Recent UCSD Bioengineering Articles

Recent articles from the UCSD Department of Bioengineering Faculty:

Bjursten, L. M., Rasmusson, L., Oh, S., Smith, G. C., Brammer, K. S. and Jin, S. (2010) ‘Titanium dioxide nanotubes enhance bone bonding in vivo‘, Journal of Biomedical Materials Research Part A, 92A(3), 1218-1224.

Danino, T., Mondragon-Palomino, O., Tsimring, L. and Hasty, J. (2010) ‘A synchronized quorum of genetic clocks‘, Nature, 463(7279), 326-330.

Feng, Z. L., Zhao, G., Yu, L., Gough, D. and Howell, S. B. (2010) ‘Preclinical efficacy studies of a novel nanoparticle-based formulation of paclitaxel that out-performs Abraxane‘, Cancer Chemotherapy and Pharmacology, 65(5), 923-930.

Konig, R., Stertz, S., Zhou, Y., Inoue, A., Hoffmann, H. H., Bhattacharyya, S., Alamares, J. G., Tscherne, D. M., Ortigoza, M. B., Liang, Y. H., Gao, Q. S., Andrews, S. E., Bandyopadhyay, S., De Jesus, P., Tu, B. P., Pache, L., Shih, C., Orth, A., Bonamy, G., Miraglia, L., Ideker, T., Garcia-Sastre, A., Young, J. A. T., Palese, P., Shaw, M. L. and Chanda, S. K. (2010) ‘Human host factors required for influenza virus replication‘, Nature, 463(7282), 813-817.

Liu, T. T. and Liau, J. (2010) ‘Caffeine increases the linearity of the visual BOLD response‘, Neuroimage, 49(3), 2311-2317.

Loizos, D. N., Sotiriadis, P. P. and Cauwenberghs, G. (2010) ‘A SiGe BiCMOS Eight-Channel Multidithering Sub-Microsecond Adaptive Controller‘, IEEE Transactions on Circuits and Systems I-Regular Papers, 57(1), 53-63.

Sah, R. L. and Ratcliffe, A. (2010) ‘Translational Models for Musculoskeletal Tissue Engineering and Regenerative Medicine‘, Tissue Engineering Part B-Reviews, 16(1), 1-3.

Tsai, A. G., Cabrales, P. and Intaglietta, M. (2010) ‘The Physics of Oxygen Delivery: Facts and Controversies‘, Antioxidants & Redox Signaling, 12(6), 683-691.

van Steensel, B., Braunschweig, U., Filion, G. J., Chen, M., van Bemmel, J. G. and Ideker, T. (2010) ‘Bayesian network analysis of targeting interactions in chromatin‘, Genome Research, 20(2), 190-200.

Wang, K. C., Garmire, L. X., Young, A., Nguyen, P., Trinh, A., Subramaniam, S., Wang, N. P., Shyy, J. Y. J., Li, Y. S. and Chien, S. (2010) ‘Role of microRNA-23b in flow-regulation of Rb phosphorylation and endothelial cell growth‘, Proceedings of the National Academy of Sciences of the United States of America, 107(7), 3234-3239.

Zhang, L., Pornpattananangkul, D., Hu, C. M. J. and Huang, C. M. (2010) ‘Development of Nanoparticles for Antimicrobial Drug Delivery‘, Current Medicinal Chemistry, 17(6), 585-594.

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Chemistry Faculty Talk on Science and Policy, Mar 30

Dr. Seth Cohen will talk about his “View from the Top: The Intersection of Science and Policy in the Capital” on March 30, 2010 from 12-1 PM in the UCSD Biomedical Library Events Room.  This lunchtime seminar is jointly sponsored by the Biomedical Library and the Science and Engineering Library.

Dr. Cohen is an Associate Professor in the UCSD Department of Chemistry and Biochemistry.  He obtained a B.S. degree in Chemistry and a B.A. degree in Political Science from Stanford University.  He received his Ph.D. from UC Berkeley and did his postdoctoral research at the Massachusetts Institute of Technology.  He then moved to his present position at UCSD.  His research and teaching at UCSD has been recognized with an NSF CAREER award and a Cottrell Scholar Award from the Research Corporation.

