattering", 1946. With P.M. Doty and W.A. Affens.
4 18 11. "Light Scattering Studies of Tobacco Mosaic Virus", 1947. With P.M. Doty and H. Mark.
4 19 13. "Apparatus and Methods for Measurement and Interpretation of the Angular Variation of Light Scattering", 1948. Preliminary results on polystyrene solutions.
4 20 14. "The Dependence of the Scattering of Light on Angle and Concentration in Linear Polymer Solutions", 1948.
4 21 16. "Thermodynamic Properties of Concentrated Polystyrene Solutions", 1950. With M.J. Schick and P.M. Doty.
4 22 20. "The Physical Properties of Elinin, a Lipoprotein from Human Erythrocytes", 1950. With W.B. Dandliker, M. Moskowitz, and M. Calvin.
4 23 22. "Contribution to the Theory of Critical Phenomena", 1951.
4 24 23. "Some Special Topics in the Physical Chemistry of High Polymer Solutions", 1951.
4 25 24. "The Molecular Weight of Amylopectin", 1952. With C.D. Thurmond.
4 26 26. "Mechanism of Biradical-Initiated Polymerizations", 1952. With J.K. Bragg.
4 27 27. "The Shape of the Coexistence Curve in the Critical Region", 1952.
4 28 28. "Comments on the Question of the Correct Values for the Light Scattering Powers of Pure Liquids", 1953.
4 29 29. "Simplified Relation Between Thermodynamics and Molecular Distribution Functions for a Mixture", 1953.
4 30 30. "Excluded Volume in Polymer Chains", 1953. With W.H. Stockmayer and M. Fixman.
4 31 31. "Co-Operative Aspects of Phase Transitions", 1953. With R.A. Oriani and J.D. Hoffman.
4 32 32. "Physical Properties of Solutions of Branched Polymers", 1953.
4 33 33. "Theory of Light Scattering and Refractive Index of Solutions of Large Colloidal Particles", 1954. With W.B. Dandliker.
4 34 34. "Rate of Thermal Diffusion of Polymer Molecules in Solution", 1955. With J.D. Hoffman.
4 35 35. "Improved Solution Light Scattering Cell" with F.P. Price, 1955.
4 36 36. "The Gaussian Approximation for a Chain with Fixed Valence Angles", 1955.
5 1 37. "Dynamics of Polymer Molecules in Dilute Solution: Viscoelasticity, Flow Birefringence...", 1956. Includes correspondence and notes.
5 2 38. "Solution of a Characteristic Value Problem from the Theory of Chain Molecules", 1956. With G.M. Roe and L.F. Epstein.
5 3 39. "Relaxation Effects in Polymer Solutions", 1956.
5 4 40. "Sorption of Vapors by High Polymers", 1956. With J.L. Lundberg.
5 5 41. "Monodisperse Polystyrene", 1957. J.P. Bianchi and F.P. Price.
5 6 42. "Vibrating Viscometer for Relaxation Studies on Dilute Polymer Solutions", 1957.
5 7 43. "Photoelectric Flow Birefringence Instrument of High Sensitivity", 1958.
5 8 44. "Theory of One-Dimensional Phase Transition in Polypeptide Chains", 1958. With J.K. Bragg.
5 9 45. "Dilute Gelling Systems. II. Polyesters", 1958. With F.P. Price and J.H. Gibbs.
5 10 46. "Dilute Gelling Systems. IV. Divinylbenzene-Styrene Copolymers", 1958. F.P. Price and J.P. Bianchi.
5 11 47. "Dynamics of Branched Polymer Molecules in Dilute Solution", 1959. With R.W. Kilb.
5 12 48. "Concentrated Macromolecular Solutions", 1959.
5 13 49. "Theory of the Phase Transition Between Helix and Random Coil in Polypetide Chains", 1959. With J.K. Bragg.
5 14 50. "Rotation Friction Coefficient of Models of Tobacco Mosaic Virus and the Size of the Virus Particle", 1959. With A.J. Halther.
5 15 51. "Determination of the Parameters for Helix Formation in Poly-Benzl-L-Glutamate", 1959. With P.M. Doty and K. Iso.