During 2008-2009, he was on sabbatical leave in Washington D.C. as the recipient of the American Association for the Advancement of Science (AAAS) Roger Revelle Fellowship in Global Stewardship.   The Roger Revelle Fellowship is designed to engage practicing scientists in the science policy arena.  Named after one of UCSD’s founders, and Revelle College’s namesake, this fellowship focuses on issues of “global stewardship” such as climate change, environmental stewardship, sustainable energy, and renewable resources.

Dr. Cohen’s fellowship allowed him to obtain a position within the Office of Science and Technology Policy (OSTP).  The OSTP director is the Presidential Science Advisor.  Dr.  Cohen served under two Presidential administrations and two OSTP directors:  Dr. John H. Marburger (Bush administration) during the first six months, and Dr. John Holdren (Obama administration) during the last six months.  While he was at OSTP, he worked on a number of subjects including Presidential transition for OSTP, energy, biomedical research, scientific awards, and scientific integrity.  Come hear Dr. Cohen share his insights and observations about his experiences in Washington, D.C.

Space is limited so RSVP as soon as possible in order to reserve a seat.  Feel free to bring a discreet lunch; cookies and water will be provided.

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Recent UCSD Chemistry, Biochemistry Articles

Recent articles from the Department of Chemistry & Biochemistry faculty:

Agrawal, A.; Johnson, S. L.; Jacobsen, J. A.; Miller, M. T.; Chen, L. H.; Pellecchia, M.; Cohen, S. M., Chelator Fragment Libraries for Targeting Metalloproteinases. ChemMedChem 2010, 5 (2), 195-199.

Durrant, J. D.; Amaro, R. E.; Xie, L.; Urbaniak, M. D.; Ferguson, M. A. J.; Haapalainen, A.; Chen, Z. J.; Di Guilmi, A. M.; Wunder, F.; Bourne, P. E.; McCammon, J. A., A Multidimensional Strategy to Detect Polypharmacological Targets in the Absence of Structural and Sequence Homology. Plos Computational Biology 2010, 6 (1).

Esposito, M.; Lindenberg, K.; Van den Broeck, C., Extracting chemical energy by growing disorder: efficiency at maximum power. Journal of Statistical Mechanics-Theory and Experiment 2010.

Glover, S. D.; Goeltz, J. C.; Lear, B. J.; Kubiak, C. P., Inter- or intramolecular electron transfer between triruthenium clusters: we’ll cross that bridge when we come to it. Coordination Chemistry Reviews 2010, 254 (3-4), 331-345.

Hayden, A. E.; Paton, R. S.; Becker, J.; Lim, Y. H.; Nicolaou, K. C.; Houk, K. N., Origins of Regioselectivity of Diels-Alder Reactions for the Synthesis of Bisanthraquinone Antibiotic BE-43472B. Journal of Organic Chemistry 2010, 75 (3), 922-928.

Paesani, F.; Voth, G. A., A quantitative assessment of the accuracy of centroid molecular dynamics for the calculation of the infrared spectrum of liquid water. Journal of Chemical Physics 2010, 132 (1).

Park, J. H.; von Maltzahn, G.; Xu, M. J.; Fogal, V.; Kotamraju, V. R.; Ruoslahti, E.; Bhatia, S. N.; Sailor, M. J., Cooperative nanomaterial system to sensitize, target, and treat tumors. Proceedings of the National Academy of Sciences of the United States of America 2010, 107 (3), 981-986.

Salgado, E. N.; Ambroggio, X. I.; Brodin, J. D.; Lewis, R. A.; Kuhlman, B.; Tezcan, F. A., Metal templated design of protein interfaces. Proceedings of the National Academy of Sciences of the United States of America 2010, 107 (5), 1827-1832.

Savee, J. D.; Mann, J. E.; Continetti, R. E., Dissociative Charge Exchange Dynamics of HOCO+ and DOCO+. Journal of Physical Chemistry A 2010, 114 (3), 1485-1491.

Watrous, J.; Burns, K.; Liu, W. T.; Patel, A.; Hook, V.; Bafna, V.; Barry, C. E.; Bark, S.; Dorrestein, P. C., Expansion of the mycobacterial “PUPylome”. Molecular Biosystems 2010, 6 (2), 376-385.

Yasgar, A.; Foley, T. L.; Jadhav, A.; Inglese, J.; Burkart, M. D.; Simeonov, A., A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase. Molecular Biosystems 2010, 6 (2), 365-375.

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Dynes, Taylor Elected to NAS Governing Council

This week Robert C. Dynes (Department of Physics and former UCSD Chancellor/UC President) and Susan S. Taylor (Dept of Chemistry & Biochemistry) were elected to the governing council of the National Academy of Sciences. They will begin their 3-year term as Councilors in July.

Larry Squire, a professor of psychiatry at UC San Diego, currently serves on the academy’s governing council, which means three of the 12 members of the governing council are now from UC San Diego, a remarkable achievement for any research institution. –from the UCSD Press Release

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Profs. Coil, Tezcan Named 2010 Sloan Research Fellows

Congratulations to Alison L. Coil (Dept. of Physics, Center for Astrophysics & Space Sciences) and F. Akif Tezcan (Dept. of Chemistry & Biochemistry), who were among the 118 (17 from the UC’s) early career scientists, mathematicians and economists named as Alfred P. Sloan Research Fellows for 2010. Each will received a $50,000 grant for a two-year period.

“The Sloan Research Fellowships support the work of exceptional young researchers early in their academic careers, and often at pivotal stages in their work,” says Paul L. Joskow, President of the Alfred P. Sloan Foundation. “I am proud of the Foundation’s rich history in providing the resources and flexibility necessary for young researchers to enhance their scholarship, and I look forward to the future achievements of the 2010 Sloan Research Fellows.” (from the press release)

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Recent UCSD Articles: Nanoengineering and Materials Science

Recent articles from faculty in the UCSD Department of Nanoengineering and Material Science and Engineering Program:

Arya, G., Energetic and Entropic Forces Governing the Attraction between Polyelectrolyte-Grafted Colloids. Journal of Physical Chemistry B 2009, 113 (48), 15760-15770.

Bandaru, P. R.; Pichanusakorn, P., An outline of the synthesis and properties of silicon nanowires. Semiconductor Science and Technology 2010, 25 (2).

Hwang, Y. S.; Zhang, C.; Varghese, S., Poly(ethylene glycol) cryogels as potential cell scaffolds: effect of polymerization conditions on cryogel microstructure and properties. Journal of Materials Chemistry 2010, 20 (2), 345-351.

Jiang, F. C.; Kulin, R. M.; Vecchio, K. S., Use of Brazilian Disk Test to Determine Properties of Metallic-Intermetallic Laminate Composites. JOM 2010, 62 (1), 35-40.

Kulin, R. M.; Chen, P. Y.; Jiang, F. C.; McKittrick, J.; Vecchio, K. S., Dynamic Fracture Resilience of Elk Antler: Biomimetic Inspiration for Improved Crashworthiness. JOM 2010, 62 (1), 41-46.

Lu, W. Y.; Punyamurtula, V. K.; Han, A. J.; Kim, T.; Qiao, Y., A thermally sensitive energy-absorbing composite functionalized by nanoporous carbon. Journal of Materials Research 2009, 24 (11), 3308-3312.

Simberg, D.; Zhang, W. M.; Merkulov, S.; McCrae, K.; Park, J. H.; Sailor, M. J.; Ruoslahti, E., Contact activation of kallikrein-kinin system by superparamagnetic iron oxide nanoparticles in vitro and in vivo. Journal of Controlled Release 2009, 140 (3), 301-305.

Zhang, L.; Pornpattananangkul, D.; Hu, C. M. J.; Huang, C. M., Development of Nanoparticles for Antimicrobial Drug Delivery. Current Medicinal Chemistry 2010, 17 (6), 585-594.