5 16 52. "The Normal-Coordinate Method for Polymer Chains in Dilute Solution", 1959.
5 17 53. "Calculation of the Rate of Uncoiling of the DNA Molecule", 1960. With H.C. Longuet-Higgens.
5 18 54. "The Helix-Coil Transition in Charged Macromolecules", 1960. With S.A. Rice.
5 19 55. "Theory of 'Melting' of the Helical Form in Double Chains of the DNA Type", 1960.
5 20 57. "Mechanisms of Inactivation of Deoxyribonucleic Acids by Heat", 1961. With W. Ginoza.
5 21 60. "The Theory of the Transition Between Helix and Random Coil", 1962.
5 22 61. "Simplified Rotating Cylinder Viscometer for DNA", 1962. With D.M. Crothers. Includes correspondence.
5 23 62. "Selected Aspects of the Physical Chemistry of Polynucleotides and Nucleic Acids", 1962. With N.R. Kallenbach.
5 24 63. "Simplified Theory of the Helix-Coil Transition in DNA Based on a Grand Partition Function", 1963. With S. Lifson. Includes correspondence.
5 25 64. "Theory of Helix-Coil Transitions Involving Complementary Poly- and Oligo-nucleotides", 1963. With W.S. Magee, Jr. and J.H. Gibbs. Includes correspondence.
5 26 65. "Theory of the Melting Transition of Synthetic Polynucleotides: Evaluation of the Stacking Free Energy", 1964. With D.M. Crothers.
5 27 66. "Degradation of Polymers by Controlled Hydrodynamic Shear", 1965. With R.E. Harrington. Includes correspondence.
5 28 67. "The Melting Transition of Low-Molecular-Weight DNA: Theory and Experiment", 1965. With D.M. Crothers and N.R. Kallenbach.
5 29 68. "Viscosity and Sedimentation of the DNA from Bateriophages T2 and T7 and the Relation to Molecular Weight", 1965. With D.M. Crothers. Includes correspondence and notes.
5 30 69. "A New Rotating-Cylinder Viscometer and its Use on DNA Solutions", 1965. Includes correspondence.
5 31 70. "An Acrylamide Gel Soluble in Scintillation Fluid: Its Application to Electrophoresis at Neutral...", 1965. With G.L. Choules.
5 32 71. "Molecular Weight of the DNA in the Chromosomes of E. Coli and B. Subtilis", 1965. With H.R. Massie.
5 33 72. "The Use of Hot Phenol in Preparing DNA", 1965. With H.R. Massie.
5 34 73. "Cluster Theory of Polyelectrolyte Solutions I and II", 1965. With G.S. Manning.
5 35 74. "Viscosity, Sedimentation, et cetera, of Ring-and Straight-Chain Polymers in Dilute Solution", 1966. With V. Bloomfield. Includes graphs.
5 36 75. "Anomalous Plugging of Sintered Glass Filters by High Molecular Weight Polymers", 1968. With R.E. Harrington. Includes correspondence and articles.
5 37 76. "Low-Angle Light Scattering Instrument for DNA Solutions", 1968. With J.A. Harpst and A.I. Krasna. Includes correspondence.
5 38 77. "Molecular Weight of T7 and Calf Thymus DNA by Low-Angle Light Scattering", 1968. With J.A. Harpst and A.I. Krasna.
5 39 78. "Kinetics of Denaturation of DNA", 1969. With H.R. Massie.
5 40 79. "A Computer Simulation of the Unwinding of a DNA-Like Helix", 1969. With E.M. Simon.
5 41 80. "Persistence Length of DNA", 1969. With J.B. Hays and M.E. Magar. Includes correspondence and notes.
5 42 81. "An Instrument for Measuring Retardation Times of Deoxyribonucleic Acid Solutions", 1969. With R.E. Chapman, Jr., L.C. Klotz, and D.S. Thompson.
5 43 82. "Flexibility and Stiffness in Nicked DNA", 1970. With J.B. Hays.
5 44 83."Effect of Concentration and Intermolecular Forces on the Sedimentation of Polystyrene Spheres", 1971. With B. Goldstein.
5 45 85. "A Linearized Chain Model for Dielectric Loss in Polymers", 1972. M. Barkley Clark.