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UCSD Astronomer Geoffrey Burbidge dies at age 84

Geoff Burbidge and his wife Margaret Burbidge were founding professors of UCSD’s Physics Department. He was a prominent astrophysicist & member of the Center for Astronomy and Space Sciences.

Discover Magazine’s 2005 article “Two Against the Big Bang” on the Burbidges explains the significance of their research. Geoffrey and Margaret Burbidge

See also the UCSD press release or the San Diego Union Tribune obituary for an overview of his life and accomplishments.

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Nano Cocktails That Target, Kill Tumors

Cooperative nanomaterial system to sensitize, target, and treat tumors
Ji-Ho Park, Geoffrey von Maltzahnc, Mary Jue Xuc, Valentina Fogald, Venkata Ramana Kotamrajue, Erkki Ruoslahtid, Sangeeta N. Bhatiac, Michael J. Sailor
Published in PNAS 12/28/2009

Press release from UCSD about this article: Researchers Develop “Nano Cocktail” to Target and Kill Tumors. See also: Computerworld, Medical News Today, Science Daily.

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New UCSD Articles: Mathematics

Recent articles from the UCSD Department of Mathematics faculty:

Bick, C., and M. I. Rabinovich. 2009. Dynamical origin of the effective storage capacity in the brain’s working memory. Physical Review Letters 103 (21): 218101.

Chan, P. S., and Y. Z. Flicker. 2009. Cyclic odd degree base change lifting for unitary groups in three variables. International Journal of Number Theory 5 (7):1247-1309.

Fialkow, L., and J. W. Nie. 2010. Positivity of Riesz functionals and solutions of quadratic and quartic moment problems. Journal of Functional Analysis 258 (1):328-356.

Hazrat, R., and A. R. Wadsworth. 2009. On maximal subgroups of the multiplicative group of a division algebra. Journal of Algebra 322 (7):2528-2543.

Huang, X. J., and Y. Zhang. 2009. Monotonicity for the Chern-Moser-Weyl curvature tensor and CR embeddings. Science in China Series A-Mathematics 52 (12):2617-2627.

Huang, Y., D. Meyer, and S. Nemat-Nasser. 2009. Damage detection with spatially distributed 2D Continuous Wavelet Transform. Mechanics of Materials 41 (10):1096-1107.

Ji, S. Y., and Y. Zhang. 2009. Classification of rational holomorphic maps from B-2 into B-N with degreee 2. Science in China Series A-Mathematics 52 (12):2647-2667.

Kemkes, G., X. Perez-Gimenez, and N. Wormald. 2010. On the chromatic number of random d-regular graphs. Advances in Mathematics 223 (1):300-328.

Kitaev, S., J. Liese, J. Remmel, and B. E. Sagan. 2009. Rationality, irrationality, and Wilf equivalence in generalized factor order. Electronic Journal of Combinatorics 16 (2).

Marek, V. W., and J. B. Remmel. 2009. The complexity of recursive constraint satisfaction problems. Annals of Pure and Applied Logic 161 (3):447-457.

Politis, D. N., and J. P. Romano. 2010. K-sample subsampling in general spaces: The case of independent time series. Journal of Multivariate Analysis 101 (2):316-326.

Popescu, C. D. 2009. On the Coates-Sinnott Conjecture. Mathematische Nachrichten 282 (10):1370-1390.

Rogalski, D. 2009. GK-dimension of birationally commutative surfaces. Transactions of the American Mathematical Society 361 (11):5921-5945.

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Kahng and Rao Named 2010 IEEE Fellows

Congratulations to Professors Kahng and Rao, among the 309 senior IEEE members who have been elevated to IEEE Fellows.

Andrew B. Kahng, for contributions to the design for manufacturability of integrated circuits, and the technology roadmap of semiconductors. Professor Kahng heads up the UCSD VLSI CAD Laboratory.

Ramesh Rao, for leadership in wireless communications. Professor Rao is the UCSD Director of the California insitute for Telecommunications and Information Technology (Calit2).

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