5 46 86. "Kinetics of the Helix-Coil Transition in DNA", 1972. With M. Thomas Record.
5 47 87. "Retardation Times of Deoxyribonucleic Acid Solutions. II. Improvements in Apparatus Theory", 1972. With L.C. Klotz.
5 48 88. "Size of DNA Determined by Viscoelastic Measurements: Results on Bacteriophages, B. Subtilis and E. Coli", 1972.
5 49 89. "Chromosome-Sized DNA Molecules from Drosophila", 1973. With R. Ravenoff.
5 50 90. "Anomalies in Sedimentation. I Stability Theory of Sedimenting Entanglements in the 'Tight-Bending' Limit", 1973. With B. Goldstein.
5 51 91. "Anomalies in Sedimentation. II. Testing the Entanglement Hypothesis", 1973. With V.N. Schumaker.
6 1 92. "Anomalies in Sedimentation III. A Model for the Inherent Instability of Solutions of Very Large Particle", 1973. With V.N. Schumaker.
6 2 95. "On the Nature Chromosome-sized DNA Molecules", 1973. With R. Kavenoff and L.C. Klotz.
6 3 96. "Anomalies in Sedimentation. IV. Decrease in Sedimentation Coefficients on Chains at High Fields", 1974.
6 4 97. "Approximate Theory of the Viscoelasticity of the Chain-Molecule Solutions not Infinitely Dilute", 1974. With F.W. Wang.
6 5 98. "The Viscoelasticity of Polymer Solutions: Comparison of Theory and Experiment", 1974. With F.W. Wong.
6 6 99. "Radical Migration of DNA Molecules in Cylindrical Flow. I. Theory of the Free-Dancing Model", 1974. With R.H. Shafer and N. Laiken.
6 7 100. "Structural Aberrations in T-even Bateriophage. VI. Molecular Weight of DNA from Giant Heads", 1974. With E.L. Uhlenhopp and D.J. Cummings.
6 8 101. "Viscoelastic Characterization of Single-Stranded DNA from Escherichia Coli", 1975. With E.L. Uhlenhopp.
6 9 102. "Simplified Solution of Kirkwood-Riseman Equations for the Intrinsic Viscosity of a Chain Macromolecule", 1975.
6 10 103. "Sizing of Chromosomal DNA Molecules by Hydrodynamic Methods: A Sedimentation Anamoly", 1976.
6 11 104. "Anomalies in Sedimentation. V. Chains a High Fields, Practical Consequences", 1976. With V.N. Schumaker.
6 12 105. "Shear Degradation of DNA", 1977. With R.E. Adam.
6 13 106. "Molecular Weight of T2 NaDNA from Viscoelasticity", 1978. With B.C. Bowen.
6 14 107. "Improvements in Instrumentation of Viscoelasticity of DNA Solution", 1979. With B.C. Bowen.
6 15 108. "Comment on a Paper Boy", 1979. With Fong and Petelin.
6 16 109. "Internal Condensation of a Single DNA Molecule", 1979. With C.B. Post.
6 17 110. "Theory of Twisting and Bending of Chain Macromolecules; Analysis of Flourescence Depolarization of DNA", 1979. With M.D. Barkley.
6 18 111. "A Rhelogical Separator for Very Large DNA Molecules", 1979. With K.A. Dill.
6 19 112. "Dynamics of Polymer Solutions. I. Theory for an Instrument", 1980. With K.A. Dill.
6 20 113. "Dynamics of Polymer Solutions. II.The Determination of Molecular Weight Distribution by Viscoelasticity", 1980.
6 21 114. "Dynamics of Polymer Solutions III. Instrument for Stress Relax. on Dilute Solutions of Lg. Polymer Mol.", 1980. With M. Troll and K.A. Dill.
6 22 115. "Chain Molecule Hydrodynamics by the Monte-Carlo Method and the Validity of the Kirkwood-Riseman Approx.", 1980.
6 23 117. "Novel Cell for Light Scattering from Solutions", 1981. With F.W. Wang.
6 24 118. "Monte Carlo Approach to the Analysis of the Rotational Diffusion of Wormlike Chains", 1981. With P.J. Hagerman.
6 25 119. "Electrostatic and Topological Interactions in DNA", 1981. With M. Le Bret.
6 26 120. "Sedimentation of Asymmetric Elastic Dumbbells and the Rigid-Body Approx. in the Hydrodynamics of Chains", 1982.
6 27 121. "Theory of DNA Condensation: Collapse Versus Aggregation", 1982. With C.B. Post.
6 28 122. "Light-Scattering Study of DNA Condensation: Competition Between Collapse and Aggregation", 1982.
6 29 123. "Mobility of DNA in Gel Electrophoresis", 1982. With O.J. Lumpkin.
6 30 124. "Dielectic Saturation Effects in Cylindrical Polyelectrolytes", 1983. With M. Troll.
6 31 125. "Counter-Ion Condensation and System Dimensionality", 1983. With M. Le Bret.
6 32 126. "Significance of Reversibility of Initiation and of Equilibrium Between Growing and Dormant Polymers...", 1983. With M. Szwarc.
6 33 127. "Ions Around DNA: Monte Carlo Estimates of Distribution with Improved Electrostatic Potentials", 1988. With J. Conrad and M. Troll.
6 34 128. "Distribution of Counterions Around a Cylindrical Polyelectrolyte and Manning's Condensation Theory", 1984. With M. Le Bret.
6 35 129. "Monte Carlo Calculation of the Friction Coefficient and Viscoscity Number of Wormlike Star Molecules", 1984.
6 36 131. "When Polymer Science Looked Easy", 1984. With W.H. Stockmayer.
6 37 132. "An Elastic Hinge Model for Dynamics of Stiff Chains. I. Viscoelastic Properties", 1984. With D.B. Roitman.
6 38 133. "An Elastic Hinge Model for Dynamics of Stiff Chains. II. Transient Electro-Optical Properties", 1984. With D.B. Roitman.
6 39 134. "Theory of Gel Electrophoresis of DNA", 1985. With O.J. Lumpkin.
6 40 135. "Theory of Electrophoresis of Polyelectrolytes Through Gels", 1985. With P. Dejardin and O.J. Lumpkin.
6 41 136. "Measurement of Molecular Weights of Elongated Molecules by Viscoelasticity", 1985. Includes correspondence.
6 42 137. "Use of Poisson-Boltzmann Equation to Predict Ion Condensation Around Polyelectrolytes", 1986.
6 43 138. "Electrostatic Interaction Between Ions and DNA Estimated with an Electrolyte Tank", 1986. With M. Troll, D. Roitman, and J. Conrad.
6 44 139. "Separations of Open-Circular DNA Using Pulsed-Field Electrophoresis", 1987. With S.D. Levene.
6 45 140. "Ions Around DNA: Monte Carlo Estimates of Distribution with Improved Electrostatic Potentials", 1988. With J. Conrad and M. Troll.
6 46 141. "Size Fluctuations Can Explain Anomalous Mobility in Field-Inversion Electrophoresis of DNA", 1988.
6 47 142. "Exactly Solvable Reptation Model", 1989. With O. Lumpkin and S.D. Levene.
6 48 143. "Understanding the Anomalous Electrophoresis of Bent DNA Molecules: A Reptation Model", 1989. With S.D. Levene. Includes correspondence and reprint list.
6 49 144. "Lakes-Straits Model of Field-Inversion Gel Electrophoresis of DNA", 1990.
6 50 145. "Fracture of Polymer Chains in Extensional Flow Experiments with DNA and a Molecular-Dynamics Simulation", 1989.
6 51 146. "The Degradation of T7 DNA in Converging Flow", 1990. With H.R. Reese.
6 52 147. "Lakes-Straits Model of Field-Inversion Gel Electrophoresis of DNA", 1991. Includes graphs.
6 53 149. "Problems and Prospects in the Theory of Gel Electrophoresis of DNA", 1992. With S.D. Levene. Includes correspondence.
6 54 150. "Reptation of a Polymer Chain in an Irregular Matrix: Diffusion and Electrophoresis", 1993. With O. Lumpkin. Includes graphs.
6 55 151. "Measurement of Diffusion Coefficients of DNA in Agarose Gel", 1993. With D.L. Gosnell.
6 56 152. "Mechanism of Gel Electrophoresis of DNA: Unexpected Findings", 1993.
6 57 153. "Joseph Edward Mayer", 1994.

Unnumbered Writings

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6 58 "Aggregation Events Occur Prior to Stable Intermediate Formation During Refolding of Interleukin 1Beta", 2000. With J.M. Finke, M. Roy and P.A. Jennings.
6 59 "Are Denatured Proteins Ever Random Coils?", 2000. With R.L. Baldwin.
6 60 "Commitment to Folded and Aggregated States Occurs Late in Interleukin-1Beta Folding", 2000. With J.M. Finke, L.A. Gross, H.M. Ho, D. Sept and P.A. Jennings.
6 61 "Confirmation-Invariant Structures of the Alpha1Beta1 Human Hemoglobin Dimer", 1997. With W.L. Nichols and L.F. Ten Eyck. Includes correspondence.
6 62 "Dual Influence of Lithium Chloride on the Reactivity of Polystyrylithium in Ethereal Solvents", 1997. With M.V. Beylen, P. Van Lierde and M. Szwarc.
6 63 "Dynamics of Branched Polymer Molecules in Dilute Solutions" - Commentary written with Ralph W. Kilb, 1996.
6 64 "Extension in Flow of a DNA Molecule Tethered at One End", 1998.
6 65 "Gel as an Array of Channels", 1996. Includes graph drawings.
7 1 "German Professor's Trip to Eldorado" - Translation from German, 1990. Original text by Ludwig Boltzmann. "Reise eines deutschen Professors ins Eldorado," 1906.
7 2 "Hydrodynamic Radius: Useful, but Use with Caution". Includes graph drawings and transparencies.
7 3 "Key Papers in the Development of Light-Scattering", 2001. October.
7 4 "Molecular Radius and Molecular-Weight Scaling". Includes graph drawings and transparencies.
7 5 "One Chromosome: One DNA Molecule", TRENDS IN BIOCHEMICAL SCIENCES, 1998. Includes draft copy and correspondence.
7 6 "Radical Migration of DNA Molecules in Cylindrical Flow", with Ken Dill and Richard Shafer - Citation of Zimm, 1976.
7 7 "Rigid Domains in Proteins: An Algorithmic Approach to Their Identification", 1995. With W.L. Nichols, G.D. Rose and L.F. Ten Eyck. Includes correspondence.

Reviewed by

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7 8 Andrews, R.D. TRANSACTIONS OF THE SOCIETY OF RHEOLOGY, Volume 2, 1960.
7 9 Dahneke, Barton. "Measurement of Suspended Particles by Quasi-Elastic Light Scattering", 1983.
7 10 Fernandez, Ariel. "A Parallel Algorithm for Kinetically-Governed Competing Folding Pathways in RNA, 1991.
7 11 Flory, Paul, J.G. Jackson, and C.J. Wood. STATISTICAL MECHANICS OF CHAIN MOLECULES, 1969.
7 12 Heller, W., M. Nakagaki, and G.D. Landoff. "Angular Scattering for Spheroids", 1972.
7 13 Sedlak, Marian. "On the Filterable Aggregates and Other Particles Interpretations...", 1994.
7 14 Vol'Renshtein, Mikhail. "Molecules and Life", 1970 - 1971.

SUBJECT FILES

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Award Recommendation Letters

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7 15 Ferry, John D.
7 16 Kuhn, W., Professor.
7 17 Mayer, Joseph E., 1962 - 1980.
7 18 Stockmayer, Walter, 1962 - 1987.
7 19 Wheeler, John C., 1983 - 1986.
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7 20 Alkali halide calculations.
7 21 Barkley flourescence calculation.
7 22 Born - Green etc.
8 1 Branched molecule calculations.
8 2 Buffers.
8 3 Bumpy road - "Bumpy Road" theory.
8 4 Bumpy road - Tight cell, plots for electrophoresis, SHNTCALS.
8 5 Chain in box.
8 6 Chain in gel.
8 7 Chain stretch.
8 8 Conrad, Joan.
8 9 Critical point.
9 1 Critical point statistical mechanics.
9 2 Data puncher.
9 3 Different equations and polymer statistics.
9 4 Diffusion - Miscellaneous.
9 5 Dumbell diffusion.
9 6 Electronics - Notes on beams "Levitator".
9 7 Electro-optics effect.
9 8 Electrophoresis apparatus.
9 9 Electrophoresis loop-out programs - End-out programs and data, loop-out data.
10 1 Electrophoresis - Rough notes, calculations, etc..
10 2 Electroporation - Wanda Krassowska, Ph. D.
10 3 Ellipsoid calculation.
10 4 Flexible rod calculation - DNA flexibility calculation and computer plots.
10 5 Flow birefringence theory.
10 6 Gel electrophoresis simulation.
10 7 Goodman, Murray, 1980 - 1986.
10 8 H.A. matrix calculation.
10 9 Helinski2- Program to simulate replication of plasmids.
10 10 Hydrodynamics of ellipsoids - Viscosity of ellipsoids - Part 1.
11 1 Hydrodynamics of ellipsoids - Viscosity of ellipsoids - Part 2.
11 2 Kerr Effect.
11 3 K-R Monte Carlo.
11 4 Light scattering - Notes and handwritten manuscript notes for book proposal.
11 5 Light scattering - Photometer, 1950 - 2000.
11 6 Light scattering theory: large molecules.
11 7 Light scattering theory: small molecules.
11 8 Miscellaneous handwritten equations and notes.
11 9 Miscellaneous lecture transparencies from reprints.
11 10 Molecular distribution functions and polymers - A2.
12 1 "Novel Cell for Light Scattering from Solutions" - Lecture transparencies, 1981.
12 2 One-dimensional magnets.
12 3 Pattern formation.
12 4 Polyelectrolyte helix - Coil theory.
12 5 Polyelectrolytes: Le Bret program, troll programs - 4 typset.
12 6 Polyelectrolytes Poisson-Boltzmann equation.
12 7 Polynucleotide theory.
12 8 Prolate ellipsoids.
12 9 Protein folding.
12 10 Protein "Simplification" project.
12 11 Protein "Simplification" project - Programs.
12 12 Reiss - "Sedimentation Work".
12 13 Reptation programs.
12 14 Rice theorem.
12 15 Sailing dynamics.
12 16 Sediman anomaly.
13 1 Sediman anomaly - Velocity dependence of "S".
13 2 Shear rate and viscosity first calculation - Shear rate material and Bueche correspondence.
13 3 Shear rate and viscosity first calculation - Springs in flow, simulation.
13 4 Soviet polymer science.
13 5 Statistical problems, miscellaneous - Classical and quantum statistical mechanics.
13 6 Supercoil programs.
13 7 Supercoils - Associated programs.
13 8 Supercoils: Le Bret papers and correspondence.
13 9 Supercoils - Fuller's internal for writhe.
13 10 Supercoils - Supercage programs.
13 11 Szwarc calculations, 1982.
13 12 Turbo Pascal program - Problems - Part 1, 1984 - 1990.
14 1 Turbo Pascal program - Problems - Part 2, 1984 - 1990.
14 2 Viral coefficients.
14 3 Viral theorem - Miscellaneous.
14 4 Warren - DNA.
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14 5 Retardimeter - Figure graph drawings.
14 6 Retardimeter apparatus - Drawings - Lynn Klotz notes, 1969.
14 7 Various apparatus drawings, 1947 - 1971.
14 8 Viscoelastometer frame - Drawings, 1916.
14 9 Miscellaneous scientific drawings - Part 1. Includes pen and ink drawings of graphs, charts and apparatuses.
14 10 Miscellaneous scientific drawings - Part 2. Includes pen and ink drawings of graphs, charts, and apparatuses.
14 11 Miscellaneous scientific drawings - Part 3. Includes transparencies and gloss prints.
14 12 Miscellaneous scientific drawings - Part 4. Includes 35mm slides of apparatus data and charts.

GRANT MATERIALS

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14 13 "Device for and a Method to Separate Orientable or Deformable Particles" - Co-Investigated with K. Dill, 1979 - 1983. Includes correspondence and patent applications.
14 14 "Device for Improved Gel Electrophoresis of DNA" - Co-Investigated with Wesley B. Ames, 1985 - 1987. Includes correspondence and patent description.
14 15 Szwarc, Michael - Research funded projects for Bruno Zimm, 1994.
14 16 Wyatt Technologies - Correspondence, 1986 - 1989.
15 1 Wyatt Technologies - Correspondence, 1990 - 1993. Includes research project grant "Dynamic of Macromolecules" with budget allocation.
15 2 Wyatt Technologies - Correspondence, 1994 - 2001.

GENERAL ELECTRIC COMPANY

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15 3 "Kerr (Electro-Optical) Effect as a Means of Studying Colloidal Solutions", 1952. July. Memo report C-114 chemistry research department - Research laboratory.
15 4 "Permeability of Plastics to Gases," with F.J. Norton, 1953. February. Memo report C-281 physical chemistry section.
15 5 POST (Corporate) Research and Development - Newsletters, 1968 - 1979.
15 6 "Study Program in Biophysical Science at Boulder, Colorado", 1958. July to August. Memo report C-58-195 chemistry research department - Research laboratory.
15 7 "Vibration Viscosity of Polymer Solutions," Research Laboratory MEMO, Volume II, Number 6, 1957. June.
15 8 "Viscoelastic Properties of Dilute Chain-Molecule Solutions", 1953.

TEACHING MATERIALS

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15 9 Department of Chemistry - Faculty and graduate student - Photographs, 1968 - 2001.
15 10 Biology-Chemistry 113-213 - Answers to scattering problems.
15 11 Biology-Chemistry 113-213 - Dynamic light scattering and diffusion coefficients, 1980. Fall.
15 12 Biology-Chemistry 113-213 - Electrophoresis handout (Baja).
15 13 Biology-Chemistry 113-213 - Electrophoresis problems, 1979. Fall.
15 14 Biology-Chemistry 113-213 - Handout of Perrin's factor chart.
15 15 Biology-Chemistry 113-213 - Final exam key, 1985 - 1987.
15 16 Biology-Chemistry 113-213 - Flourescence energy transfer, 1979. Fall.
15 17 Biology-Chemistry 113-213 - Gel filtration (Sephandex handout).
15 18 Biology-Chemistry 113-213 - Gel permeation problem.
16 1 Biology-Chemistry 113-213 - Homework originals, 1974 - 1979.
16 2 Biology-Chemistry 113-213 - Homework problems 1-3, 1985. Fall.
16 3 Biology-Chemistry 113-213 - Homework problem 3A, 1977.
16 4 Biology-Chemistry 113-213 - Homework problems 4 and 5, 1976. Spring.
16 5 Biology-Chemistry 113-213 - Hydrodynamic radius as a correlating concept handout, 1978. November.
16 6 Biology-Chemistry 113-213 - Immunodiffusion and immunoelectrophoresis problems, 1981. Fall.
16 7 Biology-Chemistry 113-213 - Lecture notes, 1965 - 1985.
16 8 Biology-Chemistry 113-213 - Notes on hydrophobicity, 1976.
16 9 Biology-Chemistry 113-213 - Notes on scattering vector, 1975. May.
16 10 Biology-Chemistry 113-213 - Polyelectrolyte notes, 1980. Fall.
16 11 Biology-Chemistry 113-213 - Special problems.
16 12 Biology-Chemistry 113-213 - Spectroscopy and flourescence problems, 1979. Fall.
16 13 Biology-Chemistry 113-213 - Study topics, 1991.
16 14 Chemistry 107 - Book requisition forms and reserves lists, 1984 - 1990.
16 15 Chemistry 107 - CAPE evaluations, 1989. Winter.
16 16 Chemistry 107 - Lecture notes.
16 17 Chemistry 107 - Midterms and study guides, 1970 - 1975.
16 18 Macromolecule 107-207 - Notes, 1975.
16 19 Macromolecule courses - Miscellaneous background and notes, 1966 - 1977.
16 20 Natural Science 1BL/ Natural Science 2DS - Laboratory experiments - Handbook revised by Bruno Zimm, 1974. November.
17 1 Natural Science 2DL, Science 3AL - Introduction and first experiment, 1977.
17 2 "Polymer Dynamics and Thermodynamics in Solutions" Walter H. Stockmayer Symposium, San Diego, CA, 1994. March. Includes "Diffusion and Electrophoresis of a Polyelectrolyte in an Irregular Matrix" - Presentation and transparencies.

LABORATORY NOTEBOOKS

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17 3 General Electric - Laboratory notes, N.B. 5026, 1950 - 1953.
17 4 General Electric - Laboratory notes, N.B. 5676, 1953 - 1954.
17 5 General Electric - Laboratory notes, N.B. 6127, 1954 - 1956.
17 6 General Electric - Laboratory notes, N.B. 6637, 1956 - 1960.
17 7 General Electric - Laboratory notes, Barnes N.B. 6835, 1957.
17 8 General Electric - Laboratory notes, Barnes N.B. 6913, 1958.
17 9 Osmometer zero points calibration.
17 10 Record book, 1961. September.
18 1 Theoretical research diary, 1960. November.
18 2 Theoretical research diary, 1961 - 1975. July to August.
18 3 Theoretical research diary, 1975 - 1979. August to January.
18 4 Theoretical research diary, 1979 - 1983. January to November.
18 5 Theoretical research diary, 1983 - 1987. November to June.
18 6 Theoretical research diary, 1987 - 1991. June to December.
18 7 Theoretical research diary, 1991. December.
18 8 Transformation project, 1962. March.

BIOGRAPHICAL MATERIALS

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19 1 American Physical Society Chemical Physics prize "Irving Langmuir" committee, 1963 - 1965.
19 2 Articles about Bruno Zimm.
19 3 Awards.
19 4 Beckman Center for the History of Chemistry - Transcript of an interview of Bruno Zimm, 1986. September. Conducted by James J. Bohning.
19 5 Biographies, 1985 - 1989.
19 6 Columbia University - "A Synthesis of Tyrian Purple" - Organic chemistry special project, 1941. April.
19 7 Columbia University - Chemistry and quantum mechanics physics course material, 1942. Includes notes, exams, and "Calibration of Weights" typescript.
19 8 Columbia University - Phi Beta Kappa - Inductee correspondence, 1942.
19 9 Columbia University - Miscellaneous report documents, 1941 - 1942.
19 10 Curriculum vitae.
19 11 Identification cards.
19 12 Personal statement, 1969. August.
19 13 Photographs of Bruno Zimm.
19 14 Photographs of others.
19 15 Professional dossier.
19 16 Promotions, 1942 - 1995.
19 17 War Manpower Commission - Committee on Scientific Research Personnel - Letters, 1944. Includes authorized diploma.



Finding aid generated: 2007-09-10